Top

Published in:

01-03-2022 | Correspondence

Choice of priors: how much scepticism is appropriate?

Authors: Anders Granholm, Marie Warrer Munch, Morten Hylander Møller, Theis Lange, Anders Perner

Published in: Intensive Care Medicine | Issue 3/2022

Excerpt

We thank de Grooth and Elbers for their interest in our Bayesian analysis of the COVID STEROID 2 trial [1‐3] and their letter [4] discussing the sceptical priors used in the sensitivity analyses. …

Granholm A, Munch MW, Myatra SN et al (2021) Dexamethasone 12 mg versus 6 mg for patients with COVID-19 and severe hypoxaemia: a pre-planned, secondary Bayesian analysis of the COVID STEROID 2 trial. Intensive Care Med. https://doi.org/10.1007/s00134-021-06573-1CrossRefPubMedPubMedCentral

Granholm A, Munch MW, Myatra SN et al (2021) Higher vs lower doses of dexamethasone in patients with COVID-19 and severe hypoxia (COVID STEROID 2) trial: protocol for a secondary Bayesian analysis. Acta Anaesthesiol Scand 65:702–710CrossRef

COVID STEROID 2 Trial Group (2021) Effect of 12 mg vs 6 mg of dexamethasone on the number of days alive without life support in adults with COVID-19 and severe hypoxemia: the COVID STEROID 2 randomized trial. JAMA 326:1807–1817CrossRef

de Grooth H, Elbers P (2021) Pick your prior: scepticism about sceptical prior beliefs. Intensive Care Med. https://doi.org/10.1007/s00134-021-06602-zCrossRefPubMedPubMedCentral

Zampieri FG, Casey JD, Shankar-Hari M, Harrell FE Jr, Harhay MO (2021) Using Bayesian methods to augment the interpretation of critical care trials. an overview of theory and example reanalysis of the alveolar recruitment for acute respiratory distress syndrome trial. Am J Respir Crit Care Med 203:543–552CrossRef

Title: Choice of priors: how much scepticism is appropriate?
Authors: Anders Granholm
Marie Warrer Munch
Morten Hylander Møller
Theis Lange
Anders Perner
Publication date: 01-03-2022
Publisher: Springer Berlin Heidelberg
Published in: Intensive Care Medicine / Issue 3/2022
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-021-06613-w

At a glance: The STEP trials

Springer Medicine

Choice of priors: how much scepticism is appropriate?

Excerpt

At a glance: The STEP trials

Springer Medicine

Excerpt

Please log in to get access to this content

Other articles of this Issue 3/2022

Effect of therapeutic drug monitoring-based dose optimization of piperacillin/tazobactam on sepsis-related organ dysfunction in patients with sepsis: a randomized controlled trial

Veno-venous extracorporeal membrane oxygenation (vv-ECMO) for severe respiratory failure in adult cancer patients: a retrospective multicenter analysis

Effect of prone positioning on survival in adult patients receiving venovenous extracorporeal membrane oxygenation for acute respiratory distress syndrome: a systematic review and meta-analysis

Undocumented migrants in French intensive care units in 2011–2018: retrospective nationwide study

Correction to: Prognostic value of global deep white matter DTI metrics for 1-year outcome prediction in ICU traumatic brain injury patients: an MRI-COMA and CENTER-TBI combined study

Epinephrine versus norepinephrine in cardiac arrest patients with post-resuscitation shock