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Journal of Medical Case Reports

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Open Access 01-12-2015 | Case report

Chemotherapeutic treatment of colorectal cancer in pregnancy: case report

Authors: Ziyad Makoshi, Claire Perrott, Khadija Al-Khatani, Fadia Al-Mohaisen

Published in: Journal of Medical Case Reports | Issue 1/2015

Abstract

Introduction

Colon cancer in pregnancy is uncommon. Only a small number of case reports have been published in the literature on the use of chemotherapeutic drugs during pregnancy. Reports of such cases assist clinicians in further investigating the use of chemotherapy in pregnancy.

Case presentation

FOLFOX-6 was administered to a pregnant, 33-year-old Saudi woman with metastatic colon cancer from 22 to 30 weeks of gestation. Her cancer was diagnosed during her pregnancy. She tolerated the chemotherapy well and delivered a full-term baby girl with no obvious harm, and normal development was documented at her 2-year follow-up examination.

Conclusion

Colon cancer during pregnancy is not easily detected and is difficult to manage. A detailed history and high clinical suspicion are needed in patients who present with symptoms and signs suggestive of malignancy. A multidisciplinary approach with patient involvement is needed to decrease morbidity and mortality caused by both treatment and the cancer in the mother and to limit side effects for the fetus. Further data and long-term follow-up are needed to better understand the potential long-term side effects of chemotherapeutic drugs on offspring.

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Title: Chemotherapeutic treatment of colorectal cancer in pregnancy: case report
Authors: Ziyad Makoshi
Claire Perrott
Khadija Al-Khatani
Fadia Al-Mohaisen
Publication date: 01-12-2015
Publisher: BioMed Central
Published in: Journal of Medical Case Reports / Issue 1/2015
Electronic ISSN: 1752-1947
DOI: https://doi.org/10.1186/s13256-015-0621-9

At a glance: The STEP trials

Springer Medicine

Chemotherapeutic treatment of colorectal cancer in pregnancy: case report

Abstract

Introduction

Case presentation

Conclusion

At a glance: The STEP trials

Springer Medicine

Abstract

Introduction

Case presentation

Conclusion

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