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Published in: CardioVascular and Interventional Radiology 2/2008

01-07-2008 | Case Report

Catheter-Directed Thrombolysis of Inferior Vena Cava Thrombosis in a 13-Day-Old Neonate and Review of Literature

Authors: Jawad U. Khan, Clifford M. Takemoto, James F. Casella, Michael B. Streiff, Ikechi J. Nwankwo, Hyun S. Kim

Published in: CardioVascular and Interventional Radiology | Special Issue 2/2008

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Abstract

Complete inferior vena cava thrombosis (IVC) in neonates is uncommon, but may cause significant morbidity. A 13-day-old neonate suffered IVC thrombosis secondary to antithrombin III deficiency, possibly contributed to by a mutation in the methyl tetrahydrofolate reductase gene. Catheter-directed thrombolysis (CDT) with recombinant tissue plasminogen activator (rt-PA, Alteplase) was used successfully to treat extensive venous thrombosis in this neonate without complications. We also review the literature on CDT for treatment of IVC thrombosis in critically ill neonates and infants.
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Metadata
Title
Catheter-Directed Thrombolysis of Inferior Vena Cava Thrombosis in a 13-Day-Old Neonate and Review of Literature
Authors
Jawad U. Khan
Clifford M. Takemoto
James F. Casella
Michael B. Streiff
Ikechi J. Nwankwo
Hyun S. Kim
Publication date
01-07-2008
Publisher
Springer-Verlag
Published in
CardioVascular and Interventional Radiology / Issue Special Issue 2/2008
Print ISSN: 0174-1551
Electronic ISSN: 1432-086X
DOI
https://doi.org/10.1007/s00270-007-9229-9

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