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International Orthopaedics

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01-09-2014 | Review Article

Clinical outcomes and complications of a collagen meniscus implant: a systematic review

Authors: Alberto Grassi, Stefano Zaffagnini, Giulio Maria Marcheggiani Muccioli, Andrea Benzi, Maurilio Marcacci

Published in: International Orthopaedics | Issue 9/2014

Abstract

Purpose

The purpose of this systematic review was to summarise and evaluate the clinical outcomes of the collagen meniscus implant (CMI) and its complication and failure rates. These data were then used to evaluate the results of the CMI at different follow-up time periods and investigate possible differences in the behaviour of lateral and medial CMI.

Methods

A comprehensive search was performed in PubMed, MEDLINE, CINAHL, Cochrane, EMBASE and Google Scholar databases using various combinations of the following keywords: “collagen meniscus implant” or “collagen meniscal implant”. All studies evaluating medial or lateral CMI using the Lysholm score, visual analogue scale (VAS) for pain, Tegner activity scale and subjective or objective International Knee Documentation Committee (IKDC) scores were included in the systematic review.

Results

Eleven studies were included in the systematic review. The pooled number of patients involved in CMI surgery were 396 (90.2 % medial, 9.8 % lateral), with a mean age at surgery of 37.8 years. Concomitant procedures were present in 48.8 % of patients; most of them were anterior cruciate ligament (ACL) reconstruction, high tibial osteotomy (HTO) and microfractures. The Lysholm score and VAS for pain showed an improvement at six months up to ten years. No noticeable differences were present comparing short-term values of Lysholm score between medial and lateral CMI. The Tegner activity level reached its peak at 12 months after surgery and showed a progressive decrease through five and ten years post CMI implantation, however always remaining above the pre-operative level. Only a few knees were rated as “nearly abnormal” or “abnormal” at IKDC grading at all follow-up evaluations.

Conclusions

The CMI could produce good and stable clinical results, particularly regarding knee function and pain, with low rates of complications and reoperations.

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Title: Clinical outcomes and complications of a collagen meniscus implant: a systematic review
Authors: Alberto Grassi
Stefano Zaffagnini
Giulio Maria Marcheggiani Muccioli
Andrea Benzi
Maurilio Marcacci
Publication date: 01-09-2014
Publisher: Springer Berlin Heidelberg
Published in: International Orthopaedics / Issue 9/2014
Print ISSN: 0341-2695
Electronic ISSN: 1432-5195
DOI: https://doi.org/10.1007/s00264-014-2408-9

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Clinical outcomes and complications of a collagen meniscus implant: a systematic review

Abstract

Purpose

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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