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International Urology and Nephrology
Published in: International Urology and Nephrology 1/2010

01-03-2010 | Nephrology - Original Paper

Clinical characteristics and outcomes of rural patients with ESRD in Guangxi, China: one dialysis center experience

Authors: Wenxin Zhang, Zhifeng Gong, Xiaomei Peng, Sheng Tang, Ming Bi, Wentan Huang

Published in: International Urology and Nephrology | Issue 1/2010

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Abstract

Objectives

End-stage renal disease (ESRD) is a serious public health problem in Guangxi, a province of south China. This prospective study evaluated the characteristics and outcome of rural patients with ESRD in a dialysis center of Guangxi, compared with urban patients in the same period.

Methods

A total of 238 patients (96 rural and 142 urban) who enrolled in 2007 was included in this study and followed up for 1 year. Clinical data including patient basic information, clinical parameters, laboratory tests, data associated with dialysis and prognosis were evaluated and compared between rural and urban groups.

Results

Glomerulonephritis was found to be the most common cause of ESRD in all the cohorts studied, with similar rates of 47.9 and 46.5% in the rural and urban patients, respectively. Compared to urban patients, the rural patients had significantly lower prevalence of diabetic nephropathy (8.3 vs. 24.6%, P < 0.001) and higher prevalence of obstructive uropathy (20.8 vs. 3.5%, P < 0.001); the rural patients were overall younger, with poorer financial supports, but with higher rates of late referrals, poorer renal functions as indicated by related laboratory tests including lower levels of GFR, serum hemoglobin, bicarbonate and Kt/V, but higher prevalence of very low GFR, severe metabolic acidosis, severe anemia and hyperkalemia, higher rate of not initiating dialysis, radial artery puncture and mortality. The cardiovascular events were found to be the most common cause of death in both rural and urban groups.

