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Published in: Annals of Surgical Oncology 12/2010

01-12-2010 | Breast Oncology

Clinical Series of Oncoplastic Mastopexy to Optimize Cosmesis of Large-Volume Resections for Breast Conservation

Authors: J. Bong, MD, J. Parker, PA, R. Clapper, BS, W. Dooley, MD

Published in: Annals of Surgical Oncology | Issue 12/2010

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Abstract

Background

Oncoplastic mastopexy has been popularized as a method to hide the cosmetic effects of central or large-volume resections associated with breast conservation surgery for breast cancer.

Materials and Methods

This review was undertaken to study the uses and limitations of these techniques in providing adequate breast conservation lumpectomy for breast cancer of any stage in a single surgeon’s practice. A review of breast cancer cases March 2004 through December 2009 were analyzed for the use of oncoplastic reconstruction in breast conservation surgery.

Results

A total of 167 patients had lumpectomies during this period associated with oncoplastic mastopexy reconstruction. The average age was 55.6 years with a range of 33–85 years. Stage 0 breast cancer accounted for 33 cases (19.8%), and 134 cases were invasive cancers stages 1–3 (stage 1, 34.1%; stage 2, 30.6%; and stage 3, 15.6%). The most common oncoplastic techniques used were, in order of frequency: batwing mastopexy, parallelogram mastopexy, and Modified Wise pattern mastopexy. Positive or close margins (≤2 mm) were present in 37 of 167 cases (22%). Positive margins were most associated with higher stage, positive nodes, positive lymphovascular invasion (LVI), use of neoadjuvant chemotherapy, and larger initial T stage, positive estrogen receptor (ER), and younger age. Of these higher stage, node positive, and use of neoadjuvant chemotherapy were statistically significant in this small series (P values = 0.034, 0.016, and 0.022, respectively). Ki-67 and HER2 status were not associated with positive margins. Positive margins were manageable by local re-excision of a solitary face of the prior resection wall in more than 2/3 of cases to achieve negative pathologic margins. Only 11 of 167 required mastectomy because of failure to achieve adequate margins for oncologic control.

