Skip to main content
Top
Published in: BMC Musculoskeletal Disorders 1/2021

Open Access 01-12-2021 | Research article

Cervical sagittal alignment after Prestige LP cervical disc replacement: radiological results and clinical impacts from a single-center experience

Authors: Xiaofei Wang, Yang Meng, Hao Liu, Hua Chen, Beiyu Wang, Ying Hong

Published in: BMC Musculoskeletal Disorders | Issue 1/2021

Login to get access

Abstract

Background

Cervical disc replacement (CDR) has been widely used to treat one- and two-level cervical degenerative disc disease. Studies have shown the effectiveness of CDR in preserving range of motion (ROM) and delaying adjacent segment degeneration (ASD). Cervical sagittal alignment is an important factor affecting favorable clinical outcomes in cervical spine surgery. This study aimed to explore whether cervical sagittal alignment can be maintained after CDR and to identify the impact of cervical sagittal alignment on outcomes after CDR.

Methods

This was a single-center, retrospective study. 132 patients who underwent one-level CDR were included. Cervical sagittal alignments, including cervical lordosis (CL), segmental alignment (SA), sagittal vertical axis (SVA), T1 slope (T1s), and T1s minus CL (T1s-CL), were measured. The effects of cervical sagittal alignment on the CDR outcomes were analyzed. Patients were divided into the heterotopic ossification (HO) group and ASD group to determine the potential impacts of cervical sagittal parameters.

Results

The cervical sagittal alignment parameters, except for the SVA, were significantly improved after CDR and showed decreasing trends at the last follow-up. Significantly higher CL and T1s were found in patients with better ROM after CDR. SVA ≥ 20 mm increased the risk of anterior HO (odds ratio = 2.945, P = 0.007). Significantly kyphotic SA and lower T1s values were found in the ASD patients than in the non-ASD patients (P < 0.05). Patients with ASD at the inferior level showed significantly worse CL (P < 0.05).

