Skip to main content
Top
Published in: Archives of Public Health 1/2024

Open Access 01-12-2024 | Research

Chronic disease and multimorbidity in the Chinese older adults’ population and their impact on daily living ability: a cross-sectional study of the Chinese Longitudinal Healthy Longevity Survey (CLHLS)

Authors: Ye Chen, Huixia Ji, Yang Shen, Dandan Liu

Published in: Archives of Public Health | Issue 1/2024

Login to get access

Abstract

Background

Owing to an increase in life expectancy, it is common for the older adults to suffer from chronic diseases that can result in disability and a low quality of life. This study aimed to explore the influence of chronic diseases and multimorbidities on activities of daily living (ADLs) and instrumental ADLs (IADLs) in an older Chinese population.

Methods

Based on the Chinese Longitudinal Healthy Longevity Survey (2018), 9,155 older adults aged 65 years and above were included in the study. A self-administered questionnaire was used to collect information on demographic characteristics, chronic diseases, ADLs, and IADLs. The impact of factors affecting ADL and IADL impairment in older adults was analysed using binary logistic regression.

Results

In total, 66.3% participants had chronic diseases. Hypertension, heart disease, arthritis, diabetes and cerebrovascular disease were among the top chronic diseases. Of these, 33.7% participants had multimorbidities. The most common combination of the two chronic diseases was hypertension and heart disease (11.2%), whereas the most common combination of the three chronic diseases was hypertension, heart disease, and diabetes (3.18%). After categorising the older adults into four age groups, dementia, visual impairment, and hearing impairment were found to be more prevalent with increasing age. The prevalence of hypertension, heart disease, cerebrovascular disease, gastrointestinal ulcers, arthritis and chronic nephritis gradually increased with age until the age of 75 years, peaked in the 75–84 years age group, and then showed a decreasing trend with age. Multimorbidity prevalence followed a similar pattern. Regression analysis indicated that the increase in age group and the number of chronic diseases independently correlated with impairments in ADL as well as IADL. Additionally, gender, physical activity, educational background, obesity, depressive symptoms, and falls also had an impact on ADLs or IADLs.

