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Published in: Pediatric Nephrology 1/2013

Open Access 01-01-2013 | Review

Clinical practice recommendations for the treatment of Alport syndrome: a statement of the Alport Syndrome Research Collaborative

Authors: Clifford E. Kashtan, Jie Ding, Martin Gregory, Oliver Gross, Laurence Heidet, Bertrand Knebelmann, Michelle Rheault, Christoph Licht

Published in: Pediatric Nephrology | Issue 1/2013

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Abstract

We present clinical practice recommendations for the treatment of children with Alport syndrome who are not enrolled in clinical trials. Our goal is to promote early initiation of a standard therapeutic approach that will facilitate assessment of the safety and efficacy of the protocol. The treatment protocol is based on the reduction of proteinuria, intraglomerular pressure, and renal fibrosis via interference with the renin–angiotensin–aldosterone system.
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Metadata
Title
Clinical practice recommendations for the treatment of Alport syndrome: a statement of the Alport Syndrome Research Collaborative
Authors
Clifford E. Kashtan
Jie Ding
Martin Gregory
Oliver Gross
Laurence Heidet
Bertrand Knebelmann
Michelle Rheault
Christoph Licht
Publication date
01-01-2013
Publisher
Springer-Verlag
Published in
Pediatric Nephrology / Issue 1/2013
Print ISSN: 0931-041X
Electronic ISSN: 1432-198X
DOI
https://doi.org/10.1007/s00467-012-2138-4

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