Conclusion

CDR had limited function of improving cervical sagittal alignment. Poor cervical sagittal alignment after CDR was associated with HO, ASD, and less ROM.
Appendix
Available only for authorised users
Literature
1.
go back to reference Scheer JK, Tang JA, Smith JS, Acosta FL, Protopsaltis TS, Blondel B, et al. Cervical spine alignment, sagittal deformity, and clinical implications: a review. J Neurosurg Spine. 2013;19:141–59.CrossRef Scheer JK, Tang JA, Smith JS, Acosta FL, Protopsaltis TS, Blondel B, et al. Cervical spine alignment, sagittal deformity, and clinical implications: a review. J Neurosurg Spine. 2013;19:141–59.CrossRef
2.
go back to reference Ferch RD, Shad A, Cadoux-Hudson TAD, Teddy PJ. Anterior correction of cervical kyphotic deformity: effects on myelopathy, neck pain, and sagittal alignment. J Neurosurg. 2004;100(1 Suppl Spine):13–9.PubMed Ferch RD, Shad A, Cadoux-Hudson TAD, Teddy PJ. Anterior correction of cervical kyphotic deformity: effects on myelopathy, neck pain, and sagittal alignment. J Neurosurg. 2004;100(1 Suppl Spine):13–9.PubMed
3.
go back to reference Hyun S-J, Kim K-J, Jahng T-A, Kim H-J. Clinical Impact of T1 Slope Minus Cervical Lordosis After Multilevel Posterior Cervical Fusion Surgery. Spine (Phila Pa 1976). 2017;42:1859–64.CrossRef Hyun S-J, Kim K-J, Jahng T-A, Kim H-J. Clinical Impact of T1 Slope Minus Cervical Lordosis After Multilevel Posterior Cervical Fusion Surgery. Spine (Phila Pa 1976). 2017;42:1859–64.CrossRef
4.
go back to reference Lan Z, Huang Y, Xu W. Relationship between T1 slope minus C2-7 Lordosis and cervical alignment parameters after adjacent 2-level anterior cervical Diskectomy and fusion of lower cervical spine. World Neurosurg. 2019;122:e1195–201.CrossRef Lan Z, Huang Y, Xu W. Relationship between T1 slope minus C2-7 Lordosis and cervical alignment parameters after adjacent 2-level anterior cervical Diskectomy and fusion of lower cervical spine. World Neurosurg. 2019;122:e1195–201.CrossRef
5.
go back to reference Xiong W, Zhou J, Sun C, Chen Z, Guo X, Huo X, et al. 0.5- to 1-Fold Intervertebral Distraction Is a Protective Factor for Adjacent Segment Degeneration in Single-level Anterior Cervical Discectomy and Fusion. Spine (Phila Pa 1976). 2020;45:96–102.CrossRef Xiong W, Zhou J, Sun C, Chen Z, Guo X, Huo X, et al. 0.5- to 1-Fold Intervertebral Distraction Is a Protective Factor for Adjacent Segment Degeneration in Single-level Anterior Cervical Discectomy and Fusion. Spine (Phila Pa 1976). 2020;45:96–102.CrossRef
6.
go back to reference Dong L, Xu Z, Chen X, Wang D, Li D, Liu T, et al. The change of adjacent segment after cervical disc arthroplasty compared with anterior cervical discectomy and fusion: a meta-analysis of randomized controlled trials. Spine J. 2017;17:1549–58.CrossRef Dong L, Xu Z, Chen X, Wang D, Li D, Liu T, et al. The change of adjacent segment after cervical disc arthroplasty compared with anterior cervical discectomy and fusion: a meta-analysis of randomized controlled trials. Spine J. 2017;17:1549–58.CrossRef
7.
go back to reference Di Martino A, Papalia R, Albo E, Cortesi L, Denaro L, Denaro V. Cervical spine alignment in disc arthroplasty: should we change our perspective? Eur Spine J. 2015;24:810–25.CrossRef Di Martino A, Papalia R, Albo E, Cortesi L, Denaro L, Denaro V. Cervical spine alignment in disc arthroplasty: should we change our perspective? Eur Spine J. 2015;24:810–25.CrossRef
8.
go back to reference Rihn JA, Radcliff K, Hipp J, Vaccaro AR, Hilibrand AS, Anderson DG, et al. Radiographic variables that may predict clinical outcomes in cervical disk replacement surgery. J Spinal Disord Tech. 2015;28:106–13.CrossRef Rihn JA, Radcliff K, Hipp J, Vaccaro AR, Hilibrand AS, Anderson DG, et al. Radiographic variables that may predict clinical outcomes in cervical disk replacement surgery. J Spinal Disord Tech. 2015;28:106–13.CrossRef
9.