Conclusion

Chronic diseases and multimorbidities are common in older adults, and it is important to note that aging, multimorbidity, obesity, and unhealthy lifestyle choices may interfere with ADLs or IADLs in older adults. Therefore, it is imperative that primary healthcare providers pay special attention to older adults and improve screening for multimorbidity and follow-up needs.
Literature
1.
go back to reference Willadsen TG, Siersma V, Nicolaisdottir DR, Jarbol D, Guassora AD, Reventlow S, et al. Symptom burden in multimorbidity: a population-based combined questionnaire and registry study from Denmark. BMJ Open. 2021;11(4):e041877.CrossRefPubMedPubMedCentral Willadsen TG, Siersma V, Nicolaisdottir DR, Jarbol D, Guassora AD, Reventlow S, et al. Symptom burden in multimorbidity: a population-based combined questionnaire and registry study from Denmark. BMJ Open. 2021;11(4):e041877.CrossRefPubMedPubMedCentral
2.
go back to reference Zhou X, Zhang D. Multimorbidity in the Elderly: A Systematic Bibliometric Analysis of Research Output. Int J Environ Res Public Health. 2021;19(1):353.CrossRefPubMedPubMedCentral Zhou X, Zhang D. Multimorbidity in the Elderly: A Systematic Bibliometric Analysis of Research Output. Int J Environ Res Public Health. 2021;19(1):353.CrossRefPubMedPubMedCentral
3.
go back to reference Zeng Y, Feng Q, Hesketh T, Christensen K, Vaupel JW. Survival, disabilities in activities of daily living, and physical and cognitive functioning among the oldest-old in China: a cohort study. Lancet. 2017;389(10079):1619–29.CrossRefPubMedPubMedCentral Zeng Y, Feng Q, Hesketh T, Christensen K, Vaupel JW. Survival, disabilities in activities of daily living, and physical and cognitive functioning among the oldest-old in China: a cohort study. Lancet. 2017;389(10079):1619–29.CrossRefPubMedPubMedCentral
5.
go back to reference Zeng Y, Xiao ZY, Zhang CY, Liu YZ, Zhan J, Jin WB. The 1998 Healthy Longevity Survey and the Active Life Expectancy of the Oldest Old in China. Chinese Journal Of Population Science. 2001;3:9–16. Zeng Y, Xiao ZY, Zhang CY, Liu YZ, Zhan J, Jin WB. The 1998 Healthy Longevity Survey and the Active Life Expectancy of the Oldest Old in China. Chinese Journal Of Population Science. 2001;3:9–16.
6.
go back to reference Andresen EM, Malmgren JA, Carter WB, Patrick DL. Screening for depression in well older adults: evaluation of a short form of the CES-D (Center for Epidemiologic Studies Depression Scale). Am J Prev Med. 1994;10(2):77–84.CrossRefPubMed Andresen EM, Malmgren JA, Carter WB, Patrick DL. Screening for depression in well older adults: evaluation of a short form of the CES-D (Center for Epidemiologic Studies Depression Scale). Am J Prev Med. 1994;10(2):77–84.CrossRefPubMed
7.
go back to reference Zhang Y, Ge M, Zhao W, Liu Y, Xia X, Hou L, et al. Sensory Impairment and All-Cause Mortality Among the Oldest-Old: Findings from the Chinese Longitudinal Healthy Longevity Survey (CLHLS). J Nutr Health Aging. 2020;24(2):132–7.CrossRefPubMed Zhang Y, Ge M, Zhao W, Liu Y, Xia X, Hou L, et al. Sensory Impairment and All-Cause Mortality Among the Oldest-Old: Findings from the Chinese Longitudinal Healthy Longevity Survey (CLHLS). J Nutr Health Aging. 2020;24(2):132–7.CrossRefPubMed
8.
go back to reference Zheng PP, Guo ZL, Du XJ, Yang HM, Wang ZJ. Prevalence of Disability among the Chinese Older Population: A Systematic Review and Meta-Analysis. Int J Environ Res Public Health. 2022;19(3):1656.CrossRefPubMedPubMedCentral Zheng PP, Guo ZL, Du XJ, Yang HM, Wang ZJ. Prevalence of Disability among the Chinese Older Population: A Systematic Review and Meta-Analysis. Int J Environ Res Public Health. 2022;19(3):1656.CrossRefPubMedPubMedCentral
9.
go back to reference Nguyen VC, Moon S, Oh E, Hong GS. Factors Associated With Functional Limitations in Daily Living Among Older Adults in Korea: A Cross-Sectional Study. Int J Public Health. 2022;67:1605155.CrossRefPubMedPubMedCentral Nguyen VC, Moon S, Oh E, Hong GS. Factors Associated With Functional Limitations in Daily Living Among Older Adults in Korea: A Cross-Sectional Study. Int J Public Health. 2022;67:1605155.CrossRefPubMedPubMedCentral
