Top

Published in:

01-02-2012 | Original Article

Childhood dysfunctional voiding is differentially associated with urinary incontinence subtypes in women

Authors: Vatche A. Minassian, Mehran H. Langroudi, Mitesh Parekh, Deborah Poplawsky, H. Lester Kirchner, Jennifer Sartorius

Published in: World Journal of Urology | Issue 1/2012

Abstract

Purpose

To estimate the relationship between the history of childhood dysfunctional voiding and urinary incontinence (UI) in adult women with and without clinical UI and to estimate its relationship with stress, urge, and mixed UI.

Materials and methods

Using a case–control study, we surveyed adult women with or without UI using a validated dysfunctional voiding questionnaire. Cases were clinically classified as stress, urge, or mixed UI. Patient characteristics were compared using Student’s t-test, chi-square test, and Fisher’s exact test. Confounders were controlled through logistic regression. We compared the history of childhood dysfunctional voiding status among the three UI subtypes using multinomial logistic regression.

Results

We recruited 267 cases (120 stress, 37 urge, 98 mixed, and 12 other UI) and 107 controls. Mean age of cases and controls were 58 and 52 years and BMI 26 and 23 kg/m², respectively. Fifty-six percent of cases (48% stress, 65% urge, and 62% mixed UI) had a prevalence of childhood dysfunctional voiding compared to controls (40%) (P = 0.06). After adjusting for confounders, women with adult UI had a twofold increased odds (95% CI = 1.2–3.4, P = 0.006) of childhood dysfunctional voiding compared with controls. The highest prevalence of dysfunctional voiding was with urge UI (OR = 4.4, 95% CI = 1.8–10.7) followed by mixed UI (OR = 2.7, 95% CI = 1.5–5.2), and finally stress UI (OR = 1.4, 95% CI = 0.8–2.5).

Conclusion

Childhood dysfunctional voiding may predict adult bladder control problems. This association is strongest in women with urge UI followed by mixed UI, but not different between women with stress UI and controls.

Fowler CJ, Griffiths D, de Groat WC (2008) The neural control of micturition. Nat Rev Neurosci 9:453–466PubMedCrossRef

Holmdahl G, Hanson E, Hanson M, Hellstrom AL, Hjalmas K, Sillen U (1996) Four-hour voiding observation in healthy infants. J Urol 156:1809–1812PubMedCrossRef

Norgaard JP, van Gool JD, Hjalmas K, Djurhuus JC, Hellstrom AL (1998) Standardization and definitions in lower urinary tract dysfunction in children. International children’s continence society. Br J Urol 81:1–16PubMed

Krantz I, Jylkas E, Ahlberg BM, Wedel H (1994) On the epidemiology of nocturnal enuresis–a critical review of methods used in descriptive epidemiological studies on nocturnal enuresis. Scand J Urol Nephrol Suppl 163:75–82PubMed

Swithinbank LV, Brookes ST, Shepherd AM, Abrams P (1998) The natural history of urinary symptoms during adolescence. Br J Urol 81:90–93PubMedCrossRef

Bloom DA, Seeley WW, Ritchey ML, McGuire EJ (1993) Toilet habits and continence in children: an opportunity sampling in search of normal parameters. J Urol 149:1087–1090PubMed

Hellstrom AL, Hanson E, Hansson S, Hjalmas K, Jodal U (1990) Micturition habits and incontinence in 7-year-old Swedish school entrants. Eur J Pediatr 149:434–437PubMedCrossRef

Moore KH, Richmond DH, Parys BT (1991) Sex distribution of adult idiopathic detrusor instability in relation to childhood bedwetting. Br J Urol 68:479–482PubMedCrossRef

Foldspang A, Mommsen S (1994) Adult female urinary incontinence and childhood bedwetting. J Urol 152:85–88PubMed

10.

Kuh D, Cardozo L, Hardy R (1999) Urinary incontinence in middle aged women: childhood enuresis and other lifetime risk factors in a British prospective cohort. J Epidemiol Community Health 53:453–458PubMedCrossRef

11.

