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Pediatric Surgery International
Published in: Pediatric Surgery International 7/2011

01-07-2011 | Original Article

Chinese pediatric and adolescent primary tracheobronchial tumors: a hospital-based study

Authors: Yongfeng Yu, Zhengbo Song, Zhiwei Chen, Hong Jian, Shun Lu

Published in: Pediatric Surgery International | Issue 7/2011

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Abstract

Objectives

To investigate the clinical characteristics and treatment outcomes in Chinese pediatric and adolescent patients with primary tracheobronchial tumors by focusing upon the exploration of prognostic factors.

Methods

A retrospective review of medical records collected from January 1996 through June 2009 was conducted within a single institution, inclusive of the total 19 treated pediatric and adolescent patients (3 benign tumors, 16 malignant tumors). A parallel comparison of adult cases with tracheobronchial tumor was performed to the pediatric and adolescent cases.

Results

The chart review of pediatric and adolescent case reports revealed 19 cases with primary tracheobronchial tumors. Final pathologic diagnosis included 14 (73.68%) mucoepidermoid carcinoma (ME), 2 (10.53%) carcinoid tumor, 2 (10.53%) papillomatosis and 1 (5.26%) neurofibroma. Median age upon diagnosis was 12 years (range 4–18 years). Chest imaging revealed common abnormal radiographic atelectasis (12/19). Patients with localized disease received surgical tumor resection. There were a total of 8 (42.1%) sleeve resections, 4 (21.1%) resection of anatomically related lung parenchyma (1 bilateral lobectomies, 2 lobectomies, 1 pneumonectomy) and 7 local tumor resections. No surgery-related deaths or complications were observed. 16 patients (84.2%) remained disease free with a median follow-up of 70.5 months (range 44–168 months).

Conclusions

Our hospital data indicated a high incidence of ME, presenting the difference in the incidence rates between Chinese and western populations. Sleeve lobectomy provides efficient treatment with excellent prognosis among Chinese pediatric and adolescent patients.
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Metadata
Title
Chinese pediatric and adolescent primary tracheobronchial tumors: a hospital-based study
Authors
Yongfeng Yu
Zhengbo Song
Zhiwei Chen
Hong Jian
Shun Lu
Publication date
01-07-2011
Publisher
Springer-Verlag
Published in
Pediatric Surgery International / Issue 7/2011
Print ISSN: 0179-0358
Electronic ISSN: 1437-9813
DOI
https://doi.org/10.1007/s00383-011-2858-8

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