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International Urology and Nephrology

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Open Access 08-12-2023 | Chronic Kidney Disease | Nephrology - Original Paper

Association between the cardiometabolic index and chronic kidney disease: a cross-sectional study

Authors: Qian Guo, Yani Wang, Yuchen Liu, Yun Wang, Lin Deng, Lihua Liao, Xueqin Lin, Mingxin Wu, Meirui Sun, Ying Liao

Published in: International Urology and Nephrology | Issue 5/2024

Abstract

Background

Central obesity is a risk factor for chronic kidney disease (CKD). However, the exact correlation between the cardiometabolic index (CMI), an indicator of central obesity, and CKD remains unclear. Here, we aimed to investigate the correlation between the CMI and CKD in the general American population.

Methods

This cross-sectional study involved 64,313 members of the general population (≥ 20 years of age) with data in the National Health and Nutrition Examination Survey (NHANES) 1999–2020. The individuals were grouped into three categories by CMI tertile: T1 group (n = 7,029), T2 group (n = 7,356), and T3 group (n = 7,380). Logistic regression analysis was performed, with NHANES recommended weights, to assess the association between the CMI and CKD.

Results

A total of 21,765 participants were included; the overall prevalence of CKD was 12.2%. From the low to the high CMI tertile, the prevalence of CKD increased from 8.9% to 16.0% (P < 0.001). After full adjustment for confounders, the higher tertile of CMI (OR: 1.08, 95% CI: 1.03 − 1.13, P = 0.002) had the higher risk of CKD. Compared with the T1 group, the groups with higher CMI levels had a higher CKD risk (T2: OR: 1.01, 95%CI: 0.87–1.18, P = 0.812; T3: OR: 1.22, 95%CI: 1.05–1.43, P = 0.013).

Conclusions

Higher CMI was independently associated with higher CKD risk in the general population.

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Title: Association between the cardiometabolic index and chronic kidney disease: a cross-sectional study
Authors: Qian Guo
Yani Wang
Yuchen Liu
Yun Wang
Lin Deng
Lihua Liao
Xueqin Lin
Mingxin Wu
Meirui Sun
Ying Liao
Publication date: 08-12-2023
Publisher: Springer Netherlands
Keywords: Chronic Kidney Disease
Obesity
Obesity
Published in: International Urology and Nephrology / Issue 5/2024
Print ISSN: 0301-1623
Electronic ISSN: 1573-2584
DOI: https://doi.org/10.1007/s11255-023-03888-4

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