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Published in: BMC Oral Health 1/2021

Open Access 01-12-2021 | Research article

Clinical efficacy of mineralized collagen (MC) versus anorganic bovine bone (Bio-Oss) for immediate implant placement in esthetic area: a single-center retrospective study

Authors: Yan Dai, Jin Xu, Xiao-Hui Han, Fu-Zhai Cui, Dong-Sheng Zhang, Sheng-Yun Huang

Published in: BMC Oral Health | Issue 1/2021

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Abstract

Background

The purpose of this retrospective study was to evaluate the clinical efficacy of mineralized collagen (MC) versus anorganic bovine bone (Bio-Oss) for immediate implant placement in esthetic area.

Methods

Medical records of Department of Oral and Maxillofacial Surgery of Shandong Provincial Hospital were screened for patients who had been treated with immediate implant implantation in the esthetic area using either MC (Allgens®, Beijing Allgens Medical Science and Technology Co., Ltd., China) or Bio-Oss (Bio-Oss®, Geistlich Biomaterials, Wolhusen, Switzerland), between January 2018 and December 2019. All patients fulfilling the in-/exclusion criteria and following followed for a minimum period of 1 year after surgery were enrolled into the presented study. Implant survival rate, radiographic, esthetic and patient satisfactory evaluations were performed.

Results

Altogether, 70 patients were included in the study; a total of 80 implants were inserted. All implants had good initial stability. The survival rate of implants was 100% at 1-year follow-up. The differences in horizontal and vertical bone loss between the MC group (0.72 ± 0.26 mm, 1.62 ± 0.84 mm) and the Bio-Oss group (0.70 ± 0.52 mm, 1.57 ± 0.88 mm) were no significant difference statistically no significant 6 months after permanent restoration. Similar results occurred at 12 months after permanent restoration functional loaded. Clinical acceptability defined by pink esthetic score (PES) ≥ 6 (6.07 ± 1.62 vs. 6.13 ± 1.41) was not significantly different between groups. Patient satisfaction estimated by visual analog scale (VAS) was similar (8.56 ± 1.12 vs. 8.27 ± 1.44), and the difference was no significant difference between the two groups.

