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Surgical Endoscopy

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Open Access 01-12-2021 | Cholecystectomy

The minimally important difference of the Gastrointestinal Quality of Life Index for symptomatic gallstone surgery

Authors: Jason M. Sutherland, Carmela Melina Albanese, Trafford Crump, Guiping Liu, Ahmer Karimuddin

Published in: Surgical Endoscopy | Issue 12/2021

Abstract

Introduction

The Gastrointestinal Quality of Life Index (GQLI) is used to measure domains of health and symptoms among people with gastrointestinal disorders. The objective of this study is to calculate the smallest change in the GQLI that is perceived by patients as meaningful among a sample of English-speaking adult patients undergoing elective laparoscopic cholecystectomy for treatment of symptomatic gallbladder disease.

Materials and methods

The study is based on retrospective analyses of a sample of participants completing the GQLI and the EQ-5D(3L) preoperatively and six months postoperatively in Vancouver, Canada. Patients are excluded if they are less than 19 years of age, cannot communicate in English, or reside in a long-term care facility. The MID is calculated for the GQLI’s domains using distribution and anchor-based methods.

Results

Among eligible patients, the participation rate was 51%. The estimated MID for the overall GQLI value ranged between 4.32 and 11.44. There were no statistically significant differences in the GQLI’s MID values between sexes or age subgroups. There were statistically significant differences in the GQLI’s MID values by baseline health status.

Discussion

This study should provide some comfort that the MID values used in discussing change in health and symptoms with elective cholecystectomy patients are robust to sex. Although the sample size may have been inadequate for age-based analyses, the study found large differences in MID values between age subgroups. Statistically significant differences in MID values based on preoperative health supports reporting MID values separately by baseline value. Further research should explore whether age-based differences in MID values exist using larger samples.

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Title: The minimally important difference of the Gastrointestinal Quality of Life Index for symptomatic gallstone surgery
Authors: Jason M. Sutherland
Carmela Melina Albanese
Trafford Crump
Guiping Liu
Ahmer Karimuddin
Publication date: 01-12-2021
Publisher: Springer US
Keyword: Cholecystectomy
Published in: Surgical Endoscopy / Issue 12/2021
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI: https://doi.org/10.1007/s00464-020-08205-z

Keynote webinar | Spotlight on medication adherence

Springer Medicine

The minimally important difference of the Gastrointestinal Quality of Life Index for symptomatic gallstone surgery

Abstract

Introduction

Materials and methods

Results

Discussion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Introduction

Materials and methods

Results

Discussion

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