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Published in: Head & Face Medicine 1/2006

Open Access 01-12-2006 | Research

Clinicopathological analysis of histological variants of ameloblastoma in a suburban Nigerian population

Authors: Kehinde E Adebiyi, Vincent I Ugboko, Ganiat O Omoniyi-Esan, Kizito C Ndukwe, Fadekemi O Oginni

Published in: Head & Face Medicine | Issue 1/2006

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Abstract

Background

This study was carried out to establish the relative incidence and provide clinico-pathologic information on the various histological types of ameloblastoma seen at the Obafemi Awolowo University Teaching Hospital complex, Ile-Ife in order to provide a baseline data which will be of significance to the pathologist and clinician.

Methods

Clinico-pathologic data on a total of 77 histologically diagnosed cases of ameloblastoma archieved at the Obafemi Awolowo University Teaching Hospital Complex, Ile-Ife over a 15 year period were obtained and analysed descriptively.

Results

Follicular ameloblastoma was the most common histological type (50 cases, 64.9%), followed by plexiform ameloblastoma (10 cases, 13.0%). 4 (5.2%) cases of desmoplastic and 3 (3.9%) cases of acanthomatous ameloblastoma were seen while the basal cell variant accounted for 2 (2.6%) cases. Only 1 case of the unicystic type was seen. Some of the 77 cases presented as a mixture of two or more histological types. Ameloblastoma occurred over an age range of 11 to 70 years with a peak age incidence in the 3rd decade.

