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Graefe's Archive for Clinical and Experimental Ophthalmology

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01-12-2019 | Cataract | Refractive Surgery

Long-term endothelial cell loss with the iris-claw intraocular phakic lenses (Artisan®)

Authors: Virgilio Galvis, John F. Villamil, María Fernanda Acuña, Paul A. Camacho, Jesús Merayo-Lloves, Alejandro Tello, Sandra Lizeth Zambrano, Juan José Rey, Juan Vicente Espinoza, Angélica María Prada

Published in: Graefe's Archive for Clinical and Experimental Ophthalmology | Issue 12/2019

Abstract

Purpose

To evaluate the endothelial cell loss in patients with iris-claw phakic lenses (Artisan®) in a long-term follow-up.

Methods

We analyzed the medical records of patients who had undergone iris-claw phakic lens implantation and who had at least 5 years of follow-up.

Results

We included 67 eyes with myopic errors (follow-up 9.6 ± 3.0 years) and 10 eyes with mixed astigmatism or hyperopic errors (follow-up 8.8 ± 2.5 years). The mean total endothelial density loss at the last follow-up visit was 18.5% ± 17.0% and 10.5% ± 12.3%, respectively. 29.9% of the eyes in the myopic group and 20% in the hyperopic group lost more than 25% of the preoperative endothelial cell density. During the postoperative follow-up period, 60.8% of the eyes in the myopic group and 40% of the eyes in the hyperopic group lost a higher percentage than the expected physiological loss. Two eyes in the myopic group (3.0%) had a final cell density of less than 1200 cells/mm². None of the variables studied had a statistically significant association with the percentage of annual endothelial loss in the postoperative period. Three phakic lenses were explanted: two by cataract and one by cataract and severe decrease of the endothelial density (862 cells/mm²).

Conclusions

There is a significant endothelial cell loss in a low percentage of the eyes with Artisan® lenses in the long term, and it can decrease to critical levels. Periodic endothelial density evaluations are required for these patients. The selection criteria of surgical candidates could be reevaluated.

Alió JL, Soria F, Abbouda A, Peña-García P (2015) Laser in situ keratomileusis for -6.00 to -18.00 diopters of myopia and up to -5.00 diopters of astigmatism: 15-year follow-up. J Cataract Refract Surg 41:33–40. https://doi.org/10.1016/j.jcrs.2014.08.029 CrossRefPubMed

Vega-Estrada A, Alió JL, Arba Mosquera S, Moreno LJ (2012) Corneal higher order aberrations after LASIK for high myopia with a fast repetition rate excimer laser, optimized ablation profile, and femtosecond laser-assisted flap. J Refract Surg 28:689–696. https://doi.org/10.3928/1081597X-20120921-03 CrossRefPubMed

Santhiago MR (2016) Percent tissue altered and corneal ectasia. Curr Opin Ophthalmol 27:311–315. https://doi.org/10.1097/ICU.0000000000000276 CrossRefPubMed

Pineda R 2nd, Chauhan T (2016) Phakic intraocular lenses and their special indications. J Ophthalmic Vis Res 11:422–428CrossRef

Alió JL, Toffaha BT (2013) Refractive surgery with phakic intraocular lenses: an update. Int Ophthalmol Clin 53:91–110. https://doi.org/10.1097/IIO.0b013e318272d27b CrossRefPubMed

Kohnen T (2018) Phakic intraocular lenses: where are we now? J Cataract Refract Surg 44:121–123. https://doi.org/10.1016/j.jcrs.2018.03.005 CrossRefPubMed

Kohnen T, Kook D, Morral M, Güell JL (2010) Phakic intraocular lenses: part 2: results and complications. J Cataract Refract Surg 36:2168–2194. https://doi.org/10.1016/j.jcrs.2010.10.007 CrossRefPubMed

Pechméja J, Guinguet J, Colin J, Binder PS (2012) Severe endothelial cell loss with anterior chamber phakic intraocular lenses. J Cataract Refract Surg 38:1288–1292. https://doi.org/10.1016/j.jcrs.2012.04.022 CrossRefPubMed

Galvis V, Tello A, Carreño NI, Berrospi RD, Niño CA, Cuadros MO (2017) Endothelial loss with AcrySof® Cachet® angle-supported phakic lens. Arch Soc Esp Oftalmol 92:e53–e54. https://doi.org/10.1016/j.oftal.2016.11.020 CrossRefPubMed

10.