Conclusions

Glomerulonephritis was found to be the most common cause of ESRD in all the studied patients. The rural patients with ESRD in Guangxi had kidney disease in more advanced stage at the time of first visit to a nephrologist and higher rates of mortality after dialysis initiation, compared to urban patients.
Literature
1.
Yang GH, Huang ZJ, Tan J (1996) Priorities of disease control in China-analysis on mortality data of national disease surveillance points system. Zhonghua Liu Xing Bing Xue Za Zhi 17(4):199–202PubMed
2.
Diczfalusy E (1996) The third age, the third world and the third millennium. Contraception 53(1):1–7CrossRefPubMed
3.
Wu Z, Yao C, Zhao D et al (2001) Sino-MONICA project: a collaborative study on trends and determinants in cardiovascular diseases in China. Part I: morbidity and mortality monitoring. Circulation 103:462–468CrossRefPubMed
4.
Yao C, Wu Z, Wu Y (1993) The changing pattern of cardiovascular diseases in China. World Health Stat Q 46:113–118PubMed
5.
Lin SY (2003) Nephrology in China: a great mission and momentous challenge. Kidney Int 83:108–110CrossRef
6.
Bi SH, Cheng LT, Wang T (2008) A survey of chronic kidney disease in a large hospital in China. Ren Fail 30(5):541–545CrossRefPubMed
7.
Zhang L, Zhang P, Wang F et al (2008) Prevalence and factors associated with CKD: a population study from Beijing. Am J Kidney Dis 51(3):373–384CrossRefPubMed
8.
Dialysis and Transplantation Registration Group CSoNCMA (2001) The report about the registration of dialysis and transplantation in China 1999. Chin J Nephrol 17:77–78 [in Chinese]
9.
10.
11.
Lok SH (1995) Market reforms and China’s health care system. Social Science and Medicine 41(8):1065–1072CrossRef
12.
13.
14.
15.
Gong ZF, Tang S, Peng XM et al (2008) The epidemiology characteristics of the uremia patients under maintenance hemodialysis in Guangxi dialysis center from 2006 to 2007. Chin J Nephrol 24(10):765–767 [in Chinese]
16.
Ma YC, Zuo L, Chen JH et al (2006) Modified glomerular filtration rate estimating equation for Chinese patients with chronic kidney disease. J Am Soc Nephrol 17:2937–2944CrossRefPubMed
17.
Bai J (1986) Rural and urban populations of China. Popul Res 3(4):18–28PubMed
18.
Cass A, Cunningham J, Snelling P et al (2003) Late referral to a nephrologist reduces access to renal transplantation. Am J Kidney Dis 42(5):1043–1049CrossRefPubMed
19.
Barsoum RS (2003) End-stage renal disease in North Africa. Kidney Int Suppl 94:S111–S114CrossRef
20.
Plata R, Silva C, Yahuita J et al (2002) The first clinical and epidemiological program on renal disease in Bolivia: a model for prevention and early diagnosis of renal diseases in the developing countries. Nephrol Dial Transplant 13:3034–3036CrossRef
21.
Zhang AH, Zhong H, Tang W et al (2008) Establishing a renal management clinic in China: initiative, challenges, and opportunities. Int Urol Nephrol 40(4):1053–1058CrossRefPubMed
22.
Liu LS, Chen MQ, Zeng GY et al (2002) A forty-year study on hypertension. Acta Acad Med Sin 24:401–408 [in Chinese]
23.
Gao F (2005) The survey of medical service in Guangxi Zhuang autonomous region [M]. Nanning Guangxi 126–281 [in Chinese]
24.
Ratcliffe PJ, Phillips RE, Oliver DV (1984) Late referral for maintenance dialysis. Br Med J 288:441–443CrossRef
25.
Roubicek C, Brunet P, Huiart L et al (2000) Timing of nephrology referral: influence on mortality and morbidity. Am J Kidney Dis 36(1):35–41CrossRefPubMed
26.
Arora P, Obrador GT, Ruthazer R et al (1999) Prevalence, predictors, and consequences of late nephrology referral at a tertiary care center. J Am Soc Nephrol 10:1281–1286PubMed
27.
Vanherweghem JL, Depierreux M, Tielemans C et al (1993) Rapidly progressive interstitial renal fibrosis in young women: association with slimming regimen including Chinese herbs. Lancet 341:387–391CrossRefPubMed
28.
Debelle FD, Vanherweghem JL, Nortier JL (2008) Aristolochic acid nephropathy: a worldwide problem. Kidney Int 74(2):158–169CrossRefPubMed
29.
Yang HY, Lin JL, Chen KH et al (2006) Aristolochic acid-related nephropathy associated with the popular Chinese herb Xi Xin. J Nephrol 19(1):111–114PubMed
30.
Li X, Wang H (2004) Aristolochic acid nephropathy: what we know and what we have to do. Nephrology (Carlton) 9:109–111CrossRef
31.
Lai MN, Lai JN, Chen PC et al (2009) Increased risks of chronic kidney disease associated with prescribed Chinese herbal products suspected to contain aristolochic acid. Nephrology (Carlton) 14(2):227–234CrossRef
32.
Dogan E, Erkoc R, Sayarlioglu H et al (2005) Effects of late referral to a nephrologist in patients with chronic renal failure. Nephrology (Carlton) 10:516–519CrossRef
33.
NKF-K/DOQI clinical practice guidelines for peritoneal dialysis adequacy: update 2000. Am J Kidney Dis 37(1 Suppl 1):S65–S136
34.
Gilmore J (2006) KDOQI clinical practice guidelines and clinical practice recommendations—2006 updates. Nephrol Nurs J 33(5):487–488PubMed
35.
Zuo L, Wang M, Wang HY (2005) Habit of nephrologists in monitoring and treatment of chronic kidney disease in China. Chin J Nephrol 21(3):127–132 [in Chinese]
36.
Zhang AH, Cheng LT, Zhu N et al (2007) Comparison of quality of life and causes of hospitalization between hemodialysis and peritoneal dialysis patients in China. Health Qual Life Outcomes 5:49CrossRefPubMed
37.
38.
Wang H, Yip W, Zhang L, Wang L, Hsiao W (2005) Community based health insurance in poor rural China: the distribution of net benefits. Health Policy Plan 20(6):366–374CrossRefPubMed
39.
40.
World Health Organization (WHO) (2004) Implementing the new cooperative medical schemes in rapidly changing China: issues and options. Office of the World Health Organization Representative in China, Beijing
41.
US Renal Data System (2004) USRDS 2004 annual data report: atlas of end-stage renal disease in the United States, Bethesda, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases
42.
Soucie JM, McClellan WM (1996) Early death in dialysis patients: risk factors and impact on incidence and mortality rates. J Am Soc Nephrol 7:2169–2175PubMed
43.
Zuo L, Wang M (2006) Current status of hemodialysis treatment in Beijing, China. Ethn Dis Spring 16(2 Suppl 2):S2-31-4
44.
Avram MM, Sreedhara R, Fein P et al (2001) Survival on hemodialysis and peritoneal dialysis over 12 years with emphasis on nutritional parameters. Am J Kidney Dis 37(1 Suppl 2):S77–S80CrossRefPubMed
45.
Held PJ, Port FK, Wolfe RA et al (1996) The dose of hemodialysis and patient mortality. Kidney Int 50:550–556CrossRefPubMed
46.
US Renal Data System. USRDS 1997 Annual Data Report (1997) The National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases. Bethesda, MD
47.
Port FK, Wolfe RA, Levin NW et al (1990) Income and survival in chronic dialysis patients. ASAIO Transactions 36:M154–M157PubMed
Metadata
Title
Clinical characteristics and outcomes of rural patients with ESRD in Guangxi, China: one dialysis center experience
Authors
Wenxin Zhang
Zhifeng Gong
Xiaomei Peng
Sheng Tang
Ming Bi
Wentan Huang
Publication date
01-03-2010
Publisher
Springer Netherlands
Published in
International Urology and Nephrology / Issue 1/2010
Print ISSN: 0301-1623
Electronic ISSN: 1573-2584
DOI
https://doi.org/10.1007/s11255-009-9609-y

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