Conclusion

This study provides a baseline data on variants of ameloblastoma as obtained in a suburban Nigerian population. Since variants of ameloblastoma differ in biologic behaviour, the data collected in this study provides clinicopathologic information which is of significance to the pathologist and clinician.
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Literature
1.
go back to reference Woo S, Smith-Williams JE, Sciubba JJ, Lippers S: Peripheral Ameloblastoma of the Buccal Mucosa: Case Report and Review of the English literature. Oral surg, Oral Med Oral pathol. 1987, 67: 78-84. 10.1016/0030-4220(87)90344-6.CrossRef Woo S, Smith-Williams JE, Sciubba JJ, Lippers S: Peripheral Ameloblastoma of the Buccal Mucosa: Case Report and Review of the English literature. Oral surg, Oral Med Oral pathol. 1987, 67: 78-84. 10.1016/0030-4220(87)90344-6.CrossRef
2.
go back to reference Shafer WG, Hine MK, Levy BM, Tomich CE: Ectodermal Tumours of odontogenic origin. 1983, Philadelphia J.B. Saunders, 276-292. Shafer WG, Hine MK, Levy BM, Tomich CE: Ectodermal Tumours of odontogenic origin. 1983, Philadelphia J.B. Saunders, 276-292.
3.
go back to reference Spouge JD: Odontogenic Tumours. A. Unitarian Concepts. Oral Surg Oral Med Oral Pathol. 1967, 24: 392-403. 10.1016/0030-4220(67)90080-1.CrossRefPubMed Spouge JD: Odontogenic Tumours. A. Unitarian Concepts. Oral Surg Oral Med Oral Pathol. 1967, 24: 392-403. 10.1016/0030-4220(67)90080-1.CrossRefPubMed
4.
go back to reference Kramer IRH, Pindborg JJ, Shear M: The World Health Organisation Histological Typing of Odontogenic Tumours. Oral Oncol, Eur J Cancer. 1992, 29B: 169-171. Kramer IRH, Pindborg JJ, Shear M: The World Health Organisation Histological Typing of Odontogenic Tumours. Oral Oncol, Eur J Cancer. 1992, 29B: 169-171.
5.
go back to reference Smith C J: Odontogenic Neoplasms and Harmatomas. Oral Disease in the tropics. 1992, New York: Oxford University Press, 367-385. Smith C J: Odontogenic Neoplasms and Harmatomas. Oral Disease in the tropics. 1992, New York: Oxford University Press, 367-385.
6.
go back to reference Mosadomi A: Odontogenic Tumours in an African Population. Analysis of twenty- nine cases seen over a 5 years period. Oral Surg. 1975, 40: 502-521. 10.1016/0030-4220(75)90248-0.CrossRefPubMed Mosadomi A: Odontogenic Tumours in an African Population. Analysis of twenty- nine cases seen over a 5 years period. Oral Surg. 1975, 40: 502-521. 10.1016/0030-4220(75)90248-0.CrossRefPubMed
7.
go back to reference Odukoya O: Odontogenic Tumours: Analysis of 289 Nigerian cases. J Oral Pathol Med. 1995, 24: 454-457. 10.1111/j.1600-0714.1995.tb01133.x.CrossRefPubMed Odukoya O: Odontogenic Tumours: Analysis of 289 Nigerian cases. J Oral Pathol Med. 1995, 24: 454-457. 10.1111/j.1600-0714.1995.tb01133.x.CrossRefPubMed
8.
go back to reference Adebiyi KE, Odukoya o, Taiwo EO: Ectodermal Odontogenic Tumours: analysis of 197 Nigerian cases. Int J Oral Maxillofac Surg. 2004, 33: 766-770.CrossRefPubMed Adebiyi KE, Odukoya o, Taiwo EO: Ectodermal Odontogenic Tumours: analysis of 197 Nigerian cases. Int J Oral Maxillofac Surg. 2004, 33: 766-770.CrossRefPubMed
9.
go back to reference Ochsenius G, Ortega A, Godoy L, Penafiel C, Escobar E: Odontogenic Tumors in Chile: a study of 362 cases. J Oral Pathol Med. 2002, 31: 415-420. 10.1034/j.1600-0714.2002.00073.x.CrossRefPubMed Ochsenius G, Ortega A, Godoy L, Penafiel C, Escobar E: Odontogenic Tumors in Chile: a study of 362 cases. J Oral Pathol Med. 2002, 31: 415-420. 10.1034/j.1600-0714.2002.00073.x.CrossRefPubMed
10.
go back to reference Santos JN, Pinto LP, de Figueredo CR, de Souza LB: Odontogenic Tumors: Analysis of 127 cases. Pesqui Odontol Bras. 2001, 15 (4): 308-313. 10.1590/S1517-74912001000400007.CrossRefPubMed Santos JN, Pinto LP, de Figueredo CR, de Souza LB: Odontogenic Tumors: Analysis of 127 cases. Pesqui Odontol Bras. 2001, 15 (4): 308-313. 10.1590/S1517-74912001000400007.CrossRefPubMed
11.
go back to reference Regezi JA, Sciubba J: Odontogenic Tumors. Oral pathology. Clinical- pathologic correlations. 1999, Philadelphia: Saunders, 323-356. Regezi JA, Sciubba J: Odontogenic Tumors. Oral pathology. Clinical- pathologic correlations. 1999, Philadelphia: Saunders, 323-356.
12.
go back to reference Chapple ILC, Manogue M: Management of a recurrent follicular ameloblastoma. Dent Update. 1991, 1: 309-312. Chapple ILC, Manogue M: Management of a recurrent follicular ameloblastoma. Dent Update. 1991, 1: 309-312.
13.
go back to reference Akinosi JO, Williams AD: Adamantinoma in Ibadan Nigeria. The W.A.M.J. 1968, 45-49. Akinosi JO, Williams AD: Adamantinoma in Ibadan Nigeria. The W.A.M.J. 1968, 45-49.
14.
go back to reference Subbuswamy SG, Shamia RI: Oral and maxillofacial Tumour in Northern Nigerian: An analysis over five years. Int J Oral Surg. 1981, 10: 255-260.CrossRefPubMed Subbuswamy SG, Shamia RI: Oral and maxillofacial Tumour in Northern Nigerian: An analysis over five years. Int J Oral Surg. 1981, 10: 255-260.CrossRefPubMed
