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Published in: BMC Public Health 1/2022

Open Access 01-12-2022 | Cholera | Research

Determining factors associated with cholera disease in Ethiopia using Bayesian hierarchical modeling

Authors: Tsigereda Tilahun Letta, Denekew Bitew Belay, Endale Alemayehu Ali

Published in: BMC Public Health | Issue 1/2022

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Abstract

Background

Cholera is a diarrheal disease caused by infection of the intestine with the gram-negative bacteria Vibrio cholera. It is caused by the ingestion of food or water and infected all age groups. This study aimed at identifying risk factors associated with cholera disease in Ethiopia using the Bayesian hierarchical model.

Methods

The study was conducted in Ethiopia across regions and this study used secondary data obtained from the Ethiopian public health institute. Latent Gaussian models were used in this study; which is a group of models that contains most statistical models used in practice. The posterior marginal distribution of the Latent Gaussian models with different priors is determined by R-Integrated Nested Laplace Approximation.

Results

There were 2790 cholera patients in Ethiopia across the regions. There were 81.61% of patients are survived from cholera outbreak disease and the rest 18.39% have died. There was 39% variation across the region in Ethiopia. Latent Gaussian models including random and fixed effects with standard priors were the best model to fit the data based on deviance. The odds of surviving from cholera outbreak disease for inpatient status are 0.609 times less than the outpatient status.

Conclusions

The authors conclude that the fitted latent Gaussian models indicate the predictor variables; admission status, aged between 15 and 44, another sick person in a family, dehydration status, oral rehydration salt, intravenous, and antibiotics were significantly associated with cholera outbreak disease.
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Metadata
Title
Determining factors associated with cholera disease in Ethiopia using Bayesian hierarchical modeling
Authors
Tsigereda Tilahun Letta
Denekew Bitew Belay
Endale Alemayehu Ali
Publication date
01-12-2022
Publisher
BioMed Central
Keyword
Cholera
Published in
BMC Public Health / Issue 1/2022
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/s12889-022-14153-1

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