Skip to main content
Top
Published in: Journal of Medical Case Reports 1/2008

Open Access 01-12-2008 | Case report

Cervical lymphadenopathy – an unusual presentation of carcinoma of the cervix: a case report

Authors: Madhavi Manoharan, Durga Satyanarayana, Arjun R Jeyarajah

Published in: Journal of Medical Case Reports | Issue 1/2008

Login to get access

Abstract

Introduction

The clinical presentation of carcinoma of the cervix as cervical lymphadenopathy has not been described before. We report a case of this unusual manifestation of cervical cancer.

Case presentation

A 51-year-old woman presented to our Head and Neck department with cervical lymphadenopathy. A positron emission tomography scan revealed the primary tumour to be in the cervix and a cervical biopsy confirmed carcinoma of the cervix.

Conclusion

Recurrences of carcinoma of the cervix presenting as lymphadenopathy have been described before but this is the first time a clinical presentation of carcinoma of the cervix as cervical lymphadenopathy has been described. Although metastasis from the cervix to the cervical lymph nodes is rare, this can be explained by outlining the drainage of the lymphatic system from the cervix.
Appendix
Available only for authorised users
Literature
1.
go back to reference Ellison E, LaPuerta P, Martin SE: Supraclavicular masses: results of a series of 309 cases biopsied by fine needle aspiration. Head Neck. 1999, 21 (3): 239-246. 10.1002/(SICI)1097-0347(199905)21:3<239::AID-HED9>3.0.CO;2-B.CrossRefPubMed Ellison E, LaPuerta P, Martin SE: Supraclavicular masses: results of a series of 309 cases biopsied by fine needle aspiration. Head Neck. 1999, 21 (3): 239-246. 10.1002/(SICI)1097-0347(199905)21:3<239::AID-HED9>3.0.CO;2-B.CrossRefPubMed
2.
go back to reference Henriksen E: Lymphatic spread of carcinoma of cervix and body of uterus. Am J Obstet Gynecol. 1949, 58: 924CrossRefPubMed Henriksen E: Lymphatic spread of carcinoma of cervix and body of uterus. Am J Obstet Gynecol. 1949, 58: 924CrossRefPubMed
3.
go back to reference Shin MS, Shingleton HM, Partridge EE, Nicolson VM, Ho KJ: Squamous cell carcinoma of the uterine cervix. Patterns of thoracic metastases. Invest Radiol. 1995, 30 (12): 724-729. 10.1097/00004424-199512000-00006.CrossRefPubMed Shin MS, Shingleton HM, Partridge EE, Nicolson VM, Ho KJ: Squamous cell carcinoma of the uterine cervix. Patterns of thoracic metastases. Invest Radiol. 1995, 30 (12): 724-729. 10.1097/00004424-199512000-00006.CrossRefPubMed
4.
go back to reference Scott I, Bergin CJ, Muller NL: Mediastinal and hilar lymphadenopathy as the only manifestation of metastatic carcinoma of the cervix. Can Assoc Radiol J. 1986, 37 (1): 52-53.PubMed Scott I, Bergin CJ, Muller NL: Mediastinal and hilar lymphadenopathy as the only manifestation of metastatic carcinoma of the cervix. Can Assoc Radiol J. 1986, 37 (1): 52-53.PubMed
5.
go back to reference Diddle AW: Carcinoma of the cervix uteri with metastases to the neck. Cancer. 1972, 29 (2): 453-455. 10.1002/1097-0142(197202)29:2<453::AID-CNCR2820290230>3.0.CO;2-7.CrossRefPubMed Diddle AW: Carcinoma of the cervix uteri with metastases to the neck. Cancer. 1972, 29 (2): 453-455. 10.1002/1097-0142(197202)29:2<453::AID-CNCR2820290230>3.0.CO;2-7.CrossRefPubMed
6.
go back to reference Warburg O: The Metabolism of Tumours. 1931, New York, NY: Richard R. Smith Inc, 129-169. Warburg O: The Metabolism of Tumours. 1931, New York, NY: Richard R. Smith Inc, 129-169.
7.
go back to reference Kumar R, Chauhan A, Jana S, Dadparvar S: Positron emission tomography in gynecological malignancies. Expert Rev Anticancer Ther. 2006, 6 (7): 1033-1044. 10.1586/14737140.6.7.1033.CrossRefPubMed Kumar R, Chauhan A, Jana S, Dadparvar S: Positron emission tomography in gynecological malignancies. Expert Rev Anticancer Ther. 2006, 6 (7): 1033-1044. 10.1586/14737140.6.7.1033.CrossRefPubMed
