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Published in: Critical Care 1/2011

01-02-2011 | Commentary

Clinical correlates of arterial lactate levels in STEMI patients

Authors: Max Harry Weil, Wanchun Tang

Published in: Critical Care | Issue 1/2011

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Abstract

Increases in blood lactate reflect decreases in systemic blood flows associated with low blood flow states characteristic of circulatory shock. Accordingly, the report by Vermeulen and colleagues documents the use of the blood lactate measurement as a prognostic indicator in settings of ST elevation myocardial infarction. That lactate value therefore identified high-risk patients as a complication, often with clinical signs of cardiogenic shock of corresponding severities.
Literature
1.
go back to reference Vermeulen RP, Hoekstra M, vd Horst ICC, van Pelt LJ, Jessurun GAJ, Jaarsma T, van den Heuvel AFM, Zilstra F: Clinical correlates of arterial lactate levels in patients with ST-segment elevation myocardial infarction at admission: a descriptive study. Crit Care. 2010, 14: R164-10.1186/cc9253.PubMedPubMedCentralCrossRef Vermeulen RP, Hoekstra M, vd Horst ICC, van Pelt LJ, Jessurun GAJ, Jaarsma T, van den Heuvel AFM, Zilstra F: Clinical correlates of arterial lactate levels in patients with ST-segment elevation myocardial infarction at admission: a descriptive study. Crit Care. 2010, 14: R164-10.1186/cc9253.PubMedPubMedCentralCrossRef
2.
go back to reference DeGeare VS, Boura JA, Grinnes LL, O'Neill WW, Grines CL: Predictive value of the Killip classification in patients undergoing primary percutaneous coronary intervention for acute myocardial infarction. Am J Cardiol. 2001, 87: 1035-1038. 10.1016/S0002-9149(01)01457-6.PubMedCrossRef DeGeare VS, Boura JA, Grinnes LL, O'Neill WW, Grines CL: Predictive value of the Killip classification in patients undergoing primary percutaneous coronary intervention for acute myocardial infarction. Am J Cardiol. 2001, 87: 1035-1038. 10.1016/S0002-9149(01)01457-6.PubMedCrossRef
3.
go back to reference Afifi AA, Chang PC, Liu VY, Da Luz P, Weil MH, Shubin H: Prognostic indexes in acute myocardial infarction complicated by shock. Am J Cardiol. 1974, 33: 826-832. 10.1016/0002-9149(74)90628-6.PubMedCrossRef Afifi AA, Chang PC, Liu VY, Da Luz P, Weil MH, Shubin H: Prognostic indexes in acute myocardial infarction complicated by shock. Am J Cardiol. 1974, 33: 826-832. 10.1016/0002-9149(74)90628-6.PubMedCrossRef
4.
go back to reference Broder G, Weil MH: Excess lactate: an index of reversibility of shock in human patients. Science. 1964, 143: 1457-1459. 10.1126/science.143.3613.1457.PubMedCrossRef Broder G, Weil MH: Excess lactate: an index of reversibility of shock in human patients. Science. 1964, 143: 1457-1459. 10.1126/science.143.3613.1457.PubMedCrossRef
5.
go back to reference Weil MH, Afifi AA: Experimental and clinical studies on lactate and pyruvate as indicators of the severity of acute circulatory failure (shock). Circulation. 1970, 41: 989-1001.PubMedCrossRef Weil MH, Afifi AA: Experimental and clinical studies on lactate and pyruvate as indicators of the severity of acute circulatory failure (shock). Circulation. 1970, 41: 989-1001.PubMedCrossRef
6.
go back to reference Orringer CE, Eustace JC, Wunch CD, Gardner LB: Natural history of lactic acidosis after grand-mal seizures. A model for the study of an anion-gap acidosis not associated with hyperkalemia. N Engl J Med. 1977, 297: 796-799. 10.1056/NEJM197710132971502.PubMedCrossRef Orringer CE, Eustace JC, Wunch CD, Gardner LB: Natural history of lactic acidosis after grand-mal seizures. A model for the study of an anion-gap acidosis not associated with hyperkalemia. N Engl J Med. 1977, 297: 796-799. 10.1056/NEJM197710132971502.PubMedCrossRef
7.
go back to reference Huckabee WE: Abnormal resting blood lactate: I. The significance of hyperlactatemia in hospitalized patients. Am J Med. 1961, 30: 840-848. 10.1016/0002-9343(61)90171-1.PubMedCrossRef Huckabee WE: Abnormal resting blood lactate: I. The significance of hyperlactatemia in hospitalized patients. Am J Med. 1961, 30: 840-848. 10.1016/0002-9343(61)90171-1.PubMedCrossRef
8.
go back to reference Huckabee WE: Abnormal resting blood lactate: II. Lactic acidosis. Am J Med. 1961, 30: 840-848. 10.1016/0002-9343(61)90172-3.PubMedCrossRef Huckabee WE: Abnormal resting blood lactate: II. Lactic acidosis. Am J Med. 1961, 30: 840-848. 10.1016/0002-9343(61)90172-3.PubMedCrossRef
9.
go back to reference Vincent JL, Dufaye P, Berré J, Lerman M, DeGaute JP, Kahn RJ: Serial lactate determinations during circulatory shock. Crit Care Med. 1983, 11: 449-451. 10.1097/00003246-198306000-00012.PubMedCrossRef Vincent JL, Dufaye P, Berré J, Lerman M, DeGaute JP, Kahn RJ: Serial lactate determinations during circulatory shock. Crit Care Med. 1983, 11: 449-451. 10.1097/00003246-198306000-00012.PubMedCrossRef
10.
go back to reference Mizock BA, Falk JL: Lactic acidosis in critical illness. Crit Care Med. 1992, 20: 80-93. 10.1097/00003246-199201000-00020.PubMedCrossRef Mizock BA, Falk JL: Lactic acidosis in critical illness. Crit Care Med. 1992, 20: 80-93. 10.1097/00003246-199201000-00020.PubMedCrossRef
Metadata
Title
Clinical correlates of arterial lactate levels in STEMI patients
Authors
Max Harry Weil
Wanchun Tang
Publication date
01-02-2011
Publisher
BioMed Central
Published in
Critical Care / Issue 1/2011
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc9383

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