Conclusions

The biomimetic MC showed a similar behaviour as Bio-Oss not only in its dimensional tissues changes but also in clinical acceptability and patient satisfaction. Within the limitations of this study, these cases show that MC could be considered as an alternative bone graft in IIP
Literature
1.
go back to reference Hammerle CH, Chen ST, Wilson TG Jr. Consensus statements and recommended clinical procedures regarding the placement of implants in extraction sockets. Int J Oral Maxillofac Implants. 2004;19(Suppl):26–8.PubMed Hammerle CH, Chen ST, Wilson TG Jr. Consensus statements and recommended clinical procedures regarding the placement of implants in extraction sockets. Int J Oral Maxillofac Implants. 2004;19(Suppl):26–8.PubMed
2.
go back to reference Schultz AJ. Guided tissue regeneration (GTR) of nonsubmerged implants in immediate extraction sites. Pract Periodontics Aesthet Dent. 1993;5(2):59–65 (quiz 66).PubMed Schultz AJ. Guided tissue regeneration (GTR) of nonsubmerged implants in immediate extraction sites. Pract Periodontics Aesthet Dent. 1993;5(2):59–65 (quiz 66).PubMed
3.
go back to reference Gelb DA. Immediate implant surgery: three-year retrospective evaluation of 50 consecutive cases. Int J Oral Maxillofac Implants. 1993;8(4):388–99.PubMed Gelb DA. Immediate implant surgery: three-year retrospective evaluation of 50 consecutive cases. Int J Oral Maxillofac Implants. 1993;8(4):388–99.PubMed
4.
go back to reference Rosenquist B, Grenthe B. Immediate placement of implants into extraction sockets: implant survival. Int J Oral Maxillofac Implants. 1996;11(2):205–9.PubMed Rosenquist B, Grenthe B. Immediate placement of implants into extraction sockets: implant survival. Int J Oral Maxillofac Implants. 1996;11(2):205–9.PubMed
5.
go back to reference Schwartz-Arad D, Chaushu G. The ways and wherefores of immediate placement of implants into fresh extraction sites: a literature review. J Periodontol. 1997;68(10):915–23.PubMedCrossRef Schwartz-Arad D, Chaushu G. The ways and wherefores of immediate placement of implants into fresh extraction sites: a literature review. J Periodontol. 1997;68(10):915–23.PubMedCrossRef
6.
go back to reference Becker W, Clokie C, Sennerby L, Urist MR, Becker BE. Histologic findings after implantation and evaluation of different grafting materials and titanium micro screws into extraction sockets: case reports. J Periodontol. 1998;69(4):414–21.PubMedCrossRef Becker W, Clokie C, Sennerby L, Urist MR, Becker BE. Histologic findings after implantation and evaluation of different grafting materials and titanium micro screws into extraction sockets: case reports. J Periodontol. 1998;69(4):414–21.PubMedCrossRef
7.
go back to reference Schwartz-Arad D, Chaushu G. Immediate implant placement: a procedure without incisions. J Periodontol. 1998;69(7):743–50.PubMedCrossRef Schwartz-Arad D, Chaushu G. Immediate implant placement: a procedure without incisions. J Periodontol. 1998;69(7):743–50.PubMedCrossRef
8.
go back to reference Wilson TG Jr, Schenk R, Buser D, Cochran D. Implants placed in immediate extraction sites: a report of histologic and histometric analyses of human biopsies. Int J Oral Maxillofac Implants. 1998;13(3):333–41.PubMed Wilson TG Jr, Schenk R, Buser D, Cochran D. Implants placed in immediate extraction sites: a report of histologic and histometric analyses of human biopsies. Int J Oral Maxillofac Implants. 1998;13(3):333–41.PubMed
9.
go back to reference Cornelini R, Scarano A, Covani U, Petrone G, Piattelli A. Immediate one-stage postextraction implant: a human clinical and histologic case report. Int J Oral Maxillofac Implants. 2000;15(3):432–7.PubMed Cornelini R, Scarano A, Covani U, Petrone G, Piattelli A. Immediate one-stage postextraction implant: a human clinical and histologic case report. Int J Oral Maxillofac Implants. 2000;15(3):432–7.PubMed
10.