Alió JL, Abbouda A, Peña-Garcia P, Huseynli S (2013) Follow-up study of more than 15 years of an angle-supported phakic intraocular lens model (ZB5M) for high myopia outcomes and complications. JAMA Ophthalmol 131:1541–1546. https://doi.org/10.1001/jamaophthalmol.2013.5595 CrossRefPubMed

11.

Alio JL, Toffaha BT, Peña-Garcia P, Sádaba LM, Barraquer RI (2015) Phakic intraocular lens explantation: causes in 240 cases. J Refract Surg 31:30–35. https://doi.org/10.3928/1081597X-20141202-01 CrossRefPubMed

12.

Sayman Muslubas IB, Kandemir B, Aydin Oral AY, Kugu S, Dastan M (2014) Long-term vision-threatening complications of phakic intraocular lens implantation for high myopia. Int J Ophthalmol 7:376–380. https://doi.org/10.3980/j.issn.2222-3959.2014.02.32 CrossRefPubMedPubMedCentral

13.

Fechner PU, Worst JGF (1989) A new concave intraocular lens for the correction of myopia. Eur J Implant Refract Surg 1:41–43. https://doi.org/10.1016/S0955-3681(89)80034-6 CrossRef

14.

Worst JGF, Van der Veen G, Los LI (1990) Refractive surgery for high myopia. The Worst-Fechner biconcave iris claw lens. Doc Ophthalmol 75:335–341CrossRef

15.

Fechner PU, Haubitz I, Wichmann W, Wulff K (1999) Worst-Fechner biconcave minus power phakic iris-claw lens. J Refract Surg 15:93–105PubMed

16.

Landesz M, Worst JG, van Rij G (2000) Long-term results of correction of high myopia with an iris claw phakic intraocular lens. J Refract Surg 16:310–316. https://doi.org/10.3928/1081-597X-20000501-03 CrossRefPubMed

17.

Güell JL, Morral M, Gris O, Gaytan J, Sisquella M, Manero F (2008) Five-year follow-up of 399 phakic Artisan-Verisyse implantation for myopia, hyperopia, and/or astigmatism. Ophthalmology 115:1002–1012. https://doi.org/10.1016/j.ophtha.2007.08.022 CrossRefPubMed

18.

Benedetti S, Casamenti V, Benedetti M (2007) Long-term endothelial changes in phakic eyes after Artisan intraocular lens implantation to correct myopia. Five-year study. J Cataract Refract Surg 33:784–790. https://doi.org/10.1016/j.jcrs.2007.01.037 CrossRefPubMed

19.

Menezo JL, Peris-Martínez C, Cisneros AL, Martínez-Costa R (2004) Phakic intraocular lenses to correct high myopia: Adatomed, Staar, and Artisan. J Cataract Refract Surg 30:33–44. https://doi.org/10.1016/j.jcrs.2003.11.023 CrossRefPubMed

20.

Silva RA, Jain A, Manche EE (2008) Prospective long-term evaluation of the efficacy, safety, and stability of the phakic intraocular lens for high myopia. Arch Ophthalmol 126:775–781. https://doi.org/10.1001/archopht.126.6.775 CrossRefPubMed

21.

Tahzib NG, Nuijts RM, Wu WY, Budo CJ (2007) Long-term study of Artisan phakic intraocular lens implantation for the correction of moderate to high myopia. Ten-Year Follow-up Results. Ophthalmology 114:1133–1142. https://doi.org/10.1016/j.ophtha.2006.09.029 CrossRefPubMed

22.

