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International Ophthalmology

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Open Access 01-12-2024 | Cataract | Original Paper

Visual performance and patient preference with bilateral implantation of an extended depth of focus or combined implantation of an extended depth of focus/trifocal intraocular lens

Authors: Jonathan Moore, Jens Østergaard, Florian Kretz

Published in: International Ophthalmology | Issue 1/2024

Abstract

Purpose

Evaluate postoperative visual performance in patients with bilaterally implanted AT LARA or AT LARA/AT LISA tri (Carl Zeiss AG, Jena, Germany) intraocular lenses.

Methods

Multicentered, comparative, open-label, retrospective/prospective study. Post-IOL implantation, patients were prospectively enrolled into this study; preoperative patient data were collected retrospectively. Follow-up was at 2–4 and 5–8 months post-surgery. The primary endpoint was binocular best corrected distance visual acuity (CDVA). The study was retrospectively registered on clinicaltrials.gov (#NCT05462067).

Results

Seventy-one patients (142 eyes) were enrolled; 67 patients (134 eyes) have 5–8 months data. The mean binocular CDVA at 2–4 months was -0.10 ± 0.06 logMAR in the bilateral AT LARA group (“bilateral”) and -0.11 ± 0.09 logMAR in the combined implantation AT LARA/ AT LISA tri group (“combined implantation”); (P = 0.4856). At 5–8 months, mean binocular CDVA was -0.13 ± 0.06 logMAR in the bilateral group and -0.11 ± 0.09 in the combined implantation group (P = 0.4003). At 5–8 months, more eyes in the bilateral group attained 0.2 logMAR or better binocular uncorrected intermediate VA (UIVA; 67 cm) than those in the combined implantation group (100% vs. 94%, respectively). The bilateral group achieved a mean of 0.24 ± 0.11 logMAR in uncorrected near VA (UCNVA), compared to a mean of 0.16 ± 0.12 logMAR in the combined implantation group at 5–8 months (P = 0.0041).

Conclusions

A combined implantation approach (AT LARA in the distance dominant eye/AT LISA tri in the non-dominant eye) produced similar CDVA outcomes but better UCNVA as bilateral implantation with the AT LARA. UIVA was comparable between groups. No new safety concerns were reported.

Sample size calculations can be determined online from Sealed Envelope. Available from: https://www.sealedenvelope.com/power/continuous-noninferior/ [Accessed Mon Nov 05 2018].

Acar B, Nurozler Tabakci B (2021) Clinical outcome comparison: bilateral trifocal vs mix-match extended depth of focus and trifocal intraocular lenses. Int Ophthalmol 41(11):3675–3686. https://doi.org/10.1007/s10792-021-01925-8CrossRefPubMed

Ganesh S, Brar S, Pawar A (2017) Long-term visual outcomes and patient satisfaction following bilateral implantation of trifocal intraocular lenses. Clin Ophthalmol 11:1453–1459. https://doi.org/10.2147/OPTH.S125921CrossRefPubMedPubMedCentral

Iradier MT, Cruz V, Gentile N, Cedano P, Pinero DP (2021) Clinical outcomes with a novel extended depth of focus presbyopia-correcting intraocular lens: pilot study. Clin Ophthalmol 15:1215–1221. https://doi.org/10.2147/OPTH.S297985CrossRefPubMedPubMedCentral

Vilar C, Hida WT, de Medeiros AL et al (2017) Comparison between bilateral implantation of a trifocal intraocular lens and blended implantation of two bifocal intraocular lenses. Clin Ophthalmol 11:1393–1397. https://doi.org/10.2147/OPTH.S139909CrossRefPubMedPubMedCentral

Cochener B, Vryghem J, Rozot P et al (2014) Clinical outcomes with a trifocal intraocular lens: a multicenter study. J Refract Surg 30(11):762–768. https://doi.org/10.3928/1081597X-20141021-08CrossRefPubMed

Jin S, Friedman DS, Cao K et al (2019) Comparison of postoperative visual performance between bifocal and trifocal intraocular Lens based on randomized controlled trails: a meta-analysis. BMC Ophthalmol 19(1):78. https://doi.org/10.1186/s12886-019-1078-1CrossRefPubMedPubMedCentral

Son HS, Tandogan T, Liebing S et al (2017) In vitro optical quality measurements of three intraocular lens models having identical platform. BMC Ophthalmol 17(1):108. https://doi.org/10.1186/s12886-017-0460-0CrossRefPubMedPubMedCentral

Carson D, Hill WE, Hong X, Karakelle M (2014) Optical bench performance of AcrySof((R)) IQ ReSTOR((R)), AT LISA((R)) tri, and FineVision((R)) intraocular lenses. Clin Ophthalmol 8:2105–2113. https://doi.org/10.2147/OPTH.S66760CrossRefPubMedPubMedCentral

Song JE, Han SY, Khoramnia R, Tandogan T, Auffarth GU, Choi CY (2021) Clinical outcomes of combined implantation of an extended depth of focus IOL and a trifocal IOL in a Korean population. J Ophthalmol 2021:9034258. https://doi.org/10.1155/2021/9034258CrossRefPubMedPubMedCentral

10.

Kanclerz P, Toto F, Grzybowski A, Alio JL (2020) Extended depth-of-field intraocular lenses: an update. Asia Pac J Ophthalmol (Phila). 9(3):194–202. https://doi.org/10.1097/APO.0000000000000296CrossRefPubMed

11.

