Skip to main content
Top
Published in: Implementation Science 1/2017

Open Access 01-12-2017 | Systematic review

Clinical practice guidelines for the management of chronic musculoskeletal pain in primary healthcare: a systematic review

Authors: Dawn V. Ernstzen, Quinette A. Louw, Susan L. Hillier

Published in: Implementation Science | Issue 1/2017

Login to get access

Abstract

Background

Up-to-date, high quality, evidence-based clinical practice guidelines (CPGs) that are applicable for primary healthcare are vital to optimize services for the population with chronic musculoskeletal pain (CMSP). The study aimed to systematically identify and appraise the available evidence-based CPGs for the management of CMSP in adults presenting in primary healthcare settings.

Methods

A systematic review was conducted. Twelve guideline clearinghouses and six electronic databases were searched for eligible CPGs published between the years 2000 and May 2015. CPGs meeting the inclusion criteria were appraised by three reviewers using the Appraisal of Guidelines Research and Evaluation (AGREE) II.

Results

Of the 1082 records identified, 34 were eligible, and 12 CPGs were included based on the inclusion and exclusion criteria. The methodological rigor of CPG development was highly variable, and the median domain score was 66%. The median score for stakeholder involvement was 64%. The lowest median score was obtained for the domain applicability (48%). There was inconsistent use of frameworks to aggregate the level of evidence and the strength of the recommendation in the included CPGs. The scope and content of the included CPGs focussed on opioid prescription.

Conclusion

Numerous CPGs that are applicable for the primary healthcare of CMSP exists, varying in their scope and methodological quality. This study highlights specific elements to enhance the development and reporting of CPGs, which may play a role in the uptake of guidelines into clinical practice. These elements include enhanced reporting of methodological aspects, the use of frameworks to enhance decision making processes, the inclusion of patient preferences and values, and the consideration of factors influencing applicability of recommendations.

