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Published in: European Journal of Epidemiology 2/2010

01-02-2010 | COMMENTARY

Changing defaults in biobank research could save lives too

Authors: Joanna Stjernschantz Forsberg, Stefan Eriksson, Mats G. Hansson

Published in: European Journal of Epidemiology | Issue 2/2010

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Abstract

In an effort to increase the amount of organs available for transplantation, many countries have implemented presumed consent for organ donation. Presuming a wish to contribute to medical advances through biobank research on previously taken tissue samples could similarly improve health and wellbeing. In this article we analyze common arguments for and against presumed consent for organ donation and assess their relevance in the context of biobank research. In spite of obvious differences between biobank research and organ transplantation the cases for implementing presumption of a positive attitude appear quite analogous. It has repeatedly been shown that a majority of the general population supports these projects and selecting informed consent as the default position decreases the amount of organs and samples available and thus reduces the prospect of promoting health. We conclude that instead of presuming that individuals do not wish to contribute to the advancement of healthcare through biobank research on previously taken samples, ethics committees should presume that they do.
Literature
3.
go back to reference Abadie A, Gay S. The impact of presumed consent legislation on cadaveric organ donation: a cross-country study. J Health Econ. 2006;25:599–620.CrossRefPubMed Abadie A, Gay S. The impact of presumed consent legislation on cadaveric organ donation: a cross-country study. J Health Econ. 2006;25:599–620.CrossRefPubMed
4.
go back to reference Mossialos E, Costa-Font J, Rudisill C. Does organ donation legislation affect individuals’ willingness to donate their own or their relative’s organs? Evidence from European Union survey data. BMC Health Serv Res. 2008;8:48.CrossRefPubMed Mossialos E, Costa-Font J, Rudisill C. Does organ donation legislation affect individuals’ willingness to donate their own or their relative’s organs? Evidence from European Union survey data. BMC Health Serv Res. 2008;8:48.CrossRefPubMed
5.
go back to reference McCunn M, Mauritz W, Dutton RP, Alexander C, Handley C, Scalea TM. Impact of culture and policy on organ donation: a comparison between two urban trauma centers in developed nations. J Trauma. 2003;54:995–9.CrossRefPubMed McCunn M, Mauritz W, Dutton RP, Alexander C, Handley C, Scalea TM. Impact of culture and policy on organ donation: a comparison between two urban trauma centers in developed nations. J Trauma. 2003;54:995–9.CrossRefPubMed
6.
go back to reference Low HC, Da Costa M, Prabhakaran K, et al. Impact of new legislation on presumed consent on organ donation on liver transplant in Singapore: a preliminary analysis. Transplantation. 2006;82:1234–7.CrossRefPubMed Low HC, Da Costa M, Prabhakaran K, et al. Impact of new legislation on presumed consent on organ donation on liver transplant in Singapore: a preliminary analysis. Transplantation. 2006;82:1234–7.CrossRefPubMed
7.
go back to reference Jousilahti P, Salomaa V, Kuulasmaa K, Niemelä M, Vartiainen E. Total and cause specific mortality among participants and non-participants of population-based health surveys: a comprehensive follow-up of 54,372 Finnish men and women. J Epidemiol Community Health. 2005;59:310–5.CrossRefPubMed Jousilahti P, Salomaa V, Kuulasmaa K, Niemelä M, Vartiainen E. Total and cause specific mortality among participants and non-participants of population-based health surveys: a comprehensive follow-up of 54,372 Finnish men and women. J Epidemiol Community Health. 2005;59:310–5.CrossRefPubMed
8.
go back to reference Buckley B, Murphy AW, Byrne M, Glynn L. Selection bias resulting from the requirement for prior consent in observational research: a community cohort of people with ischaemic heart disease. Heart. 2007;93:1116–20.CrossRefPubMed Buckley B, Murphy AW, Byrne M, Glynn L. Selection bias resulting from the requirement for prior consent in observational research: a community cohort of people with ischaemic heart disease. Heart. 2007;93:1116–20.CrossRefPubMed