McNeely RN, Moutari S, Palme C, Moore JE (2020) Visual outcomes and subjective experience after combined implantation of extended depth of focus and trifocal IOLs. J Refract Surg 36(5):326–333. https://doi.org/10.3928/1081597X-20200318-01CrossRefPubMed

12.

Mencucci R, Favuzza E, Caporossi O, Savastano A, Rizzo S (2018) Comparative analysis of visual outcomes, reading skills, contrast sensitivity, and patient satisfaction with two models of trifocal diffractive intraocular lenses and an extended range of vision intraocular lens. Graefes Arch Clin Exp Ophthalmol 256(10):1913–1922. https://doi.org/10.1007/s00417-018-4052-3CrossRefPubMed

13.

Tarib I, Diakonis VF, Breyer D, Hohn F, Hahn U, Kretz FTA (2019) Outcomes of combining a trifocal and a low-addition bifocal intraocular lens in patients seeking spectacle independence at all distances. J Cataract Refract Surg 45(5):620–629. https://doi.org/10.1016/j.jcrs.2019.01.013CrossRefPubMed

14.

Tarib I, Kasier I, Herbers C et al (2019) Comparison of visual outcomes and patient satisfaction after bilateral implantation of an EDOF IOL and a mix-and-match approach. J Refract Surg 35(7):408–416. https://doi.org/10.3928/1081597X-20190417-02CrossRefPubMed

15.

Poyales F, Garzón N, Poyales C, Poyales B (2018) Clinical outcomes with a new model of extended depth of focus intraocular lens. Open J Ophthalmol 08(03):161–170. https://doi.org/10.4236/ojoph.2018.83020CrossRef

16.

Kim JW, Eom Y, Yoon EG et al (2021) Increased near vision spectacle dependence of patients with preoperative myopia after mix-and-match implantation of trifocal EDOF and trifocal IOLs. J Refract Surg 37(11):746–753. https://doi.org/10.3928/1081597X-20210802-02CrossRefPubMed

17.

McAlinden C, Pesudovs K, Moore JE (2010) The development of an instrument to measure quality of vision: the quality of vision (QoV) questionnaire. Invest Ophthalmol Vis Sci 51(11):5537–5545. https://doi.org/10.1167/iovs.10-5341CrossRefPubMed

18.

Kohnen T, Titke C, Bohm M (2016) Trifocal intraocular lens implantation to treat visual demands in various distances following lens removal. Am J Ophthalmol 161(71–7):e1. https://doi.org/10.1016/j.ajo.2015.09.030CrossRef

19.

Breyer DRH, Kaymak H, Ax T, Kretz FTA, Auffarth GU, Hagen PR (2017) Multifocal intraocular lenses and extended depth of focus intraocular lenses. Asia Pac J Ophthalmol (Phila). 6(4):339–349. https://doi.org/10.22608/APO.2017186CrossRefPubMed

20.

Webers VSC, Bauer NJC, Saelens IEY et al (2020) Comparison of the intermediate distance of a trifocal IOL with an extended depth-of-focus IOL: results of a prospective randomized trial. J Cataract Refract Surg 46(2):193–203. https://doi.org/10.1097/j.jcrs.0000000000000012CrossRefPubMed

21.

Koo OS, Kang JW, Park JK, Kim KH (2021) Visual performance and patient satisfaction after implantation of extended range-of-vision IOLs: bilateral implantation vs 2 different mix-and-match approaches. J Cataract Refract Surg 47(2):192–197. https://doi.org/10.1097/j.jcrs.0000000000000424CrossRefPubMed

22.

McNeely RN, Moutari S, Stewart S, Moore JE (2021) Visual outcomes and patient satisfaction 1 and 12 months after combined implantation of extended depth of focus and trifocal intraocular lenses. Int Ophthalmol 41(12):3985–3998. https://doi.org/10.1007/s10792-021-01970-3CrossRefPubMedPubMedCentral

23.

Schallhorn SC, Teenan D, Venter JA, Hannan SJ, Schallhorn JM (2019) Initial clinical outcomes of a new extended depth of focus intraocular lens. J Refract Surg 35(7):426–433. https://doi.org/10.3928/1081597X-20190530-01CrossRefPubMed

24.

Rodov L, Reitblat O, Levy A, Assia EI, Kleinmann G (2019) Visual outcomes and patient satisfaction for trifocal, extended depth of focus and monofocal intraocular lenses. J Refract Surg 35(7):434–440. https://doi.org/10.3928/1081597X-20190618-01CrossRefPubMed

Title: Visual performance and patient preference with bilateral implantation of an extended depth of focus or combined implantation of an extended depth of focus/trifocal intraocular lens
Authors: Jonathan Moore
Jens Østergaard
Florian Kretz
Publication date: 01-12-2024
Publisher: Springer Netherlands
Keyword: Cataract
Published in: International Ophthalmology / Issue 1/2024
Print ISSN: 0165-5701
Electronic ISSN: 1573-2630
DOI: https://doi.org/10.1007/s10792-024-03030-y

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Visual performance and patient preference with bilateral implantation of an extended depth of focus or combined implantation of an extended depth of focus/trifocal intraocular lens

Abstract

Purpose

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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