Trial registration

PROSPERO CRD42015022098.
Appendix
Available only for authorised users
Literature
2.
go back to reference Foster NE, Pincus T, Underwood MR, Vogel S, Breen A, Harding G. Understanding the care for musculoskeletal conditions – why a biomedical process is inadequate. Rheumatology. 2003;42:401–3.PubMed Foster NE, Pincus T, Underwood MR, Vogel S, Breen A, Harding G. Understanding the care for musculoskeletal conditions – why a biomedical process is inadequate. Rheumatology. 2003;42:401–3.PubMed
3.
4.
go back to reference Rauf WN, Meyer HP, Marcus TS, Becker PJ. The impact of chronic pain on the quality of life of patients attending primary healthcare clinics. S Afr J Anaesth Analg. 2014;20(2):122–6. Rauf WN, Meyer HP, Marcus TS, Becker PJ. The impact of chronic pain on the quality of life of patients attending primary healthcare clinics. S Afr J Anaesth Analg. 2014;20(2):122–6.
5.
go back to reference Scascighini L, Toma V, Dober-Spielmann S, Sprott H. Multidisciplinary treatment for chronic pain: a systematic review of interventions and outcomes. Rheumatology. 2008;47(5):670–8.CrossRefPubMed Scascighini L, Toma V, Dober-Spielmann S, Sprott H. Multidisciplinary treatment for chronic pain: a systematic review of interventions and outcomes. Rheumatology. 2008;47(5):670–8.CrossRefPubMed
6.
go back to reference Harstall C, Ospina M. How prevalent is chronic pain? Pain Clin Update. 2003;11:1–4.CrossRef Harstall C, Ospina M. How prevalent is chronic pain? Pain Clin Update. 2003;11:1–4.CrossRef
11.
go back to reference Rauf WN, Meyer HP, Marcus TS, Becker PJ. Prevalence of chronic pain in patients attending primary healthcare facilities in South-West Tshwane. S Afr Fam Pract. 2013;55(1):85–9.CrossRef Rauf WN, Meyer HP, Marcus TS, Becker PJ. Prevalence of chronic pain in patients attending primary healthcare facilities in South-West Tshwane. S Afr Fam Pract. 2013;55(1):85–9.CrossRef
12.
go back to reference Gagliardi AR, Brouwers MC, Palda VA, Lemieux-Charles L, Grimshaw JM. How can we improve guideline use? A conceptual framework of implementability. Implement Sci. 2011;6:26.CrossRefPubMedPubMedCentral Gagliardi AR, Brouwers MC, Palda VA, Lemieux-Charles L, Grimshaw JM. How can we improve guideline use? A conceptual framework of implementability. Implement Sci. 2011;6:26.CrossRefPubMedPubMedCentral
14.
go back to reference Chou R. Using evidence in pain practice: part II using evidence in pain practice. Pain Med. 2008;14(9):531–41. Chou R. Using evidence in pain practice: part II using evidence in pain practice. Pain Med. 2008;14(9):531–41.
15.
go back to reference Shekelle P, Woolf S, Grimshaw JM, Schünemann HJ, Eccles MP. Developing clinical practice guidelines: reviewing, reporting, and publishing guidelines; updating guidelines; and the emerging issues of enhancing guideline implementability and accounting for comorbid conditions in guideline development. Implement Sci. 2012;7:62.CrossRefPubMedPubMedCentral Shekelle P, Woolf S, Grimshaw JM, Schünemann HJ, Eccles MP. Developing clinical practice guidelines: reviewing, reporting, and publishing guidelines; updating guidelines; and the emerging issues of enhancing guideline implementability and accounting for comorbid conditions in guideline development. Implement Sci. 2012;7:62.CrossRefPubMedPubMedCentral
16.
go back to reference Shaneyfelt TM, Mayo-Smith MF, Rothwangl J. Are guidelines following guidelines? The methodological quality of clinical practice guidelines in the peer-reviewed medical literature. JAMA. 1999;281(20):1900–5.CrossRefPubMed Shaneyfelt TM, Mayo-Smith MF, Rothwangl J. Are guidelines following guidelines? The methodological quality of clinical practice guidelines in the peer-reviewed medical literature. JAMA. 1999;281(20):1900–5.CrossRefPubMed
17.
