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Indian Journal of Hematology and Blood Transfusion

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01-06-2016 | Case Report

CD5 Positive B Lymphoblastic Leukemia: Report of a Case with Review of Literature

Authors: Sreejesh Sreedharanunni, Narender Kumar, Alka Khadwal

Published in: Indian Journal of Hematology and Blood Transfusion | Special Issue 1/2016

Abstract

We report a rare CD5 positive B cell acute lymphoblastic leukemia (B-ALL) with a review of the clinopathological features and prognosis of previously reported cases in the literature. The aberrant expression of CD 5 antigen is uncommon in B-ALL; the morphological differential diagnosis includes blastic mantle cell lymphoma, denovo CD5⁺ diffuse large B cell lymphoma and secondary diffuse large cell lymphoma/Richter’s transformation. CD5⁺ B cell ALL is commonly reported in younger patients (<18 years). Though the expression of T cell antigens is reported to have poor prognosis, the experience with CD5⁺ B-ALL is limited to draw any firm conclusion regarding its prognosis.

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Title: CD5 Positive B Lymphoblastic Leukemia: Report of a Case with Review of Literature
Authors: Sreejesh Sreedharanunni
Narender Kumar
Alka Khadwal
Publication date: 01-06-2016
Publisher: Springer India
Published in: Indian Journal of Hematology and Blood Transfusion / Issue Special Issue 1/2016
Print ISSN: 0971-4502
Electronic ISSN: 0974-0449
DOI: https://doi.org/10.1007/s12288-014-0485-y

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