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01-02-2004 | Poster presentation

Clinically relevant concentrations of beta agonists may stimulate alveolar fluid clearance in acute respiratory distress syndrome

Authors: G Perkins, D McAuley, J Frank, D Thickett, X Fang, M Matthay

Published in: Critical Care | Special Issue 1/2004

Excerpt

Acute respiratory distress syndrome (ARDS) is characterised by the development of noncardiogenic pulmonary oedema leading to refractory hypoxaemia. The early clearance of alveolar oedema is an important determinant of outcome in ARDS. β -agonists have been shown to upregulate alveolar fluid clearance (AFC). The primary aim of this study was to determine the concentration of salbutamol achieved in plasma after treatment with intravenous (IV) salbutamol. A second aim was to determine the concentration of airspace salbutamol required to stimulate AFC in the normal rat lung. …

Rezaiguia S, et al.: J Clin Invest 1997, 99: 325-335.PubMedCentralCrossRefPubMed

Title: Clinically relevant concentrations of beta agonists may stimulate alveolar fluid clearance in acute respiratory distress syndrome
Authors: G Perkins
D McAuley
J Frank
D Thickett
X Fang
M Matthay
Publication date: 01-02-2004
Publisher: BioMed Central
Published in: Critical Care / Issue Special Issue 1/2004
Electronic ISSN: 1364-8535
DOI: https://doi.org/10.1186/cc2500

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Clinically relevant concentrations of beta agonists may stimulate alveolar fluid clearance in acute respiratory distress syndrome

Excerpt

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