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Published in: Insights into Imaging 4/2015

Open Access 01-08-2015 | Pictorial Review

Chemotherapy-related complications in the kidneys and collecting system: an imaging perspective

Authors: Jemianne Bautista Jia, Chandana Lall, Temel Tirkes, Rajesh Gulati, Ramit Lamba, Scott C. Goodwin

Published in: Insights into Imaging | Issue 4/2015

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Abstract

Nephrotoxicity is a common adverse effect of many chemotherapeutic agents. The agents most commonly associated with chemotherapy-associated nephrotoxicity are methotrexate, semustine, streptozocin, mithramycin, and cisplatin. Certain chemotherapeutic agents have adverse effects on the kidneys and urothelium that can be visualized radiographically, including cystic change, interstitial nephritis, papillary necrosis, urothelial changes, haemorrhagic cystitis, acute tubular necrosis, and infarction. This review focuses on imaging features identifying complications of chemotherapy in the kidneys and collecting system and provides didactic cases to alert referring clinicians.

Teaching Points

Nephrotoxicity is a common adverse effect of many chemotherapeutic agents.
Chemotherapies have adverse renal and urothelial effects that can be visualized radiographically.
Crizotinib use can result in the development of complex renal cysts.
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Metadata
Title
Chemotherapy-related complications in the kidneys and collecting system: an imaging perspective
Authors
Jemianne Bautista Jia
Chandana Lall
Temel Tirkes
Rajesh Gulati
Ramit Lamba
Scott C. Goodwin
Publication date
01-08-2015
Publisher
Springer Berlin Heidelberg
Published in
Insights into Imaging / Issue 4/2015
Electronic ISSN: 1869-4101
DOI
https://doi.org/10.1007/s13244-015-0417-x

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