go back to reference Graham ID, Harrison M, Brouwers M, Davies BL, Dunn S. Facilitating the use of evidence in practice: evaluating and adapting clinical practice guidelines for local use by health care organisations. J Obstet Gynecol Neonatal Nurs. 2002;31:599–611. doi:10.1177/088421702237744.CrossRefPubMed Graham ID, Harrison M, Brouwers M, Davies BL, Dunn S. Facilitating the use of evidence in practice: evaluating and adapting clinical practice guidelines for local use by health care organisations. J Obstet Gynecol Neonatal Nurs. 2002;31:599–611. doi:10.​1177/​088421702237744.CrossRefPubMed
18.
go back to reference Vlayen J, Aertgeerts B, Hannes K, Sermeus W, Ramaekers D. A systematic review of appraisal tools for clinical practice guidelines: multiple similarities and one common deficit. Int J Qual Health Care. 2005;17(3):235–42.CrossRefPubMed Vlayen J, Aertgeerts B, Hannes K, Sermeus W, Ramaekers D. A systematic review of appraisal tools for clinical practice guidelines: multiple similarities and one common deficit. Int J Qual Health Care. 2005;17(3):235–42.CrossRefPubMed
19.
go back to reference Harrison MB, Legare F, Graham ID, Fervers B. Adapting clinical practice guidelines to local context and assessing barriers to their use. CMAJ. 2010;182(2):e78–84.CrossRefPubMedPubMedCentral Harrison MB, Legare F, Graham ID, Fervers B. Adapting clinical practice guidelines to local context and assessing barriers to their use. CMAJ. 2010;182(2):e78–84.CrossRefPubMedPubMedCentral
20.
go back to reference Qaseem A, Forland F, Macbeth F, Ollenschlager G, Philips S, Van der Wees P. On behalf of the Board of trustees of the Guidelines International Network. Guidelines International Network: toward international standards for clinical practice guidelines. Ann Intern Med. 2012;156(7):525–32.CrossRefPubMed Qaseem A, Forland F, Macbeth F, Ollenschlager G, Philips S, Van der Wees P. On behalf of the Board of trustees of the Guidelines International Network. Guidelines International Network: toward international standards for clinical practice guidelines. Ann Intern Med. 2012;156(7):525–32.CrossRefPubMed
21.
go back to reference Woolf SH, Grol R, Hutchinson A, Eccles M, Grimshaw J. Potential benefits, limitations, and harms of clinical guidelines. BMJ. 1999;318:20.CrossRef Woolf SH, Grol R, Hutchinson A, Eccles M, Grimshaw J. Potential benefits, limitations, and harms of clinical guidelines. BMJ. 1999;318:20.CrossRef
22.
go back to reference Brouwers M, Kho ME, Browman GP, Burgers JS, Cluzeau F, Feder G, Fervers B, Graham ID, Grimshaw J, Hanna S, Littlejohns P, Makarski J. Zitzelsberger L for the AGREE Next Steps Consortium. AGREE II: advancing guideline development, reporting and evaluation in healthcare. CMAJ. 2010;182:E839–842. doi:10.1503/090449.CrossRefPubMedPubMedCentral Brouwers M, Kho ME, Browman GP, Burgers JS, Cluzeau F, Feder G, Fervers B, Graham ID, Grimshaw J, Hanna S, Littlejohns P, Makarski J. Zitzelsberger L for the AGREE Next Steps Consortium. AGREE II: advancing guideline development, reporting and evaluation in healthcare. CMAJ. 2010;182:E839–842. doi:10.​1503/​090449.CrossRefPubMedPubMedCentral
23.
go back to reference Gonzalez-Suarez C, Grimmer-Somers K, Dizon J, King E, Lorenzo S, Valdecanas C, Gambito E, Fidel B. Contextualizing Western guidelines for stroke and low back pain to a developing country (Philippines): an innovative approach to putting evidence into practice efficiently. J Healthc Leadersh. 2012;4:141–56.CrossRef Gonzalez-Suarez C, Grimmer-Somers K, Dizon J, King E, Lorenzo S, Valdecanas C, Gambito E, Fidel B. Contextualizing Western guidelines for stroke and low back pain to a developing country (Philippines): an innovative approach to putting evidence into practice efficiently. J Healthc Leadersh. 2012;4:141–56.CrossRef
26.
go back to reference Kredo T, Gerritsen A, Van Heerden J, Conway S, Siegfried N. Clinical practice guidelines within the Southern African development community: a descriptive study of the quality of guideline development and concordance with best evidence for five priority diseases. Health Res Pol Syst. 2012;10(1). Kredo T, Gerritsen A, Van Heerden J, Conway S, Siegfried N. Clinical practice guidelines within the Southern African development community: a descriptive study of the quality of guideline development and concordance with best evidence for five priority diseases. Health Res Pol Syst. 2012;10(1).
