Skip to main content
Top
Published in: Journal of Occupational Medicine and Toxicology 1/2020

Open Access 01-12-2020 | Research

Chemical risk and safety awareness, perception, and practices among research laboratories workers in Italy

Authors: Rosa Papadopoli, Carmelo Giuseppe Angelo Nobile, Alessandro Trovato, Claudia Pileggi, Maria Pavia

Published in: Journal of Occupational Medicine and Toxicology | Issue 1/2020

Login to get access

Abstract

Introduction

Exposure to chemical compounds occurs in numerous occupational settings, among which the research and healthcare laboratories have not been adequately investigated. These settings are characterized by an extreme variability of the used compounds and by the frequent turnover of young researchers. The main objectives of the study were to explore the occupational exposure to hazardous chemical substances among research laboratory workers; to assess their awareness and perceptions regarding chemical hazards; to investigate adherence to guidelines on safe handling of chemical compounds; and to analyze the effects of several factors on these outcomes of interest.

Methods

The survey was conducted among research laboratories workers who were exposed to chemical substances during their activity. Subjects completed a questionnaire exploring knowledge, attitudes and behaviors related to chemical hazards involved in research activities.

Results

Enrolled subjects were 237, for an 81.7% response rate. More than 90 hazardous chemical substances were used in the surveyed laboratories. A correct knowledge on hazardous chemicals was significantly more likely in younger researchers, in those manipulating a higher number of hazardous chemicals, and in those with a higher number of years of training in the attended laboratory; 54.4% of the workers said they felt very exposed to chemical risk. Correct practices in the laboratories were significantly more likely in researchers who perceived to have a low exposure to chemicals, but a high exposure to biological risk, who agreed with the statement that colleagues handle chemicals following safety procedures and who perceived to have received an adequate training in the management of accidents and first aid.