8.
go back to reference Guntinas-Lichius O, Klissmann JP, Dinh S, Dinh M, Schmidt M, Semrau R, Mueller RP: Diagnostic work up and outcome of cervical metastases from an unknown primary. Acta Otolaryngol. 2006, 126 (5): 536-544. 10.1080/00016480500417304.CrossRefPubMed Guntinas-Lichius O, Klissmann JP, Dinh S, Dinh M, Schmidt M, Semrau R, Mueller RP: Diagnostic work up and outcome of cervical metastases from an unknown primary. Acta Otolaryngol. 2006, 126 (5): 536-544. 10.1080/00016480500417304.CrossRefPubMed
9.
go back to reference Regelink G, Brouwer J, de Bree R, Pruim J, Laan van der BF, Vaalburg W, Hoekstra OS, Comans EF, Vissink A, Leemans CR, Roodenburg JL: Detection of unknown primary tumours and distant metastases in patients with cervical metastases: value of FDG-PET versus conventional modalities. Eur J Nucl Med Mol Imaging. 2002, 29 (8): 1024-1030. 10.1007/s00259-002-0819-0.CrossRefPubMed Regelink G, Brouwer J, de Bree R, Pruim J, Laan van der BF, Vaalburg W, Hoekstra OS, Comans EF, Vissink A, Leemans CR, Roodenburg JL: Detection of unknown primary tumours and distant metastases in patients with cervical metastases: value of FDG-PET versus conventional modalities. Eur J Nucl Med Mol Imaging. 2002, 29 (8): 1024-1030. 10.1007/s00259-002-0819-0.CrossRefPubMed
10.
go back to reference Trinh XB, Bogers JJ, Van Marck EA, Tjalma WA: Treatment policy of neuroendocrine small cell cancer of the cervix. Eur J Gynaecol Oncol. 2004, 25 (1): 40-44.PubMed Trinh XB, Bogers JJ, Van Marck EA, Tjalma WA: Treatment policy of neuroendocrine small cell cancer of the cervix. Eur J Gynaecol Oncol. 2004, 25 (1): 40-44.PubMed
11.
go back to reference Carlson V, Delclos L, Fletcher GH: Distant metastases in squamous cell carcinoma of the uterine cervix. Radiology. 1967, 88: 961-966.CrossRefPubMed Carlson V, Delclos L, Fletcher GH: Distant metastases in squamous cell carcinoma of the uterine cervix. Radiology. 1967, 88: 961-966.CrossRefPubMed
12.
go back to reference Moore DH, Blessing JA, McQuellon RP, Thaler HT, Cella D, Benda J, Miller DS, Olt G, King S, Boggess JF, Rocereto TF: Phase III study of cisplatin with or without paclitaxel in stage IVB, recurrent, or persistent squamous cell carcinoma of the cervix: a gynaecologic oncology group study. J Clin Oncol. 2004, 22 (15): 3113-3119. 10.1200/JCO.2004.04.170.CrossRefPubMed Moore DH, Blessing JA, McQuellon RP, Thaler HT, Cella D, Benda J, Miller DS, Olt G, King S, Boggess JF, Rocereto TF: Phase III study of cisplatin with or without paclitaxel in stage IVB, recurrent, or persistent squamous cell carcinoma of the cervix: a gynaecologic oncology group study. J Clin Oncol. 2004, 22 (15): 3113-3119. 10.1200/JCO.2004.04.170.CrossRefPubMed
13.
go back to reference Tewari KS, Monk BJ: Gynecologic oncology group trials of chemotherapy for metastatic and recurrent cervical cancer. Curr Oncol Rep. 2005, 7 (6): 419-434. 10.1007/s11912-005-0007-z.CrossRefPubMed Tewari KS, Monk BJ: Gynecologic oncology group trials of chemotherapy for metastatic and recurrent cervical cancer. Curr Oncol Rep. 2005, 7 (6): 419-434. 10.1007/s11912-005-0007-z.CrossRefPubMed
Metadata
Title
Cervical lymphadenopathy – an unusual presentation of carcinoma of the cervix: a case report
Authors
Madhavi Manoharan
Durga Satyanarayana
Arjun R Jeyarajah
Publication date
01-12-2008
Publisher
BioMed Central
Published in
Journal of Medical Case Reports / Issue 1/2008
Electronic ISSN: 1752-1947
DOI
https://doi.org/10.1186/1752-1947-2-252

Other articles of this Issue 1/2008

Journal of Medical Case Reports 1/2008 Go to the issue