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BMC Neurology
Published in: BMC Neurology 1/2017

Open Access 01-12-2017 | Research article

Clinical characteristics of impulse control and related disorders in Chinese Parkinson’s disease patients

Authors: Yu Zhang, An qi He, Lin Li, Wei Chen, Zhen guo Liu

Published in: BMC Neurology | Issue 1/2017

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Abstract

Background

Impulse control and related disorders (ICRDs) are clinically complications in Parkinson’s disease (PD). However, the clinical characteristics of ICRDs in Chinese PD patients were rarely reported. We aimed to explore the prevalence and the clinical profile of ICRDs in Chinese patients with PD.

Methods

142 Chinese PD patients were consecutively enrolled. The symptoms of ICRDs were assessed with the Questionnaire for Impulsive-Compulsive Disorders. The clinical characteristics of patients with ICRDs and without ICRDs were compared.

Results

ICRDs were present in 31% of our patients. The most common ICRDs were compulsive medication use (11.3%) and punding (9.2%); the least frequent were walkabout (1.4%). Variables independently associated with ICRDs were earlier onset of the disease (≤55 years), severe cognitive impairment (MMSE 10–20), the dose of dopamine agonist (>1 mg/d) and dyskinesia.

Conclusions

ICRDs was commonly found in Chinese PD patients. Earlier onset of the disease, the dose of dopamine agonist, severe cognitive impairment and dyskinesia are independent factors associated with ICRDs. Our results will be benefit for clinicians to assess the risk of developing ICRDs before delivering dopaminergic medication.
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Metadata
Title
Clinical characteristics of impulse control and related disorders in Chinese Parkinson’s disease patients
Authors
Yu Zhang
An qi He
Lin Li
Wei Chen
Zhen guo Liu
Publication date
01-12-2017
Publisher
BioMed Central
Published in
BMC Neurology / Issue 1/2017
Electronic ISSN: 1471-2377
DOI
https://doi.org/10.1186/s12883-017-0874-6

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