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Published in: Current Obstetrics and Gynecology Reports 1/2014

01-03-2014 | Management of Gestational Trophoblastic Diseases (A Cheung, Section Editor)

Clinical Epidemiology of Gestational Trophoblastic Disease

Authors: Anna E. Strohl, John R. Lurain

Published in: Current Obstetrics and Gynecology Reports | Issue 1/2014

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Abstract

The epidemiology of gestational trophoblastic disease (GTD) is not well defined. The rarity of the disease and challenges in data collection limit interpretation of incidence data. Incidence of GTD appears to be influenced by geographic region, with the highest rates occurring in Southeast Asia and Japan. Risk factors for molar pregnancy include extremes of maternal age, reproductive history, and dietary deficiencies. Risk factors for choriocarcinoma include age, ethnicity, history of complete molar pregnancy, and ABO blood group status. With improvements in socioeconomic conditions and diet as well as diagnosis and management of GTD, the incidence of trophoblastic disease is declining worldwide. Future studies should focus on mechanisms by which risk factors influence development and progression of GTD.
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Metadata
Title
Clinical Epidemiology of Gestational Trophoblastic Disease
Authors
Anna E. Strohl
John R. Lurain
Publication date
01-03-2014
Publisher
Springer US
Published in
Current Obstetrics and Gynecology Reports / Issue 1/2014
Electronic ISSN: 2161-3303
DOI
https://doi.org/10.1007/s13669-013-0070-7

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