10.
go back to reference Ukawa S, Tamakoshi A, Tani Y, Sasaki Y, Saito J, Haseda M, et al. Leisure activities and instrumental activities of daily living: A 3-year cohort study from the Japan Gerontological Evaluation Study. Geriatr Gerontol Int. 2022;22(2):152–9.CrossRefPubMed Ukawa S, Tamakoshi A, Tani Y, Sasaki Y, Saito J, Haseda M, et al. Leisure activities and instrumental activities of daily living: A 3-year cohort study from the Japan Gerontological Evaluation Study. Geriatr Gerontol Int. 2022;22(2):152–9.CrossRefPubMed
11.
go back to reference Zacarias-Pons L, Vilalta-Franch J, Turro-Garriga O, Saez M, Garre-Olmo J. Multimorbidity patterns and their related characteristics in European older adults: A longitudinal perspective. Arch Gerontol Geriatr. 2021;95:104428.CrossRefPubMed Zacarias-Pons L, Vilalta-Franch J, Turro-Garriga O, Saez M, Garre-Olmo J. Multimorbidity patterns and their related characteristics in European older adults: A longitudinal perspective. Arch Gerontol Geriatr. 2021;95:104428.CrossRefPubMed
12.
go back to reference Forslund T, Carlsson AC, Ljunggren G, Arnlov J, Wachtler C. Patterns of multimorbidity and pharmacotherapy: a total population cross-sectional study. Fam Pract. 2021;38(2):132–40.CrossRefPubMed Forslund T, Carlsson AC, Ljunggren G, Arnlov J, Wachtler C. Patterns of multimorbidity and pharmacotherapy: a total population cross-sectional study. Fam Pract. 2021;38(2):132–40.CrossRefPubMed
13.
go back to reference Rajoo SS, Wee ZJ, Lee PSS, Wong FY, Lee ES. A Systematic Review of the Patterns of Associative Multimorbidity in Asia. Biomed Res Int. 2021;2021:6621785.CrossRefPubMedPubMedCentral Rajoo SS, Wee ZJ, Lee PSS, Wong FY, Lee ES. A Systematic Review of the Patterns of Associative Multimorbidity in Asia. Biomed Res Int. 2021;2021:6621785.CrossRefPubMedPubMedCentral
14.
go back to reference Song LJ, Yang L. The Trajectory of Health Expectancy among Elderly and Its Influencing Factors: An Empirical Study Based on CLHLS. J Population & Economics. 2020;3:57–74. Song LJ, Yang L. The Trajectory of Health Expectancy among Elderly and Its Influencing Factors: An Empirical Study Based on CLHLS. J Population & Economics. 2020;3:57–74.
15.
go back to reference Yan W, Lu Y, Zhang R, Chang F. Multimorbidity status of the elderly in China-research based on CHARLS data. Chinese Journal of Disease Control & Prevention. 2019;23(4):426–30. Yan W, Lu Y, Zhang R, Chang F. Multimorbidity status of the elderly in China-research based on CHARLS data. Chinese Journal of Disease Control & Prevention. 2019;23(4):426–30.
16.
go back to reference Hu RH, Hsiao FY, Chen LJ, Huang PT, Hsu WW. Increasing age- and gender-specific burden and complexity of multimorbidity in Taiwan, 2003–2013: a cross-sectional study based on nationwide claims data. BMJ Open. 2019;9(6):e028333.CrossRefPubMedPubMedCentral Hu RH, Hsiao FY, Chen LJ, Huang PT, Hsu WW. Increasing age- and gender-specific burden and complexity of multimorbidity in Taiwan, 2003–2013: a cross-sectional study based on nationwide claims data. BMJ Open. 2019;9(6):e028333.CrossRefPubMedPubMedCentral
17.
go back to reference Forman DE, Maurer MS, Boyd C, Brindis R, Salive ME, Horne FM, et al. Multimorbidity in Older Adults With Cardiovascular Disease. J Am Coll Cardiol. 2018;71(19):2149–61.CrossRefPubMedPubMedCentral Forman DE, Maurer MS, Boyd C, Brindis R, Salive ME, Horne FM, et al. Multimorbidity in Older Adults With Cardiovascular Disease. J Am Coll Cardiol. 2018;71(19):2149–61.CrossRefPubMedPubMedCentral
18.
go back to reference van den Akker M, Vaes B, Goderis G, Van Pottelbergh G, De Burghgraeve T, Henrard S. Trends in multimorbidity and polypharmacy in the Flemish-Belgian population between 2000 and 2015. PLoS ONE. 2019;14(2): e0212046.CrossRefPubMedPubMedCentral van den Akker M, Vaes B, Goderis G, Van Pottelbergh G, De Burghgraeve T, Henrard S. Trends in multimorbidity and polypharmacy in the Flemish-Belgian population between 2000 and 2015. PLoS ONE. 2019;14(2): e0212046.CrossRefPubMedPubMedCentral