Conclusions

Our results showed significant gaps in knowledge and scarce preparedness in the adherence to safety processes to prevent and contain risks related to use of chemical compounds in research laboratories.
Appendix
Available only for authorised users
Literature
2.
go back to reference Regulation (EC) No 1907/2006 of the European Parliament and of the Council of 18 December 2006 concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH), establishing a European Chemicals Agency, amending Directive 1999/45/EC and repealing Council Regulation (EEC) No 793/93 and Commission Regulation (EC) No 1488/94 as well as Council Directive 76/769/EEC and Commission Directives 91/155/EEC, 93/67/EEC, 93/105/EC and 2000/21/EC Available at : https://eur-lex.europa.eu/legal-content/EN/ALL/?uri=CELEX%3A32006R1907. Accessed 5 Feb 2020. Regulation (EC) No 1907/2006 of the European Parliament and of the Council of 18 December 2006 concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH), establishing a European Chemicals Agency, amending Directive 1999/45/EC and repealing Council Regulation (EEC) No 793/93 and Commission Regulation (EC) No 1488/94 as well as Council Directive 76/769/EEC and Commission Directives 91/155/EEC, 93/67/EEC, 93/105/EC and 2000/21/EC Available at : https://​eur-lex.​europa.​eu/​legal-content/​EN/​ALL/​?​uri=​CELEX%3A32006R1907. Accessed 5 Feb 2020.
3.
go back to reference Regulation (EC) No 1272/2008 - classification, labelling and packaging of substances and mixtures (CLP) of the European Parliament and of the Council of 16 December 2008 on classification, labelling and packaging of substances and mixtures, amending and repealing Directives 67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006. Available at: https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX%3A32008R1272. Accessed 5 Feb 2020. Regulation (EC) No 1272/2008 - classification, labelling and packaging of substances and mixtures (CLP) of the European Parliament and of the Council of 16 December 2008 on classification, labelling and packaging of substances and mixtures, amending and repealing Directives 67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006. Available at: https://​eur-lex.​europa.​eu/​legal-content/​EN/​TXT/​?​uri=​CELEX%3A32008R1272. Accessed 5 Feb 2020.
5.
go back to reference Krstev S, Perunicic B, Vidakovic A. Work practice and some adverse health effects in nurses handling antineoplastic drugs. Med Lav. 2003;94:432–9.PubMed Krstev S, Perunicic B, Vidakovic A. Work practice and some adverse health effects in nurses handling antineoplastic drugs. Med Lav. 2003;94:432–9.PubMed
6.
go back to reference Lawson CC, Rocheleau CM, Whelan EA, Lividoti Hibert EN, Grajewski B, Spiegelman D, et al. Occupational exposures among nurses and risk of spontaneous abortion. Am J Obstet Gynecol. 2012;206:327 e1–8.CrossRef Lawson CC, Rocheleau CM, Whelan EA, Lividoti Hibert EN, Grajewski B, Spiegelman D, et al. Occupational exposures among nurses and risk of spontaneous abortion. Am J Obstet Gynecol. 2012;206:327 e1–8.CrossRef
7.
go back to reference Fransman W, Kager H, Meijster T, Heederik D, Kromhout H, Portengen L, et al. Leukemia from dermal exposure to cyclophosphamide among nurses in the Netherlands: quantitative assessment of the risk. Ann Occup Hyg. 2014;58:271–82.PubMed Fransman W, Kager H, Meijster T, Heederik D, Kromhout H, Portengen L, et al. Leukemia from dermal exposure to cyclophosphamide among nurses in the Netherlands: quantitative assessment of the risk. Ann Occup Hyg. 2014;58:271–82.PubMed
8.
go back to reference Videnros C, Selander J, Wiebert P, Albin M, Plato N, Borgquist S, et al. Investigating the risk of breast cancer among women exposed to chemicals: a nested case-control study using improved exposure estimates. Int Arch Occup Environ Health. 2020;93:261–9.CrossRef Videnros C, Selander J, Wiebert P, Albin M, Plato N, Borgquist S, et al. Investigating the risk of breast cancer among women exposed to chemicals: a nested case-control study using improved exposure estimates. Int Arch Occup Environ Health. 2020;93:261–9.CrossRef
9.
go back to reference Pennisi M, Malaguarnera G, Puglisi V, Vinciguerra L, Vacante M, Malaguarnera M. Neurotoxicity of acrylamide in exposed workers. Int J Environ Res Public Health. 2013;10:3843–54.CrossRef Pennisi M, Malaguarnera G, Puglisi V, Vinciguerra L, Vacante M, Malaguarnera M. Neurotoxicity of acrylamide in exposed workers. Int J Environ Res Public Health. 2013;10:3843–54.CrossRef
10.
go back to reference Driscoll TR, Carey RN, Peters S, Glass DC, Benke G, Reid A, et al. The Australian work exposures study: prevalence of occupational exposure to formaldehyde. Ann Occup Hyg. 2016;60:132–8.PubMed Driscoll TR, Carey RN, Peters S, Glass DC, Benke G, Reid A, et al. The Australian work exposures study: prevalence of occupational exposure to formaldehyde. Ann Occup Hyg. 2016;60:132–8.PubMed
11.
go back to reference Damalas C, Abdollahzadeh G. Farmers’ use of personal protective equipment during handling of plant protection products: determinants of implementation. Sci Total Environ. 2016;571:730–6.CrossRef Damalas C, Abdollahzadeh G. Farmers’ use of personal protective equipment during handling of plant protection products: determinants of implementation. Sci Total Environ. 2016;571:730–6.CrossRef
12.
go back to reference Ríos-González A, Jansen K, Sánchez-Pérez HJ. Pesticide risk perceptions and the differences between farmers and extensionists: towards a knowledge-in-context model. Environ Res. 2013;124:43–53.CrossRef Ríos-González A, Jansen K, Sánchez-Pérez HJ. Pesticide risk perceptions and the differences between farmers and extensionists: towards a knowledge-in-context model. Environ Res. 2013;124:43–53.CrossRef