Stulting RD, John ME, Maloney RK, Assil KK, Arrowsmith PN, Thompson VM (2008) Three-year results of Artisan/Verisyse phakic intraocular lens implantation. Results of the United States Food and Drug Administration Clinical Trial. Ophthalmology 115:464–472. https://doi.org/10.1016/j.ophtha.2007.08.039 CrossRefPubMed

23.

Jonker SMR, Berendschot TTJM, Ronden AE, Saelens IEY, Bauer NJC, Nuijts RMMA (2018) Long-term endothelial cell loss in patients with Artisan myopia and Artisan toric phakic intraocular lenses: 5- and 10-year results. Ophthalmology 125:486–494. https://doi.org/10.1016/j.ophtha.2017.08.011 CrossRefPubMed

24.

Chebli S, Rabilloud M, Burillon C, Kocaba V (2018) Corneal endothelial tolerance after iris-fixated phakic intraocular lens implantation: a model to predict endothelial cell survival. Cornea 37:591–595. https://doi.org/10.1097/ICO.0000000000001527 CrossRefPubMed

25.

Sanders DR (2008) Anterior subcapsular opacities and cataracts 5 years after surgery in the Visian Implantable Collamer lens FDA trial. J Refract Surg 24:566–570. https://doi.org/10.3928/1081597X-20080601-04 CrossRefPubMed

26.

Packer M (2016) Meta-analysis and review: effectiveness, safety, and central port design of the intraocular collamer lens. Clin Ophthalmol 10:1059–1077. https://doi.org/10.2147/OPTH.S111620 CrossRefPubMedPubMedCentral

27.

Moya T, Javaloy J, Montés-Micó R, Beltrán J, Muñoz G, Montalbán R (2015) Implantable Collamer lens for myopia: assessment 12 years after implantation. J Refract Surg 31:548–556. https://doi.org/10.3928/1081597X-20150727-05 CrossRefPubMed

28.

Moya T, Javaloy J, Montés-Micó R, Beltrán J, Muñoz G, Montalbán R (2015) Reply: to. J Refract Surg 31:854-855CrossRef

29.

Alfonso JF, Fernández-Vega-Cueto L, Alfonso-Bartolozzi B, Montés-Micó R, Fernández-Vega L (2019) Five-year follow-up of correction of myopia: posterior chamber phakic intraocular lens with a central port design. J Refract Surg 35:169–176. https://doi.org/10.3928/1081597X-20190118-01 CrossRefPubMed

30.

Bourne WM, Nelson LR, Hodge DO (1997) Central corneal endothelial cell changes over a ten-year period. Invest Ophthalmol Vis Sci 38:779–782PubMed

31.

Gierek-Ciaciura S, Gierek-Lapinska A, Ochalik K, Mrukwa-Kominek E (2007) Correction of high myopia with different phakic anterior chamber intraocular lenses: ICARE angle-supported lens and Verisyse iris-claw lens. Graefes Arch Clin Exp Ophthalmol 245:1–7. https://doi.org/10.1007/s00417-006-0374-7 CrossRefPubMed

32.

Budo C, Hessloehl JC, Izak M, Luyten GP, Menezo JL, Sener BA, Tassignon MJ, Termote H, Worst JG (2000) Multicenter study of the Artisan phakic intraocular lens. J Cataract Refract Surg 26:1163–1171CrossRef

33.

Landesz M, van Rij G, Luyten G (2001) Iris-claw phakic intraocular lens for high myopia. J Refract Surg 17:634–640PubMed

34.

Lifshitz T, Levy J, Aizenman I, Klemperer I, Levinger S (2004) Artisan phakic intraocular lens for correcting high myopia. Int Ophthalmol 25:233–238. https://doi.org/10.1007/s10792-005-5016-2 CrossRefPubMed

35.