27.
go back to reference Furlan AD, Reardon R, Weppler C. Opioids for chronic noncancer pain: a new Canadian practice guideline. Can Med Assoc J. 2010;182:923–30.CrossRef Furlan AD, Reardon R, Weppler C. Opioids for chronic noncancer pain: a new Canadian practice guideline. Can Med Assoc J. 2010;182:923–30.CrossRef
28.
go back to reference Kahan M, Mailis-Gagnon A, Wilson L, Srivastava A. Canadian guideline for safe and effective use of opioids for chronic noncancer pain cinical summary for family physicians. Part 1: general population. Can Fam Physician. 2011;57:1257–66.PubMedPubMedCentral Kahan M, Mailis-Gagnon A, Wilson L, Srivastava A. Canadian guideline for safe and effective use of opioids for chronic noncancer pain cinical summary for family physicians. Part 1: general population. Can Fam Physician. 2011;57:1257–66.PubMedPubMedCentral
29.
go back to reference Cheung CW, Qiu Q, Choi S, Moore B, Goucke R, Irwin M. Chronic opioid therapy for chronic non-cancer pain: a review and comparison of treatment guidelines. Pain Physician. 2014;17:402–14. Cheung CW, Qiu Q, Choi S, Moore B, Goucke R, Irwin M. Chronic opioid therapy for chronic non-cancer pain: a review and comparison of treatment guidelines. Pain Physician. 2014;17:402–14.
31.
go back to reference Hooten WM, Timming R, Belgrade M, Gaul J, Goertz M, et al. for the Institute for Clinical Systems Improvement. In: Assessment and Management of Chronic Pain. 2013. Hooten WM, Timming R, Belgrade M, Gaul J, Goertz M, et al. for the Institute for Clinical Systems Improvement. In: Assessment and Management of Chronic Pain. 2013.
33.
go back to reference Sanders SH, Harden NR, Vicente PJ. Evidence-based clinical practice guidelines for interdisciplinary rehabilitation of chronic non-malignant pain syndrome patients. Pain Prac. 2005;4(5):303–15.CrossRef Sanders SH, Harden NR, Vicente PJ. Evidence-based clinical practice guidelines for interdisciplinary rehabilitation of chronic non-malignant pain syndrome patients. Pain Prac. 2005;4(5):303–15.CrossRef
34.
go back to reference Misso ML, Pitt VJ, Jones KM, Barnes HN, Piterman L, Green SE. Quality and consistency of CPG for diagnosis and management of osteoarthritis of the hip and knee: a descriptive overview of published guidelines. MJA. 2008;189(7):394–9.PubMed Misso ML, Pitt VJ, Jones KM, Barnes HN, Piterman L, Green SE. Quality and consistency of CPG for diagnosis and management of osteoarthritis of the hip and knee: a descriptive overview of published guidelines. MJA. 2008;189(7):394–9.PubMed
35.
go back to reference Vernooij RWM, Sanabria AJ, Solà I, Alonso-Coello P, Martínez GL. Guidance for updating clinical practice guidelines: a systematic review of methodological handbooks. Implement Sci. 2014;9:3.CrossRefPubMedPubMedCentral Vernooij RWM, Sanabria AJ, Solà I, Alonso-Coello P, Martínez GL. Guidance for updating clinical practice guidelines: a systematic review of methodological handbooks. Implement Sci. 2014;9:3.CrossRefPubMedPubMedCentral
36.
go back to reference Woolf SH, Schünemann HJ, Eccles MP, Grimshaw JM, Shekelle P. Developing clinical practice guidelines: types of evidence and outcomes; values and economics, synthesis, grading, and presentation and deriving recommendations. Implement Sci. 2012;7:61.CrossRefPubMedPubMedCentral Woolf SH, Schünemann HJ, Eccles MP, Grimshaw JM, Shekelle P. Developing clinical practice guidelines: types of evidence and outcomes; values and economics, synthesis, grading, and presentation and deriving recommendations. Implement Sci. 2012;7:61.CrossRefPubMedPubMedCentral
37.
go back to reference Hillier S, Grimmer-Somers K, Merlin T, Middleton P, Salisbury J, Tooher R, Weston A. FORM: an Australian method for grading recommendations in evidence-based clinical guidelines. BMC Med Res Methodol. 2011;11:23.CrossRefPubMedPubMedCentral Hillier S, Grimmer-Somers K, Merlin T, Middleton P, Salisbury J, Tooher R, Weston A. FORM: an Australian method for grading recommendations in evidence-based clinical guidelines. BMC Med Res Methodol. 2011;11:23.CrossRefPubMedPubMedCentral