go back to reference Kan JY, Rungcharassaeng K. Immediate placement and provisionalization of maxillary anterior single implants: a surgical and prosthodontic rationale. Pract Periodontics Aesthet Dent. 2000;12(9):817–24 (quiz 826).PubMed Kan JY, Rungcharassaeng K. Immediate placement and provisionalization of maxillary anterior single implants: a surgical and prosthodontic rationale. Pract Periodontics Aesthet Dent. 2000;12(9):817–24 (quiz 826).PubMed
11.
go back to reference Rosenquist B, Ahmed M. The immediate replacement of teeth by dental implants using homologous bone membranes to seal the sockets: clinical and radiographic findings. Clin Oral Implant Res. 2000;11(6):572–82.CrossRef Rosenquist B, Ahmed M. The immediate replacement of teeth by dental implants using homologous bone membranes to seal the sockets: clinical and radiographic findings. Clin Oral Implant Res. 2000;11(6):572–82.CrossRef
12.
go back to reference Schwartz-Arad D, Gulayev N, Chaushu G. Immediate versus non-immediate implantation for full-arch fixed reconstruction following extraction of all residual teeth: a retrospective comparative study. J Periodontol. 2000;71(6):923–8.PubMedCrossRef Schwartz-Arad D, Gulayev N, Chaushu G. Immediate versus non-immediate implantation for full-arch fixed reconstruction following extraction of all residual teeth: a retrospective comparative study. J Periodontol. 2000;71(6):923–8.PubMedCrossRef
13.
go back to reference Paolantonio M, Dolci M, Scarano A, et al. Immediate implantation in fresh extraction sockets. A controlled clinical and histological study in man. J Periodontol. 2001;72(11):1560–71.PubMedCrossRef Paolantonio M, Dolci M, Scarano A, et al. Immediate implantation in fresh extraction sockets. A controlled clinical and histological study in man. J Periodontol. 2001;72(11):1560–71.PubMedCrossRef
14.
go back to reference Schultes G, Gaggl A. Histologic evaluation of immediate versus delayed placement of implants after tooth extraction. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2001;92(1):17–22.PubMedCrossRef Schultes G, Gaggl A. Histologic evaluation of immediate versus delayed placement of implants after tooth extraction. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2001;92(1):17–22.PubMedCrossRef
15.
go back to reference den Hartog L, Slater JJ, Vissink A, Meijer HJ, Raghoebar GM. Treatment outcome of immediate, early and conventional single-tooth implants in the aesthetic zone: a systematic review to survival, bone level, soft-tissue, aesthetics and patient satisfaction. J Clin Periodontol. 2008;35(12):1073–86.CrossRef den Hartog L, Slater JJ, Vissink A, Meijer HJ, Raghoebar GM. Treatment outcome of immediate, early and conventional single-tooth implants in the aesthetic zone: a systematic review to survival, bone level, soft-tissue, aesthetics and patient satisfaction. J Clin Periodontol. 2008;35(12):1073–86.CrossRef
16.
go back to reference Esposito M, Grusovin MG, Polyzos IP, Felice P, Worthington HV. 2010) Interventions for replacing missing teeth: dental implants in fresh extraction sockets (immediate, immediate-delayed and delayed implants. Cochrane Database Syst Rev. 2010;9:CD005968. Esposito M, Grusovin MG, Polyzos IP, Felice P, Worthington HV. 2010) Interventions for replacing missing teeth: dental implants in fresh extraction sockets (immediate, immediate-delayed and delayed implants. Cochrane Database Syst Rev. 2010;9:CD005968.
17.
go back to reference Chen ST, Buser D. Clinical and esthetic outcomes of implants placed in postextraction sites. Int J Oral Maxillofac Implants. 2009;24(Suppl):186–217.PubMed Chen ST, Buser D. Clinical and esthetic outcomes of implants placed in postextraction sites. Int J Oral Maxillofac Implants. 2009;24(Suppl):186–217.PubMed
18.
