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01-06-2006 | Case Report

Cholelithiasis and Thrombosis of the Central Retinal Vein in a Renal Transplant Recipient Treated with Cyclosporin

Authors: Dr Petra Simic, Vladimir Gasparovic, Mate Skegro, Ranka Stern-Padovan

Published in: Clinical Drug Investigation | Issue 6/2006

Abstract

The use of cyclosporin has been associated with the development of cholelithiasis in transplant recipients. Cholelithiasis in turn enhances the effects of cyclosporin on increased platelet aggregation.

In this report, a patient who had undergone a renal transplantation as a result of malignant hypertension, and who was on immunosuppressive therapy consisting of cyclosporin, prednisone and azathioprine, developed thrombosis of the central retinal vein 5 years following the transplantation. Seven years after the transplantation, cholelithiasis, cholecystitis, cholangitis and subsequently secondary chronic biliary sclerosis were detected. Latero-lateral anastomosis between the common bile duct and duodenum was performed during explorative laparotomy and ursodeoxycholic acid treatment was introduced. The possible inter-relationship of the cholestatis, central retinal vein thrombosis and immunosuppression are discussed.

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Title: Cholelithiasis and Thrombosis of the Central Retinal Vein in a Renal Transplant Recipient Treated with Cyclosporin
Authors: Dr Petra Simic
Vladimir Gasparovic
Mate Skegro
Ranka Stern-Padovan
Publication date: 01-06-2006
Publisher: Springer International Publishing
Published in: Clinical Drug Investigation / Issue 6/2006
Print ISSN: 1173-2563
Electronic ISSN: 1179-1918
DOI: https://doi.org/10.2165/00044011-200626060-00008

Keynote webinar | Spotlight on medication adherence

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Cholelithiasis and Thrombosis of the Central Retinal Vein in a Renal Transplant Recipient Treated with Cyclosporin

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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