go back to reference Hu L, Zhang J, Liu H, Meng Y, Yang Y, Li G, et al. Heterotopic ossification is related to change in disc space angle after Prestige-LP cervical disc arthroplasty. Eur Spine J. 2019;28:2359–70.CrossRef Hu L, Zhang J, Liu H, Meng Y, Yang Y, Li G, et al. Heterotopic ossification is related to change in disc space angle after Prestige-LP cervical disc arthroplasty. Eur Spine J. 2019;28:2359–70.CrossRef
10.
go back to reference Wu T-K, Meng Y, Wang B-Y, Hong Y, Rong X, Ding C, et al. Is the behavior of disc replacement adjacent to fusion affected by the location of the fused level in hybrid surgery? Spine J. 2018;18:2171–80.CrossRef Wu T-K, Meng Y, Wang B-Y, Hong Y, Rong X, Ding C, et al. Is the behavior of disc replacement adjacent to fusion affected by the location of the fused level in hybrid surgery? Spine J. 2018;18:2171–80.CrossRef
11.
go back to reference Wang X, Meng Y, Liu H, Chen H, Wang B, Hong Y. Association of cervical sagittal alignment with adjacent segment degeneration and heterotopic ossification following cervical disc replacement with Prestige-LP disc. J Orthop Surg. 2020;28:1–10. Wang X, Meng Y, Liu H, Chen H, Wang B, Hong Y. Association of cervical sagittal alignment with adjacent segment degeneration and heterotopic ossification following cervical disc replacement with Prestige-LP disc. J Orthop Surg. 2020;28:1–10.
12.
go back to reference Jin YJ, Park SB, Kim MJ, Kim K-J, Kim H-J. An analysis of heterotopic ossification in cervical disc arthroplasty: a novel morphologic classification of an ossified mass. Spine J. 2013;13:408–20.CrossRef Jin YJ, Park SB, Kim MJ, Kim K-J, Kim H-J. An analysis of heterotopic ossification in cervical disc arthroplasty: a novel morphologic classification of an ossified mass. Spine J. 2013;13:408–20.CrossRef
13.
go back to reference Zhou F, Ju KL, Zhao Y, Zhang F, Pan S, Heller JG, et al. Progressive Bone Formation After Cervical Disc Replacement. Spine (Phila Pa 1976). 2018;43:E163–70.CrossRef Zhou F, Ju KL, Zhao Y, Zhang F, Pan S, Heller JG, et al. Progressive Bone Formation After Cervical Disc Replacement. Spine (Phila Pa 1976). 2018;43:E163–70.CrossRef
14.
go back to reference Tu T-H, Lee C-Y, Kuo C-H, Wu J-C, Chang H-K, Fay L-Y, et al. Cervical disc arthroplasty for less-mobile discs. J Neurosurg Spine. 2019;31:310–6.CrossRef Tu T-H, Lee C-Y, Kuo C-H, Wu J-C, Chang H-K, Fay L-Y, et al. Cervical disc arthroplasty for less-mobile discs. J Neurosurg Spine. 2019;31:310–6.CrossRef
15.
go back to reference Ling FP, Chevillotte T, leglise A, Thompson W, Bouthors C, Le Huec JC. Which parameters are relevant in sagittal balance analysis of the cervical spine? A literature review. Eur Spine J. 2018;27:8–15.CrossRef Ling FP, Chevillotte T, leglise A, Thompson W, Bouthors C, Le Huec JC. Which parameters are relevant in sagittal balance analysis of the cervical spine? A literature review. Eur Spine J. 2018;27:8–15.CrossRef
16.
go back to reference Choi SH, Cho JH, Hwang CJ, Lee CS, Gwak HW, Lee D-H. Preoperative Radiographic Parameters to Predict a Higher Pseudarthrosis Rate After Anterior Cervical Discectomy and Fusion. Spine (Phila Pa 1976). 2017;42:1772–8.CrossRef Choi SH, Cho JH, Hwang CJ, Lee CS, Gwak HW, Lee D-H. Preoperative Radiographic Parameters to Predict a Higher Pseudarthrosis Rate After Anterior Cervical Discectomy and Fusion. Spine (Phila Pa 1976). 2017;42:1772–8.CrossRef
17.
go back to reference Gao X, Yang Y, Liu H, Meng Y, Zeng J, Wu T, et al. A comparison of cervical disc Arthroplasty and anterior cervical discectomy and fusion in patients with two-level cervical degenerative disc disease: 5-year follow-up results. World Neurosurg. 2019;122:e1083–9.CrossRef Gao X, Yang Y, Liu H, Meng Y, Zeng J, Wu T, et al. A comparison of cervical disc Arthroplasty and anterior cervical discectomy and fusion in patients with two-level cervical degenerative disc disease: 5-year follow-up results. World Neurosurg. 2019;122:e1083–9.CrossRef