Conclusions

Oncoplastic mastopexy allows the surgeon to address large tumors or tumors in cosmetically difficult sites adequately for breast conservation. Careful margin marking and re-excision of close or positive margins is still often feasible to achieve adequate negative margin with acceptable cosmesis in spite of the large initial volumes of resection.
Literature
1.
go back to reference Anderson BO, Mayetta R, Silverstein MJ. Oncoplastic approaches to partial mastectomy: an overview of volume-displacement techniques. Lancet Oncol. 2005;6:145–57.CrossRefPubMed Anderson BO, Mayetta R, Silverstein MJ. Oncoplastic approaches to partial mastectomy: an overview of volume-displacement techniques. Lancet Oncol. 2005;6:145–57.CrossRefPubMed
2.
go back to reference Clough KB, Lewis Js, Couturaud B, Fitoussi A, Nos C, Falcou MC. Oncoplastic techniques allow extensive resections for breast-conserving therapy of breast carcinomas. Ann Surg. 2003;237:26–34.CrossRefPubMed Clough KB, Lewis Js, Couturaud B, Fitoussi A, Nos C, Falcou MC. Oncoplastic techniques allow extensive resections for breast-conserving therapy of breast carcinomas. Ann Surg. 2003;237:26–34.CrossRefPubMed
3.
go back to reference Horner GM, Shrank P, Moser F, Wagner E, Wayans W. Oncoplastic techniques allow breast-conserving treatment in centrally located breast cancers. Plast Reconstr Surg. 2007;120:390–8.CrossRef Horner GM, Shrank P, Moser F, Wagner E, Wayans W. Oncoplastic techniques allow breast-conserving treatment in centrally located breast cancers. Plast Reconstr Surg. 2007;120:390–8.CrossRef
4.
go back to reference Association of Breast Surgery at BASO, Association of Breast Surgery at BAPRAS, Training Interface Group in Breast Surgery, Baildam A, Bishop H, Boland G, et al. Oncoplastic breast surgery—a guide to good practice. Eur J Surg Oncol. 2007;33 Suppl 1:S1–23. Association of Breast Surgery at BASO, Association of Breast Surgery at BAPRAS, Training Interface Group in Breast Surgery, Baildam A, Bishop H, Boland G, et al. Oncoplastic breast surgery—a guide to good practice. Eur J Surg Oncol. 2007;33 Suppl 1:S1–23.
5.
go back to reference Franceschini G, Magno S, Fabbri C, Chiesa F, Di Leone A, Moschella F, et al. Conservative and radical oncoplastic approaches in the surgical treatment of breast cancer. Eur Rev Med Pharmacol Sci. 2008;12:387–96.PubMed Franceschini G, Magno S, Fabbri C, Chiesa F, Di Leone A, Moschella F, et al. Conservative and radical oncoplastic approaches in the surgical treatment of breast cancer. Eur Rev Med Pharmacol Sci. 2008;12:387–96.PubMed
6.
go back to reference Regano S, Hernanz F, Ortega E, Redondo-Figuero C, Gomez-Fleitas M. Oncoplastic techniques extend breast-conserving surgery to patients with neoadjuvant chemotherapy response unfit for conventional techniques. Surg. 2009;33:2082–6. Regano S, Hernanz F, Ortega E, Redondo-Figuero C, Gomez-Fleitas M. Oncoplastic techniques extend breast-conserving surgery to patients with neoadjuvant chemotherapy response unfit for conventional techniques. Surg. 2009;33:2082–6.
7.
go back to reference Song HM, Styblo TM, Carlson GW, Losken A. The use of oncoplastic reduction techniques to reconstruct partial mastectomy defects in women with ductal carcinoma in situ. Breast J. 2010;16:141–6.CrossRefPubMed Song HM, Styblo TM, Carlson GW, Losken A. The use of oncoplastic reduction techniques to reconstruct partial mastectomy defects in women with ductal carcinoma in situ. Breast J. 2010;16:141–6.CrossRefPubMed
8.
go back to reference Almasad JK, Salah B. Breast reconstruction by local flaps after conserving surgery for breast cancer: an added asset to oncoplastic techniques. Breast J. 2008;14:340–4.CrossRefPubMed Almasad JK, Salah B. Breast reconstruction by local flaps after conserving surgery for breast cancer: an added asset to oncoplastic techniques. Breast J. 2008;14:340–4.CrossRefPubMed
9.
go back to reference Losken A, Styblo TM, Carlson GW, Jones GE, Amerson BJ. Management algorithm and outcome evaluation of partial mastectomy defects treated using reduction or mastepexy techniques. Ann Plast Surg. 2007;59:235–42.CrossRefPubMed Losken A, Styblo TM, Carlson GW, Jones GE, Amerson BJ. Management algorithm and outcome evaluation of partial mastectomy defects treated using reduction or mastepexy techniques. Ann Plast Surg. 2007;59:235–42.CrossRefPubMed
