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Open Access 01-06-2009 | Original Article

Child and parental adaptation to pediatric stem cell transplantation

Authors: C. M. Jantien Vrijmoet-Wiersma, Annemarie M. Kolk, Martha A. Grootenhuis, Emmelien M. Spek, Jeanine M. M. van Klink, R. Maarten Egeler, Robbert G. M. Bredius, Hendrik M. Koopman

Published in: Supportive Care in Cancer | Issue 6/2009

Abstract

Goals of work

Allogeneic pediatric stem cell transplantation (SCT) is a very intensive treatment with a high mortality and morbidity. The objectives of this study were to assess the (1) self- and proxy-reported health-related quality of life (HRQoL) compared to a norm group, (2) levels of parenting stress compared to a norm group, (3) differences in HRQoL and parenting stress pre- and post-SCT, and (4) effect of child age and parenting stress on self- and proxy-reported HRQoL pre- and post-SCT.

Materials and methods

Pre- and on average 10 months post-SCT, 21 children and adolescents and their parent(s) completed questionnaires on HRQoL and the mothers completed a measure of parenting stress.

Main results

Post-SCT, home functioning, physical functioning, and total HRQoL scores were lower than the norm group. We found stable HRQoL scores over time with the exception of the domain home functioning, which was rated lower post-SCT than pre-SCT. Parents reported lower HRQoL scores than the children pre- and post-SCT and younger children experienced better HRQoL than older children. Parenting stress was higher post-SCT than pre-SCT and high levels of parenting stress were predictive of poor parental ratings of child HRQoL post-SCT.

Conclusions

Ongoing psychosocial assessment post-SCT is necessary to target children with a lowered HRQoL and parents who experience elevated parenting stress who may be in greater need of more supportive care.

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Title: Child and parental adaptation to pediatric stem cell transplantation
Authors: C. M. Jantien Vrijmoet-Wiersma
Annemarie M. Kolk
Martha A. Grootenhuis
Emmelien M. Spek
Jeanine M. M. van Klink
R. Maarten Egeler
Robbert G. M. Bredius
Hendrik M. Koopman
Publication date: 01-06-2009
Publisher: Springer-Verlag
Published in: Supportive Care in Cancer / Issue 6/2009
Print ISSN: 0941-4355
Electronic ISSN: 1433-7339
DOI: https://doi.org/10.1007/s00520-008-0544-8

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