20.
go back to reference Pietzner M, Stewart ID, Raffler J, Khaw KT, Michelotti GA, Kastenmuller G, et al. Plasma metabolites to profile pathways in noncommunicable disease multimorbidity. Nat Med. 2021;27(3):471–9.CrossRefPubMedPubMedCentral Pietzner M, Stewart ID, Raffler J, Khaw KT, Michelotti GA, Kastenmuller G, et al. Plasma metabolites to profile pathways in noncommunicable disease multimorbidity. Nat Med. 2021;27(3):471–9.CrossRefPubMedPubMedCentral
21.
go back to reference Global Cardiovascular Risk C, Magnussen C, Ojeda FM, Leong DP, Alegre-Diaz J, Amouyel P, et al. Global Effect of Modifiable Risk Factors on Cardiovascular Disease and Mortality. N Engl J Med. 2023;389(14):1273–85.CrossRef Global Cardiovascular Risk C, Magnussen C, Ojeda FM, Leong DP, Alegre-Diaz J, Amouyel P, et al. Global Effect of Modifiable Risk Factors on Cardiovascular Disease and Mortality. N Engl J Med. 2023;389(14):1273–85.CrossRef
22.
go back to reference Collaborators GBDCRF. The global burden of cancer attributable to risk factors, 2010–19: a systematic analysis for the Global Burden of Disease Study 2019. Lancet. 2022;400(10352):563–91.CrossRef Collaborators GBDCRF. The global burden of cancer attributable to risk factors, 2010–19: a systematic analysis for the Global Burden of Disease Study 2019. Lancet. 2022;400(10352):563–91.CrossRef
23.
go back to reference Abe T, Nofuji Y, Seino S, Murayama H, Yoshida Y, Tanigaki T, et al. Healthy lifestyle behaviors and transitions in frailty status among independent community-dwelling older adults: The Yabu cohort study. Maturitas. 2020;136:54–9.CrossRefPubMed Abe T, Nofuji Y, Seino S, Murayama H, Yoshida Y, Tanigaki T, et al. Healthy lifestyle behaviors and transitions in frailty status among independent community-dwelling older adults: The Yabu cohort study. Maturitas. 2020;136:54–9.CrossRefPubMed
24.
go back to reference Hotta R, Doi T, Shimada H, Makizako H, Yoshida D, Anan Y, et al. Cigarette smoking and cognitive health in elderly Japanese. Am J Health Behav. 2015;39(3):294–3003.CrossRefPubMed Hotta R, Doi T, Shimada H, Makizako H, Yoshida D, Anan Y, et al. Cigarette smoking and cognitive health in elderly Japanese. Am J Health Behav. 2015;39(3):294–3003.CrossRefPubMed
25.
go back to reference Huang Z, Sun S, Lee M, Maslov AY, Shi M, Waldman S, et al. Single-cell analysis of somatic mutations in human bronchial epithelial cells in relation to aging and smoking. Nat Genet. 2022;54(4):492–8.CrossRefPubMedPubMedCentral Huang Z, Sun S, Lee M, Maslov AY, Shi M, Waldman S, et al. Single-cell analysis of somatic mutations in human bronchial epithelial cells in relation to aging and smoking. Nat Genet. 2022;54(4):492–8.CrossRefPubMedPubMedCentral
26.
go back to reference Bayes-Marin I, Sanchez-Niubo A, Egea-Cortes L, Nguyen H, Prina M, Fernandez D, et al. Multimorbidity patterns in low-middle and high income regions: a multiregion latent class analysis using ATHLOS harmonised cohorts. BMJ Open. 2020;10(7):e034441.CrossRefPubMedPubMedCentral Bayes-Marin I, Sanchez-Niubo A, Egea-Cortes L, Nguyen H, Prina M, Fernandez D, et al. Multimorbidity patterns in low-middle and high income regions: a multiregion latent class analysis using ATHLOS harmonised cohorts. BMJ Open. 2020;10(7):e034441.CrossRefPubMedPubMedCentral
27.
go back to reference Khorrami Z, Rezapour M, Etemad K, Yarahmadi S, Khodakarim S, Mahdavi Hezaveh A, et al. The patterns of Non-communicable disease Multimorbidity in Iran: A Multilevel Analysis. Sci Rep. 2020;10(1):3034.CrossRefPubMedPubMedCentral Khorrami Z, Rezapour M, Etemad K, Yarahmadi S, Khodakarim S, Mahdavi Hezaveh A, et al. The patterns of Non-communicable disease Multimorbidity in Iran: A Multilevel Analysis. Sci Rep. 2020;10(1):3034.CrossRefPubMedPubMedCentral
28.
go back to reference Geda NR, Janzen B, Pahwa P. Chronic disease multimorbidity among the Canadian population: prevalence and associated lifestyle factors. Arch Public Health. 2021;79(1):60.CrossRefPubMedPubMedCentral Geda NR, Janzen B, Pahwa P. Chronic disease multimorbidity among the Canadian population: prevalence and associated lifestyle factors. Arch Public Health. 2021;79(1):60.CrossRefPubMedPubMedCentral