go back to reference Esposito M, Grusovin MG, Polyzos IP, Felice P, Worthington HV. Timing of implant placement after tooth extraction: immediate, immediate-delayed or delayed implants? A cochrane systematic review. Eur J Oral Implantol. 2010;3(3):189–205.PubMed Esposito M, Grusovin MG, Polyzos IP, Felice P, Worthington HV. Timing of implant placement after tooth extraction: immediate, immediate-delayed or delayed implants? A cochrane systematic review. Eur J Oral Implantol. 2010;3(3):189–205.PubMed
19.
go back to reference Tarnow DP, Chu SJ, Salama MA, et al. Flapless postextraction socket implant placement in the esthetic zone: part 1. The effect of bone grafting and/or provisional restoration on facial-palatal ridge dimensional change—a retrospective cohort study. Int J Periodontics Restorative Dent. 2014;34(3):323–31.PubMedCrossRef Tarnow DP, Chu SJ, Salama MA, et al. Flapless postextraction socket implant placement in the esthetic zone: part 1. The effect of bone grafting and/or provisional restoration on facial-palatal ridge dimensional change—a retrospective cohort study. Int J Periodontics Restorative Dent. 2014;34(3):323–31.PubMedCrossRef
20.
go back to reference Urban IA, Jovanovic SA, Lozada JL. Vertical ridge augmentation using guided bone regeneration (GBR) in three clinical scenarios prior to implant placement: a retrospective study of 35 patients 12 to 72 months after loading. Int J Oral Maxillofac Implants. 2009;24(3):502–10.PubMed Urban IA, Jovanovic SA, Lozada JL. Vertical ridge augmentation using guided bone regeneration (GBR) in three clinical scenarios prior to implant placement: a retrospective study of 35 patients 12 to 72 months after loading. Int J Oral Maxillofac Implants. 2009;24(3):502–10.PubMed
21.
go back to reference Al Yafi F, Alchawaf B, Nelson K. What is the optimum for alveolar ridge preservation? Dent Clin North Am. 2019;63(3):399–418.PubMedCrossRef Al Yafi F, Alchawaf B, Nelson K. What is the optimum for alveolar ridge preservation? Dent Clin North Am. 2019;63(3):399–418.PubMedCrossRef
22.
go back to reference Wallace SC, Snyder MB, Prasad H. Postextraction ridge preservation and augmentation with mineralized allograft with or without recombinant human platelet-derived growth factor BB (rhPDGF-BB): a consecutive case series. Int J Periodontics Restorative Dent. 2013;33(5):599–609.PubMedCrossRef Wallace SC, Snyder MB, Prasad H. Postextraction ridge preservation and augmentation with mineralized allograft with or without recombinant human platelet-derived growth factor BB (rhPDGF-BB): a consecutive case series. Int J Periodontics Restorative Dent. 2013;33(5):599–609.PubMedCrossRef
23.
go back to reference Hammerle CH, Araujo MG, Simion M, Osteology CG. Evidence-based knowledge on the biology and treatment of extraction sockets. Clin Oral Implant Res. 2012;23(Suppl 5):80–2.CrossRef Hammerle CH, Araujo MG, Simion M, Osteology CG. Evidence-based knowledge on the biology and treatment of extraction sockets. Clin Oral Implant Res. 2012;23(Suppl 5):80–2.CrossRef
24.
go back to reference Mardas N, Trullenque-Eriksson A, MacBeth N, Petrie A, Donos N. Does ridge preservation following tooth extraction improve implant treatment outcomes: a systematic review: group 4: therapeutic concepts & methods. Clin Oral Implant Res. 2015;26(Suppl 11):180–201.CrossRef Mardas N, Trullenque-Eriksson A, MacBeth N, Petrie A, Donos N. Does ridge preservation following tooth extraction improve implant treatment outcomes: a systematic review: group 4: therapeutic concepts & methods. Clin Oral Implant Res. 2015;26(Suppl 11):180–201.CrossRef
25.
go back to reference Misawa M, Lindhe J, Araujo MG. The alveolar process following single-tooth extraction: a study of maxillary incisor and premolar sites in man. Clin Oral Implant Res. 2016;27(7):884–9.CrossRef Misawa M, Lindhe J, Araujo MG. The alveolar process following single-tooth extraction: a study of maxillary incisor and premolar sites in man. Clin Oral Implant Res. 2016;27(7):884–9.CrossRef
26.