15.
go back to reference Kim SG, Jang HS: Ameloblastoma: A clinical, radiographic, and histopathologic analysis of 71 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2001, 91 (6): 649-653.CrossRefPubMed Kim SG, Jang HS: Ameloblastoma: A clinical, radiographic, and histopathologic analysis of 71 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2001, 91 (6): 649-653.CrossRefPubMed
16.
go back to reference Ladeinde AL, Ajayi OF, Ogunlewe MO, Adeyemo WL, Arotiba GT, Bamgbose BO, Akinwande JA: Odontogenic tumors: A review of 319 cases in a Nigerian teaching hospital. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2005, 99: 191-195. 10.1016/j.tripleo.2004.08.031.CrossRefPubMed Ladeinde AL, Ajayi OF, Ogunlewe MO, Adeyemo WL, Arotiba GT, Bamgbose BO, Akinwande JA: Odontogenic tumors: A review of 319 cases in a Nigerian teaching hospital. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2005, 99: 191-195. 10.1016/j.tripleo.2004.08.031.CrossRefPubMed
17.
go back to reference Waldron CA, El-Mofty SK: A Histopathologic study of 116 Amelobastoma with special reference to the Desmoplastic variant. Oral Surg Oral Med Oral pathol. 1987, 63: 441-451. 10.1016/0030-4220(87)90257-X.CrossRefPubMed Waldron CA, El-Mofty SK: A Histopathologic study of 116 Amelobastoma with special reference to the Desmoplastic variant. Oral Surg Oral Med Oral pathol. 1987, 63: 441-451. 10.1016/0030-4220(87)90257-X.CrossRefPubMed
18.
go back to reference Günhan O, Erseven G, Ruacan S, Celasun B, Aydintug Y, Ergun E, Demiriz M: Odontogenic tumors: a series of 409 cases. Austr Dent J. 1990, 35: 518-522.CrossRef Günhan O, Erseven G, Ruacan S, Celasun B, Aydintug Y, Ergun E, Demiriz M: Odontogenic tumors: a series of 409 cases. Austr Dent J. 1990, 35: 518-522.CrossRef
19.
go back to reference Regezi JA, Kerr DA, Courtney RM: Odontogenic tumors: analysis of 706 cases. J Oral Surg. 1978, 36: 771-778.PubMed Regezi JA, Kerr DA, Courtney RM: Odontogenic tumors: analysis of 706 cases. J Oral Surg. 1978, 36: 771-778.PubMed
20.
go back to reference Ladeinde AL, Ogunlewe MO, Bamgbose BO, Adeyemo WL, Ajayi OF, Arotiba GT, Akinwande JA: Ameloblastoma: analysis of 207 cases in a Nigerian teaching hospital. Quintessence Int. 2001, 37 (1): 69-74. Ladeinde AL, Ogunlewe MO, Bamgbose BO, Adeyemo WL, Ajayi OF, Arotiba GT, Akinwande JA: Ameloblastoma: analysis of 207 cases in a Nigerian teaching hospital. Quintessence Int. 2001, 37 (1): 69-74.
21.
go back to reference Buckner A, Sciubba JJ: Peripheral Epithelial Odontogenic Tumours: A review. Oral Surg Oral Med Oral Pathol. 1987, 63: 688-697. 10.1016/0030-4220(87)90372-0.CrossRef Buckner A, Sciubba JJ: Peripheral Epithelial Odontogenic Tumours: A review. Oral Surg Oral Med Oral Pathol. 1987, 63: 688-697. 10.1016/0030-4220(87)90372-0.CrossRef
22.
go back to reference Li TJ, Wu YT, Yu SF, Yu GY: Unicystic ameloblastoma, a clinicopathologic study of 33 chinese patients. Am J Surg Pathol. 2000, 24 (10): 1385-1392.CrossRefPubMed Li TJ, Wu YT, Yu SF, Yu GY: Unicystic ameloblastoma, a clinicopathologic study of 33 chinese patients. Am J Surg Pathol. 2000, 24 (10): 1385-1392.CrossRefPubMed
23.
go back to reference Deshpande A, Umap P, Munshi M: Granular cell ameloblastoma of the jaw. A report of two cases with fine needle aspiration cytology. Acta Cytol. 2000, 44 (1): 81-85.CrossRefPubMed Deshpande A, Umap P, Munshi M: Granular cell ameloblastoma of the jaw. A report of two cases with fine needle aspiration cytology. Acta Cytol. 2000, 44 (1): 81-85.CrossRefPubMed
24.
go back to reference Waldron CA, Small IA, Silverman H: Clear cell ameloblastoma – an odontogenic carcinoma. J Oral Maxillofac Surg. 1985, 43 (9): 707-717.CrossRefPubMed Waldron CA, Small IA, Silverman H: Clear cell ameloblastoma – an odontogenic carcinoma. J Oral Maxillofac Surg. 1985, 43 (9): 707-717.CrossRefPubMed
25.
go back to reference Braunshtein E, Vered M, Taicher S, Buchner A: Clear cell odontogenic carcinoma and clear cell ameloblastoma: a single clinicopathologic entity? A new case and comparative analysis of the literature. J Oral Maxillofac Surg. 2003, 61 (9): 1004-1010. 10.1016/S0278-2391(03)00311-2.CrossRefPubMed Braunshtein E, Vered M, Taicher S, Buchner A: Clear cell odontogenic carcinoma and clear cell ameloblastoma: a single clinicopathologic entity? A new case and comparative analysis of the literature. J Oral Maxillofac Surg. 2003, 61 (9): 1004-1010. 10.1016/S0278-2391(03)00311-2.CrossRefPubMed
Metadata
Title
Clinicopathological analysis of histological variants of ameloblastoma in a suburban Nigerian population
Authors
Kehinde E Adebiyi
Vincent I Ugboko
Ganiat O Omoniyi-Esan
Kizito C Ndukwe
Fadekemi O Oginni
Publication date
01-12-2006
Publisher
BioMed Central
Published in
Head & Face Medicine / Issue 1/2006
Electronic ISSN: 1746-160X
DOI
https://doi.org/10.1186/1746-160X-2-42

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