13.
go back to reference Papadopoli R, Bianco A, Pepe D, Pileggi C, Pavia M. Sharps and needle-stick injuries among medical residents and healthcare professional students: pattern and reporting in Italy-a cross-sectional analytical study. Occup Environ Med. 2019;76:739–45.CrossRef Papadopoli R, Bianco A, Pepe D, Pileggi C, Pavia M. Sharps and needle-stick injuries among medical residents and healthcare professional students: pattern and reporting in Italy-a cross-sectional analytical study. Occup Environ Med. 2019;76:739–45.CrossRef
14.
go back to reference Wicker S, Jung J, Allwinn R, Gottschalk R, Rabenau HF. Prevalence and prevention of needlestick injuries among health care workers in a German university hospital. Int Arch Occup Environ Health. 2008;81:347–54.CrossRef Wicker S, Jung J, Allwinn R, Gottschalk R, Rabenau HF. Prevalence and prevention of needlestick injuries among health care workers in a German university hospital. Int Arch Occup Environ Health. 2008;81:347–54.CrossRef
15.
go back to reference Thomas WJ, Murray JR. The incidence and reporting rates of needle-stick injury amongst UK surgeons. Ann R Coll Surg Engl. 2009;91:12–7.CrossRef Thomas WJ, Murray JR. The incidence and reporting rates of needle-stick injury amongst UK surgeons. Ann R Coll Surg Engl. 2009;91:12–7.CrossRef
16.
go back to reference Byun HJ, Park JI. A review on chemical exposure and related health risks in laboratory workers. Korean J Environ Health Sci. 2010;36:441–55.CrossRef Byun HJ, Park JI. A review on chemical exposure and related health risks in laboratory workers. Korean J Environ Health Sci. 2010;36:441–55.CrossRef
17.
go back to reference Geer LA, Curbow BA, Anna DH, Lees PS, Buckley TJ. Development of a questionnaire to assess worker knowledge, attitudes and perceptions underlying dermal exposure. Scand J Work Environ Health. 2006;32:209–18.CrossRef Geer LA, Curbow BA, Anna DH, Lees PS, Buckley TJ. Development of a questionnaire to assess worker knowledge, attitudes and perceptions underlying dermal exposure. Scand J Work Environ Health. 2006;32:209–18.CrossRef
18.
go back to reference Connor TH, McDiarmid MA. Preventing occupational exposures to antineoplastic drugs in health care settings. CA Cancer J Clin. 2006;56:354–65.CrossRef Connor TH, McDiarmid MA. Preventing occupational exposures to antineoplastic drugs in health care settings. CA Cancer J Clin. 2006;56:354–65.CrossRef
19.
go back to reference Kyprianou M, Kapsou M, Raftopoulos V, Soteriades ES. Knowledge, attitudes and beliefs of Cypriot nurses on the handling of antineoplastic agents. Eur J Oncol Nurs. 2010;14:278–82.CrossRef Kyprianou M, Kapsou M, Raftopoulos V, Soteriades ES. Knowledge, attitudes and beliefs of Cypriot nurses on the handling of antineoplastic agents. Eur J Oncol Nurs. 2010;14:278–82.CrossRef
20.
go back to reference Hon CY, Teschke K, Shen H. Health care workers' knowledge, perceptions, and behaviors regarding antineoplastic drugs: survey from British Columbia, Canada. J Occup Environ Hyg. 2015;12:669–77.CrossRef Hon CY, Teschke K, Shen H. Health care workers' knowledge, perceptions, and behaviors regarding antineoplastic drugs: survey from British Columbia, Canada. J Occup Environ Hyg. 2015;12:669–77.CrossRef
21.
go back to reference Hosmer DW, Lemeshow S. Applied logistic regression. 2nd ed. New York: Wiley; 2000.CrossRef Hosmer DW, Lemeshow S. Applied logistic regression. 2nd ed. New York: Wiley; 2000.CrossRef
23.
go back to reference Schröder I, Huang DYQ, Ellis O, Gibson JH, Wayne NL. Laboratory safety attitudes and practices: a comparison of academic, government, and industry researchers. J Chem Health Saf. 2015;23:12–23.CrossRef Schröder I, Huang DYQ, Ellis O, Gibson JH, Wayne NL. Laboratory safety attitudes and practices: a comparison of academic, government, and industry researchers. J Chem Health Saf. 2015;23:12–23.CrossRef
24.
go back to reference Weinstein ND. Testing four competing theories of health-protective behavior. Health Psychol. 1993;12:324–33.CrossRef Weinstein ND. Testing four competing theories of health-protective behavior. Health Psychol. 1993;12:324–33.CrossRef
25.
go back to reference Rogers RW. A protection motivation theory of fear appeals and attitude change. J Psychol. 1975;91:93–114.CrossRef Rogers RW. A protection motivation theory of fear appeals and attitude change. J Psychol. 1975;91:93–114.CrossRef
26.
go back to reference Taylor WD, Snyder LA. The influence of risk perception on safety: a laboratory study. Saf Sci. 2017;95:116–24.CrossRef Taylor WD, Snyder LA. The influence of risk perception on safety: a laboratory study. Saf Sci. 2017;95:116–24.CrossRef
27.
go back to reference Nicotera G, Nobile CG, Bianco A, Pavia M. Environmental history-taking in clinical practice: knowledge, attitudes, and practice of primary care physicians in Italy. J Occup Environ Med. 2006;48:294–302.CrossRef Nicotera G, Nobile CG, Bianco A, Pavia M. Environmental history-taking in clinical practice: knowledge, attitudes, and practice of primary care physicians in Italy. J Occup Environ Med. 2006;48:294–302.CrossRef
Metadata
Title
Chemical risk and safety awareness, perception, and practices among research laboratories workers in Italy
Authors
Rosa Papadopoli
Carmelo Giuseppe Angelo Nobile
Alessandro Trovato
Claudia Pileggi
Maria Pavia
Publication date
01-12-2020
Publisher
BioMed Central
Published in
Journal of Occupational Medicine and Toxicology / Issue 1/2020
Electronic ISSN: 1745-6673
DOI
https://doi.org/10.1186/s12995-020-00268-x

Other articles of this Issue 1/2020

Journal of Occupational Medicine and Toxicology 1/2020 Go to the issue