go back to reference Liao SS, Cui FZ, Zhang W, Feng QL. Hierarchically biomimetic bone scaffold materials: nano-HA/collagen/PLA composite. J Biomed Mater Res B Appl Biomater. 2004;69(2):158–65.PubMedCrossRef Liao SS, Cui FZ, Zhang W, Feng QL. Hierarchically biomimetic bone scaffold materials: nano-HA/collagen/PLA composite. J Biomed Mater Res B Appl Biomater. 2004;69(2):158–65.PubMedCrossRef
27.
go back to reference Peng C, Wang HP, Yan JH, Song TX. Locking system strengthened by biomimetic MC putty for the treatment of osteoporotic proximal humeral fractures. Regen Biomater. 2017;4(5):289–94.PubMedPubMedCentralCrossRef Peng C, Wang HP, Yan JH, Song TX. Locking system strengthened by biomimetic MC putty for the treatment of osteoporotic proximal humeral fractures. Regen Biomater. 2017;4(5):289–94.PubMedPubMedCentralCrossRef
29.
go back to reference Gluckman H, Pontes CC, Du Toit J. Radial plane tooth position and bone wall dimensions in the anterior maxilla: a CBCT classification for immediate implant placement. J Prosthet Dent. 2018;120(1):50–6.PubMedCrossRef Gluckman H, Pontes CC, Du Toit J. Radial plane tooth position and bone wall dimensions in the anterior maxilla: a CBCT classification for immediate implant placement. J Prosthet Dent. 2018;120(1):50–6.PubMedCrossRef
30.
go back to reference Buser D, Chappuis V, Belser UC, Chen S. Implant placement post extraction in esthetic single tooth sites: when immediate, when early, when late? Periodontol 2000. 2017;73(1):84–102.PubMedCrossRef Buser D, Chappuis V, Belser UC, Chen S. Implant placement post extraction in esthetic single tooth sites: when immediate, when early, when late? Periodontol 2000. 2017;73(1):84–102.PubMedCrossRef
31.
go back to reference Buser D, Weber HP, Lang NP. Tissue integration of non-submerged implants. 1-year results of a prospective study with 100 ITI hollow-cylinder and hollow-screw implants. Clin Implants Res. 1990;1(1):33–40.CrossRef Buser D, Weber HP, Lang NP. Tissue integration of non-submerged implants. 1-year results of a prospective study with 100 ITI hollow-cylinder and hollow-screw implants. Clin Implants Res. 1990;1(1):33–40.CrossRef
32.
go back to reference Yang X, Zhou T, Zhou N, Man Y. The thickness of labial bone affects the esthetics of immediate implant placement and provisionalization in the esthetic zone: a prospective cohort study. Clin Implant Dent Relat Res. 2019;21(3):482–91.PubMedCrossRef Yang X, Zhou T, Zhou N, Man Y. The thickness of labial bone affects the esthetics of immediate implant placement and provisionalization in the esthetic zone: a prospective cohort study. Clin Implant Dent Relat Res. 2019;21(3):482–91.PubMedCrossRef
33.
go back to reference Belser UC, Grutter L, Vailati F, Bornstein MM, Weber HP, Buser D. Outcome evaluation of early placed maxillary anterior single-tooth implants using objective esthetic criteria: a cross-sectional, retrospective study in 45 patients with a 2- to 4-year follow-up using pink and white esthetic scores. J Periodontol. 2009;80(1):140–51.PubMedCrossRef Belser UC, Grutter L, Vailati F, Bornstein MM, Weber HP, Buser D. Outcome evaluation of early placed maxillary anterior single-tooth implants using objective esthetic criteria: a cross-sectional, retrospective study in 45 patients with a 2- to 4-year follow-up using pink and white esthetic scores. J Periodontol. 2009;80(1):140–51.PubMedCrossRef
34.
go back to reference Seymour RA, Charlton JE, Phillips ME. An evaluation of dental pain using visual analogue scales and the Mcgill Pain Questionnaire. J Oral Maxillofac Surg. 1983;41(10):643–8.PubMedCrossRef Seymour RA, Charlton JE, Phillips ME. An evaluation of dental pain using visual analogue scales and the Mcgill Pain Questionnaire. J Oral Maxillofac Surg. 1983;41(10):643–8.PubMedCrossRef
35.