38.
go back to reference Alonso-Coello P, Oxman AD, Moberg J, Brignardello-Petersen R, Akl EA, Davoli M, Treweek S, Mustafa RA, Vandvik PO, Meerpohl J, Guyatt GH, Schünemann HJ. the GRADE Working Group. GRADE Evidence to Decision (EtD) frameworks: a systematic and transparent approach to making well informed healthcare choices. 2: Clinical practice guidelines. BMJ. 2016;353:i2089. http://dx.doi.org/10.1136/bmj.i2089.CrossRefPubMed Alonso-Coello P, Oxman AD, Moberg J, Brignardello-Petersen R, Akl EA, Davoli M, Treweek S, Mustafa RA, Vandvik PO, Meerpohl J, Guyatt GH, Schünemann HJ. the GRADE Working Group. GRADE Evidence to Decision (EtD) frameworks: a systematic and transparent approach to making well informed healthcare choices. 2: Clinical practice guidelines. BMJ. 2016;353:i2089. http://​dx.​doi.​org/​10.​1136/​bmj.​i2089.CrossRefPubMed
39.
go back to reference Krahn M, Naglie G. The next step in guideline development: incorporating patient preferences. JAMA. 2008;300(4):436–8.CrossRefPubMed Krahn M, Naglie G. The next step in guideline development: incorporating patient preferences. JAMA. 2008;300(4):436–8.CrossRefPubMed
40.
go back to reference Dizon JM, Machingaidze S, Grimmer K. To adopt, to adapt, or to contextualise? The big question in clinical practice guideline development. BMC Res Notes. 2016;9:442.CrossRefPubMedPubMedCentral Dizon JM, Machingaidze S, Grimmer K. To adopt, to adapt, or to contextualise? The big question in clinical practice guideline development. BMC Res Notes. 2016;9:442.CrossRefPubMedPubMedCentral
41.
go back to reference Manchikanti L, Abdi S, Atluri S, Balog CC, et al. American Society of Interventional Pain Physicians (ASIPP) Guidelines for responsible opioid prescribing in chronic non-cancer pain: Part I – evidence assessment Part 2 – Guidance. Pain Physician. 2012;15(Suppl S1-S66):S67–S116.PubMed Manchikanti L, Abdi S, Atluri S, Balog CC, et al. American Society of Interventional Pain Physicians (ASIPP) Guidelines for responsible opioid prescribing in chronic non-cancer pain: Part I – evidence assessment Part 2 – Guidance. Pain Physician. 2012;15(Suppl S1-S66):S67–S116.PubMed
45.
46.
go back to reference Harris GR, Susman JL. Managing musculoskeletal complaints with rehabilitation therapy: summary of the Philadelphia panel evidence-based clinical practice guidelines on musculoskeletal rehabilitation interventions. J Fam Pract. 2002;51(12):1042–46.PubMed Harris GR, Susman JL. Managing musculoskeletal complaints with rehabilitation therapy: summary of the Philadelphia panel evidence-based clinical practice guidelines on musculoskeletal rehabilitation interventions. J Fam Pract. 2002;51(12):1042–46.PubMed
47.
go back to reference The Philadelphia Panel Members and Ottawa Methods Group Philadelphia panel evidence-based clinical practice guidelines on selected rehabilitation interventions: Overview and Methodology. Phys Ther. 2001;81(10):1629 – 40. The Philadelphia Panel Members and Ottawa Methods Group Philadelphia panel evidence-based clinical practice guidelines on selected rehabilitation interventions: Overview and Methodology. Phys Ther. 2001;81(10):1629 – 40.
48.
go back to reference Raff M, Eppel S, Meyer H, Sarembock B, Webb D. South African guideline for the use of chronic opioid therapy for chronic non-cancer pain. S Afr Med J. 2014;104(1 Suppl 1):78–89. doi:10.7196/SAMJ.7316. Raff M, Eppel S, Meyer H, Sarembock B, Webb D. South African guideline for the use of chronic opioid therapy for chronic non-cancer pain. S Afr Med J. 2014;104(1 Suppl 1):78–89. doi:10.​7196/​SAMJ.​7316.
Metadata
Title
Clinical practice guidelines for the management of chronic musculoskeletal pain in primary healthcare: a systematic review
Authors
Dawn V. Ernstzen
Quinette A. Louw
Susan L. Hillier
Publication date
01-12-2017
Publisher
BioMed Central
Published in
Implementation Science / Issue 1/2017
Electronic ISSN: 1748-5908
DOI
https://doi.org/10.1186/s13012-016-0533-0

Other articles of this Issue 1/2017

Implementation Science 1/2017 Go to the issue