29.
go back to reference Kivimaki M, Strandberg T, Pentti J, Nyberg ST, Frank P, Jokela M, et al. Body-mass index and risk of obesity-related complex multimorbidity: an observational multicohort study. Lancet Diabetes Endocrinol. 2022;10(4):253–63.CrossRefPubMedPubMedCentral Kivimaki M, Strandberg T, Pentti J, Nyberg ST, Frank P, Jokela M, et al. Body-mass index and risk of obesity-related complex multimorbidity: an observational multicohort study. Lancet Diabetes Endocrinol. 2022;10(4):253–63.CrossRefPubMedPubMedCentral
30.
go back to reference Lee HA, Park H. Comorbidity network analysis related to obesity in middle-aged and older adults: findings from Korean population-based survey data. Epidemiol Health. 2021;43:e2021018. https://doi.org/10.4178/epih.e2021018 3.8 Q2 . Epub 2021 Mar 5. PMID: 33677857; PMCID: PMC8060529. Lee HA, Park H. Comorbidity network analysis related to obesity in middle-aged and older adults: findings from Korean population-based survey data. Epidemiol Health. 2021;43:e2021018. https://​doi.​org/​10.​4178/​epih.​e2021018 3.8 Q2 . Epub 2021 Mar 5. PMID: 33677857; PMCID: PMC8060529.
31.
go back to reference Hu Y, Zhou F, Kaminga AC, Yan S, Hu Z. Associations of depressive symptoms and chronic diseases with activities of daily living among middle-aged and older population in China: A population-based cohort study. Front Psychiatry. 2022;13:848255.CrossRefPubMedPubMedCentral Hu Y, Zhou F, Kaminga AC, Yan S, Hu Z. Associations of depressive symptoms and chronic diseases with activities of daily living among middle-aged and older population in China: A population-based cohort study. Front Psychiatry. 2022;13:848255.CrossRefPubMedPubMedCentral
32.
go back to reference Ansari S, Anand A, Hossain B. Multimorbidity and depression among older adults in India: Mediating role of functional and behavioural health. PLoS ONE. 2022;17(6):e0269646.CrossRefPubMedPubMedCentral Ansari S, Anand A, Hossain B. Multimorbidity and depression among older adults in India: Mediating role of functional and behavioural health. PLoS ONE. 2022;17(6):e0269646.CrossRefPubMedPubMedCentral
33.
go back to reference Liu J, Li L, Zhang Z, Xu H. Associations between physical health and depressive symptoms in Chinese older adults: Do neighborhood resources matter? SSM Popul Health. 2016;2:531–5.CrossRefPubMedPubMedCentral Liu J, Li L, Zhang Z, Xu H. Associations between physical health and depressive symptoms in Chinese older adults: Do neighborhood resources matter? SSM Popul Health. 2016;2:531–5.CrossRefPubMedPubMedCentral
34.
go back to reference Nagarkar A, Kulkarni S. Association between daily activities and fall in older adults: an analysis of longitudinal ageing study in India (2017–18). BMC Geriatr. 2022;22(1):203.CrossRefPubMedPubMedCentral Nagarkar A, Kulkarni S. Association between daily activities and fall in older adults: an analysis of longitudinal ageing study in India (2017–18). BMC Geriatr. 2022;22(1):203.CrossRefPubMedPubMedCentral
35.
go back to reference Muneera K, Muhammad T, Pai M, Ahmed W, Althaf S. Associations between intrinsic capacity, functional difficulty, and fall outcomes among older adults in India. Sci Rep. 2023;13(1):9829.CrossRefPubMedPubMedCentral Muneera K, Muhammad T, Pai M, Ahmed W, Althaf S. Associations between intrinsic capacity, functional difficulty, and fall outcomes among older adults in India. Sci Rep. 2023;13(1):9829.CrossRefPubMedPubMedCentral
Metadata
Title
Chronic disease and multimorbidity in the Chinese older adults’ population and their impact on daily living ability: a cross-sectional study of the Chinese Longitudinal Healthy Longevity Survey (CLHLS)
Authors
Ye Chen
Huixia Ji
Yang Shen
Dandan Liu
Publication date
01-12-2024
Publisher
BioMed Central
Published in
Archives of Public Health / Issue 1/2024
Electronic ISSN: 2049-3258
DOI
https://doi.org/10.1186/s13690-024-01243-2

Other articles of this Issue 1/2024

Archives of Public Health 1/2024 Go to the issue