Fitzgerald MP, Thom DH, Wassel-Fyr C, Subak L, Brubaker L, Van Den Eeden SK, Brown JS (2006) Childhood urinary symptoms predict adult overactive bladder symptoms. J Urol 175:989–993PubMedCrossRef

12.

Minassian VA, Lovatsis D, Pascali D, Alarab M, Drutz HP (2006) Effect of childhood dysfunctional voiding on urinary incontinence in adult women. Obstet Gynecol 107:1247–1251PubMedCrossRef

13.

Farhat W, Bagli DJ, Capolicchio G, O’Reilly S, Merguerian PA, Khoury A, McLorie GA (2000) The dysfunctional voiding scoring system: quantitative standardization of dysfunctional voiding symptoms in children. J Urol 164:1011–1015PubMedCrossRef

14.

Abrams P, Cardozo L, Fall M, Griffiths D, Rosier P, Ulmsten U, Van Kerrebroeck P, Victor A, Wein A (2002) The standardisation of terminology of lower urinary tract function: report from the standardisation sub-committee of the international continence society. Neurourol Urodyn 21:167–178PubMedCrossRef

15.

Duel BP, Steinberg-Epstein R, Hill M, Lerner M (2003) A survey of voiding dysfunction in children with attention deficit-hyperactivity disorder. J Urol 170:1521–1523PubMedCrossRef

16.

Upadhyay J, Bolduc S, Bagli DJ, McLorie GA, Khoury AE, Farhat W (2003) Use of the dysfunctional voiding symptom score to predict resolution of vesicoureteral reflux in children with voiding dysfunction. J Urol 169:5

17.

Elia G, Bergman J, Dye TD (2002) Familial incidence of urinary incontinence. Am J Obstet Gynecol 187:53–55PubMedCrossRef

18.

Buchsbaum GM, Duecy EE (2008) Incontinence and pelvic organ prolapse in parous/nulliparous pairs of identical twins. Neurourol Urodyn 27:496–498PubMedCrossRef

19.

Hannestad YS, Lie RT, Rortveit G, Hunskaar S (2004) Familial risk of urinary incontinence in women: population based cross sectional study. BMJ 329:889–891PubMedCrossRef

20.

Rohr G, Kragstrup J, Gaist D, Christensen K (2004) Genetic and environmental influences on urinary incontinence: a Danish population-based twin study of middle-aged and elderly women. Acta Obstet Gynecol Scand 83:978–982PubMed

21.

Cheung W, Bluth MJ, Johns C, Khan S, Lin YY, Bluth MH (2010) Peripheral blood mononuclear cell gene array profiles in patients with overactive bladder. Urology 75:896–901PubMedCrossRef

22.

Davila GW, Bernier F, Franco J, Kopka SL (2003) Bladder dysfunction in sexual abuse survivors. J Urol 170:476–479PubMedCrossRef

Title: Childhood dysfunctional voiding is differentially associated with urinary incontinence subtypes in women
Authors: Vatche A. Minassian
Mehran H. Langroudi
Mitesh Parekh
Deborah Poplawsky
H. Lester Kirchner
Jennifer Sartorius
Publication date: 01-02-2012
Publisher: Springer-Verlag
Published in: World Journal of Urology / Issue 1/2012
Print ISSN: 0724-4983
Electronic ISSN: 1433-8726
DOI: https://doi.org/10.1007/s00345-011-0665-4

2024 ASCO Annual Meeting

Springer Medicine

Childhood dysfunctional voiding is differentially associated with urinary incontinence subtypes in women

Abstract

Purpose

Materials and methods

Results

Conclusion

2024 ASCO Annual Meeting

Springer Medicine

Abstract

Purpose

Materials and methods

Results

Conclusion

Please log in to get access to this content

Other articles of this Issue 1/2012

Advances in non-surgical treatments for urinary tract infections in children

Urinary tract infection associated with conditions causing urinary tract obstruction and stasis, excluding urolithiasis and neuropathic bladder

Urologic complications of genitourinary schistosomiasis

Should we abstain from Gleason score 2–4 in the diagnosis of prostate cancer? Results of a German multicentre study

Prognostic relevance of number and bilaterality of positive surgical margins after radical prostatectomy

Editorial