go back to reference Spray JR, Black CG, Morris HF, Ochi S. The influence of bone thickness on facial marginal bone response: stage 1 placement through stage 2 uncovering. Ann Periodontol. 2000;5(1):119–28.PubMedCrossRef Spray JR, Black CG, Morris HF, Ochi S. The influence of bone thickness on facial marginal bone response: stage 1 placement through stage 2 uncovering. Ann Periodontol. 2000;5(1):119–28.PubMedCrossRef
36.
go back to reference Ogunsalu C, Ezeokoli C, Archibald A, et al. Comparative study of osteoblastic activity of same implants (Endopore) in the immediate extraction site utilizing single photon emission computerized tomography: peri-implant autogeneous bone grafting with GTR versus no peri-implant bone grafting—experimental study in pig model. West Indian Med J. 2011;60(3):336–9.PubMed Ogunsalu C, Ezeokoli C, Archibald A, et al. Comparative study of osteoblastic activity of same implants (Endopore) in the immediate extraction site utilizing single photon emission computerized tomography: peri-implant autogeneous bone grafting with GTR versus no peri-implant bone grafting—experimental study in pig model. West Indian Med J. 2011;60(3):336–9.PubMed
38.
go back to reference Liao SS, Guan K, Cui FZ, Shi SS, Sun TS. Lumbar spinal fusion with a MC matrix and rhBMP-2 in a rabbit model. Spine. 2003;28(17):1954–60.PubMedCrossRef Liao SS, Guan K, Cui FZ, Shi SS, Sun TS. Lumbar spinal fusion with a MC matrix and rhBMP-2 in a rabbit model. Spine. 2003;28(17):1954–60.PubMedCrossRef
39.
go back to reference Sun Y, Wang C, Chen Q, et al. Effects of the bilayer nano-hydroxyapatite/MC-guided bone regeneration membrane on site preservation in dogs. J Biomater Appl. 2017;32(2):242–56.PubMedCrossRef Sun Y, Wang C, Chen Q, et al. Effects of the bilayer nano-hydroxyapatite/MC-guided bone regeneration membrane on site preservation in dogs. J Biomater Appl. 2017;32(2):242–56.PubMedCrossRef
40.
go back to reference Ghate NS, Cui H. MC artificial bone repair material products used for fusing the podarthral joints with internal fixation—a case report. Regen Biomater. 2017;4(5):295–8.PubMedPubMedCentralCrossRef Ghate NS, Cui H. MC artificial bone repair material products used for fusing the podarthral joints with internal fixation—a case report. Regen Biomater. 2017;4(5):295–8.PubMedPubMedCentralCrossRef
41.
go back to reference Liu FZ, Wang DW, Zhang YJ, et al. Comparison of rabbit rib defect regeneration with and without graft. J Mater Sci Mater Med. 2017;28(1):2.PubMedCrossRef Liu FZ, Wang DW, Zhang YJ, et al. Comparison of rabbit rib defect regeneration with and without graft. J Mater Sci Mater Med. 2017;28(1):2.PubMedCrossRef
42.
go back to reference Wu J, Xu S, Qiu Z, et al. Comparison of human mesenchymal stem cells proliferation and differentiation on poly(methyl methacrylate) bone cements with and without MC incorporation. J Biomater Appl. 2016;30(6):722–31.PubMedCrossRef Wu J, Xu S, Qiu Z, et al. Comparison of human mesenchymal stem cells proliferation and differentiation on poly(methyl methacrylate) bone cements with and without MC incorporation. J Biomater Appl. 2016;30(6):722–31.PubMedCrossRef
43.
go back to reference Piao W, Yao Y, Hao Z, Ju-li P, Fu-zhai C, Ya-juan G. Repair of bone defect by using MC materials and collagen membrane in minipig models. China J Oral Maxillofac Surg. 2017;15(5):408–12. Piao W, Yao Y, Hao Z, Ju-li P, Fu-zhai C, Ya-juan G. Repair of bone defect by using MC materials and collagen membrane in minipig models. China J Oral Maxillofac Surg. 2017;15(5):408–12.
Metadata
Title
Clinical efficacy of mineralized collagen (MC) versus anorganic bovine bone (Bio-Oss) for immediate implant placement in esthetic area: a single-center retrospective study
Authors
Yan Dai
Jin Xu
Xiao-Hui Han
Fu-Zhai Cui
Dong-Sheng Zhang
Sheng-Yun Huang
Publication date
01-12-2021
Publisher
BioMed Central
Published in
BMC Oral Health / Issue 1/2021
Electronic ISSN: 1472-6831
DOI
https://doi.org/10.1186/s12903-021-01752-4

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