9.
go back to reference Helgesson G, Dillner J, Carlson J, Bartram CR, Hansson MG. Ethical framework for previously collected biobank samples. Nature Biotechnol. 2007;25:973–6.CrossRef Helgesson G, Dillner J, Carlson J, Bartram CR, Hansson MG. Ethical framework for previously collected biobank samples. Nature Biotechnol. 2007;25:973–6.CrossRef
10.
go back to reference Kaijser M. Examples from Swedish biobank research. In: Hansson MG, Levin M, editors. Biobanks as resources for health. Uppsala, Sweden: Universitetstryckeriet; 2003. p. 33–48. Kaijser M. Examples from Swedish biobank research. In: Hansson MG, Levin M, editors. Biobanks as resources for health. Uppsala, Sweden: Universitetstryckeriet; 2003. p. 33–48.
11.
go back to reference Jacob M. Another look at the presumed-versus-informed consent dichotomy in postmortem organ procurement. Bioethics. 2006;20:293–300.CrossRef Jacob M. Another look at the presumed-versus-informed consent dichotomy in postmortem organ procurement. Bioethics. 2006;20:293–300.CrossRef
13.
go back to reference Sanner MA. Two perspectives on organ donation: experiences of potential donor families and intensive care physicians of the same event. J Crit Care. 2007;22:296–304.CrossRefPubMed Sanner MA. Two perspectives on organ donation: experiences of potential donor families and intensive care physicians of the same event. J Crit Care. 2007;22:296–304.CrossRefPubMed
14.
go back to reference Kettis-Lindblad Å, Ring L, Viberth E, Hansson MG. Perceptions of potential donors in the Swedish public towards information and consent procedures in relation to use of human tissue samples in biobanks: a population-based study. Scand J Public Health. 2007;35:148–56.CrossRefPubMed Kettis-Lindblad Å, Ring L, Viberth E, Hansson MG. Perceptions of potential donors in the Swedish public towards information and consent procedures in relation to use of human tissue samples in biobanks: a population-based study. Scand J Public Health. 2007;35:148–56.CrossRefPubMed
15.
go back to reference Johnsson L, Hansson MG, Eriksson S, Helgesson G. Patients’ refusal to consent to storage and use of samples in Swedish biobanks: a cross-sectional study. BMJ. 2008;337:a345.CrossRefPubMed Johnsson L, Hansson MG, Eriksson S, Helgesson G. Patients’ refusal to consent to storage and use of samples in Swedish biobanks: a cross-sectional study. BMJ. 2008;337:a345.CrossRefPubMed
16.
go back to reference Hoeyer K, Olofsson B, Mjörndal T, Lynöe N. Informed consent and biobanks: a population-based study of attitudes toward tissue donation for genetic research. Scand J Public Health. 2004;32:224–9.CrossRefPubMed Hoeyer K, Olofsson B, Mjörndal T, Lynöe N. Informed consent and biobanks: a population-based study of attitudes toward tissue donation for genetic research. Scand J Public Health. 2004;32:224–9.CrossRefPubMed
17.
19.
20.
go back to reference English V, Sommerville A. Presumed consent for transplantation: a dead issue after Alder Hey? J Med Ethics. 2003;29:147–52.CrossRefPubMed English V, Sommerville A. Presumed consent for transplantation: a dead issue after Alder Hey? J Med Ethics. 2003;29:147–52.CrossRefPubMed
21.
23.
go back to reference Gundle K. Presumed consent: an international comparison and possibilities for change in the United States. Camb Q Healthc Ethics. 2005;14:113–8.CrossRefPubMed Gundle K. Presumed consent: an international comparison and possibilities for change in the United States. Camb Q Healthc Ethics. 2005;14:113–8.CrossRefPubMed
Metadata
Title
Changing defaults in biobank research could save lives too
Authors
Joanna Stjernschantz Forsberg
Stefan Eriksson
Mats G. Hansson
Publication date
01-02-2010
Publisher
Springer Netherlands
Published in
European Journal of Epidemiology / Issue 2/2010
Print ISSN: 0393-2990
Electronic ISSN: 1573-7284
DOI
https://doi.org/10.1007/s10654-009-9413-0

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