18.
go back to reference Ryu WHA, Kowalczyk I, Duggal N. Long-term kinematic analysis of cervical spine after single-level implantation of Bryan cervical disc prosthesis. Spine J. 2013;13:628–34.CrossRef Ryu WHA, Kowalczyk I, Duggal N. Long-term kinematic analysis of cervical spine after single-level implantation of Bryan cervical disc prosthesis. Spine J. 2013;13:628–34.CrossRef
19.
go back to reference Rabin D, Bertagnoli R, Wharton N, Pickett GE, Duggal N. Sagittal balance influences range of motion: an in vivo study with the ProDisc-C. Spine J. 2009;9:128–33.CrossRef Rabin D, Bertagnoli R, Wharton N, Pickett GE, Duggal N. Sagittal balance influences range of motion: an in vivo study with the ProDisc-C. Spine J. 2009;9:128–33.CrossRef
20.
go back to reference Lee SE, Jahng TA, Kim HJ. Correlation between cervical lordosis and adjacent segment pathology after anterior cervical spinal surgery. Eur Spine J. 2015;24:2899–909.CrossRef Lee SE, Jahng TA, Kim HJ. Correlation between cervical lordosis and adjacent segment pathology after anterior cervical spinal surgery. Eur Spine J. 2015;24:2899–909.CrossRef
21.
go back to reference Pal GP, Sherk HH. The vertical stability of the cervical spine. Spine (Phila Pa 1976). 1988;13:447–9.CrossRef Pal GP, Sherk HH. The vertical stability of the cervical spine. Spine (Phila Pa 1976). 1988;13:447–9.CrossRef
22.
go back to reference Imagama S, Ando K, Kobayashi K, Machino M, Tanaka S, Morozumi M, Kanbara S, Ito S, Inoue T, Seki T, Ishizuka S, Nakashima H, Ishiguro N, Hasegawa Y. Impact of pelvic incidence on lumbar osteophyte formation and disc degeneration in middle-aged and elderly people in a prospective cross-sectional cohort. Eur Spine J. 2020;29(9):2262–71. https://doi.org/10.1007/s00586-019-06204-w. Epub 2020 Mar 4. Imagama S, Ando K, Kobayashi K, Machino M, Tanaka S, Morozumi M, Kanbara S, Ito S, Inoue T, Seki T, Ishizuka S, Nakashima H, Ishiguro N, Hasegawa Y. Impact of pelvic incidence on lumbar osteophyte formation and disc degeneration in middle-aged and elderly people in a prospective cross-sectional cohort. Eur Spine J. 2020;29(9):2262–71. https://​doi.​org/​10.​1007/​s00586-019-06204-w. Epub 2020 Mar 4.
23.
go back to reference Yang P, Li Y, Li J, Shen Y. Impact of T1 slope on surgical and adjacent segment degeneration after Bryan cervical disc arthroplasty. Ther Clin Risk Manag. 2017;13:1119–25.CrossRef Yang P, Li Y, Li J, Shen Y. Impact of T1 slope on surgical and adjacent segment degeneration after Bryan cervical disc arthroplasty. Ther Clin Risk Manag. 2017;13:1119–25.CrossRef
25.
go back to reference Guerin P, Obeid I, Gille O, Bourghli A, Luc S, Pointillart V, et al. Sagittal alignment after single cervical disc arthroplasty. J Spinal Disord Tech. 2012;25:10–6.CrossRef Guerin P, Obeid I, Gille O, Bourghli A, Luc S, Pointillart V, et al. Sagittal alignment after single cervical disc arthroplasty. J Spinal Disord Tech. 2012;25:10–6.CrossRef
26.
go back to reference Steinhaus ME, Iyer S, Lovecchio F, Stein D, Ross T, Yang J, et al. Which NDI domains best predict change in physical function in patients undergoing cervical spine surgery? Spine J. 2019;19:1698–705.CrossRef Steinhaus ME, Iyer S, Lovecchio F, Stein D, Ross T, Yang J, et al. Which NDI domains best predict change in physical function in patients undergoing cervical spine surgery? Spine J. 2019;19:1698–705.CrossRef
Metadata
Title
Cervical sagittal alignment after Prestige LP cervical disc replacement: radiological results and clinical impacts from a single-center experience
Authors
Xiaofei Wang
Yang Meng
Hao Liu
Hua Chen
Beiyu Wang
Ying Hong
Publication date
01-12-2021
Publisher
BioMed Central
Published in
BMC Musculoskeletal Disorders / Issue 1/2021
Electronic ISSN: 1471-2474
DOI
https://doi.org/10.1186/s12891-021-03962-x

Other articles of this Issue 1/2021

BMC Musculoskeletal Disorders 1/2021 Go to the issue