10.
go back to reference Kronowitz SJ, Kuerer HM, Buchholz TA, Valero V, Hunt KK. A management algorithm and practical oncoplastic surgical techniques for repairing partial mastectomy defects. Plast Reconstr Surg. 2008;122:1631–47.CrossRefPubMed Kronowitz SJ, Kuerer HM, Buchholz TA, Valero V, Hunt KK. A management algorithm and practical oncoplastic surgical techniques for repairing partial mastectomy defects. Plast Reconstr Surg. 2008;122:1631–47.CrossRefPubMed
11.
go back to reference Hamdi M, Sinove Y, DePypere H, Van Den Broucke R, Vakaet L, Cocquyt V, et al. The role of oncoplastic surgery in breast cancer. Acta Chir Belg. 2008;108:666–72.PubMed Hamdi M, Sinove Y, DePypere H, Van Den Broucke R, Vakaet L, Cocquyt V, et al. The role of oncoplastic surgery in breast cancer. Acta Chir Belg. 2008;108:666–72.PubMed
12.
go back to reference Clough KB, Kaufman GJ, Nos C, Buccimazza I, Sarfati IM. Improving breast cancer surgery: a classification and quadrant per quadrant atlas for oncoplastic surgery. Ann Surg Oncol. 2010;17:1375–91.CrossRefPubMed Clough KB, Kaufman GJ, Nos C, Buccimazza I, Sarfati IM. Improving breast cancer surgery: a classification and quadrant per quadrant atlas for oncoplastic surgery. Ann Surg Oncol. 2010;17:1375–91.CrossRefPubMed
13.
go back to reference Kaur N, Petit JY, Rietjens M, Maffini F, Luini A, Gatti G, Rey PC, et al. Comparative study of surgical margins in oncoplastic surgery and quadrantectomy in breast cancer. Ann Surg Oncol. 2005;12:539–45.CrossRefPubMed Kaur N, Petit JY, Rietjens M, Maffini F, Luini A, Gatti G, Rey PC, et al. Comparative study of surgical margins in oncoplastic surgery and quadrantectomy in breast cancer. Ann Surg Oncol. 2005;12:539–45.CrossRefPubMed
14.
go back to reference Hoffmann J, Wallwiener D. Classifying breast cancer surgery: a novel, complexity-based system for oncological, oncoplastic and reconstructive procedures, and proof of principle by analysis of 1225 operations in 1166 patients. BMC Cancer. 2009;9:108.CrossRefPubMed Hoffmann J, Wallwiener D. Classifying breast cancer surgery: a novel, complexity-based system for oncological, oncoplastic and reconstructive procedures, and proof of principle by analysis of 1225 operations in 1166 patients. BMC Cancer. 2009;9:108.CrossRefPubMed
15.
go back to reference Chan SW, Chueng PS, Lam SH. Cosmetic outcome and percentage of breast volume excision in oncoplastic breast conserving surgery. World J Surg. 2009 Nov 23 [Epub ahead of print]. Chan SW, Chueng PS, Lam SH. Cosmetic outcome and percentage of breast volume excision in oncoplastic breast conserving surgery. World J Surg. 2009 Nov 23 [Epub ahead of print].
16.
go back to reference Fitoussi AD, Berry MG, Fama F, Falcou MC, Curnier A, Couturaud B, et al. Oncoplastic breast surgery for cancer: Analysis of 540 consecutive cases (outcomes article). Plast Reconstr Surg. 2010;125:454–62.CrossRefPubMed Fitoussi AD, Berry MG, Fama F, Falcou MC, Curnier A, Couturaud B, et al. Oncoplastic breast surgery for cancer: Analysis of 540 consecutive cases (outcomes article). Plast Reconstr Surg. 2010;125:454–62.CrossRefPubMed
17.
go back to reference Dooley WC, Parker J. Understanding the mechanisms creating false positive lumpectomy margins. Am J Surg. 2005;190:606–8.CrossRefPubMed Dooley WC, Parker J. Understanding the mechanisms creating false positive lumpectomy margins. Am J Surg. 2005;190:606–8.CrossRefPubMed
18.
go back to reference Chang YC, Parker J, Dooley WC. Routine operative breast endoscopy reduces local failure in early stage breast cancer. Ann Surg Oncol. 2007;14(2):45–45, Suppl S. Chang YC, Parker J, Dooley WC. Routine operative breast endoscopy reduces local failure in early stage breast cancer. Ann Surg Oncol. 2007;14(2):45–45, Suppl S.
Metadata
Title
Clinical Series of Oncoplastic Mastopexy to Optimize Cosmesis of Large-Volume Resections for Breast Conservation
Authors
J. Bong, MD
J. Parker, PA
R. Clapper, BS
W. Dooley, MD
Publication date
01-12-2010
Publisher
Springer-Verlag
Published in
Annals of Surgical Oncology / Issue 12/2010
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-010-1140-y

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