Maloney RK, Nguyen LH, John ME (2002) Artisan phakic intraocular lens for myopia short-term results of a prospective, multicenter study. Ophthalmology 109:1631–1641CrossRef

36.

Malecaze FJ, Hulin H, Bierer P, Fournié P, Grandjean H, Thalamas C, Guell JL (2002) A randomized paired eye comparison of two techniques for treating moderately high myopia: LASIK and artisan phakic lens. Ophthalmology 109:1622–1630CrossRef

37.

Benedetti S, Casamenti V, Marcaccio L, Brogioni C, Assetto V (2005) Correction of myopia of 7 to 24 diopters with the Artisan phakic in traocular lens: two-year follow-up. J Refract Surg 21:116–126PubMed

38.

Senthil S, Reddy KP (2006) A retrospective analysis of the first Indian experience on Artisan phakic intraocular lens. Indian J Ophthalmol 54:251–255. https://doi.org/10.4103/0301-4738.27950 CrossRefPubMed

39.

Hassaballa MA, Macky TA (2011) Phakic intraocular lenses outcomes and complications: Artisan vs Visian ICL. Eye (Lond) 25:1365–1370CrossRef

40.

Moshirfar M, Imbornoni LM, Ostler EM, Muthappan V (2014) Incidence rate and occurrence of visually significant cataract formation and corneal decompensation after implantation of Verisyse/Artisan phakic intraocular lens. Clin Ophthalmol 8:711–716. https://doi.org/10.2147/OPTH.S59878 CrossRefPubMedPubMedCentral

41.

Van Eijden R, de Vries NE, Cruysberg LP, Webers CA, Berenschot T, Nuijts RM (2009) Case of late-onset corneal decompensation after iris-claw phakic intraocular lens implantation. J Cataract Refract Surg 35:774–777. https://doi.org/10.1016/j.jcrs.2008.09.032 CrossRefPubMed

42.

Kim M, Kim JK, Lee HK (2008) Corneal endothelial decompensation after iris-claw phakic intraocular lens implantation. J Cataract Refract Surg 34:517–519. https://doi.org/10.1016/j.jcrs.2007.10.030 CrossRefPubMed

43.

Sikder S, Patel V, Holz HA, Mifflin MD, Davis S, Moshirfar M (2011) Management of corneal endothelial decompensation caused by iris-claw phakic intraocular lenses with descemet stripping automated endothelial keratoplasty. Cornea 30:1045–1047. https://doi.org/10.1097/ICO.0b013e3182035dd0 CrossRefPubMed

44.

Saxena R, Boekhoorn SS, Mulder PGH, Noordxij B, van Rij G, Luyten GP (2008) Long-term follow-up of endothelial cell change after Artisan phakic intraocular lens implantation. Ophthalmology 115:608–613. https://doi.org/10.1016/j.ophtha.2007.05.036 CrossRefPubMed

45.

Bouheraoua N, Bonnet C, Labbé A, Sandali O, Lecuen N, Ameline B, Borderie V, Laroche L (2015) Iris-fixated phakic intraocular lens implantation to correct myopia and a predictive model of endothelial cell loss. J Cataract Refract Surg 41:2450–2457. https://doi.org/10.1016/j.jcrs.2015.05.030 CrossRefPubMed

46.

Shajari M, Scheffel M, Koss MJ, Kohnen T (2016) Dependency of endothelial cell loss on anterior chamber depth within first 4 years after implantation of iris-supported phakic intraocular lenses to treat high myopia. J Cataract Refract Surg 42:1562–1569. https://doi.org/10.1016/j.jcrs.2016.08.027 CrossRefPubMed

47.

Menezo JL, Cisneros AL, Rodriguez-Salvador V (1998) Endothelial study of iris-claw phakic lens: four year follow-up. J Cataract Refract Surg 24:1039–1049CrossRef

48.

Doors M, Berendschot TT, Webers CA, Nuijts RM (2010) Model to predict endothelial cell loss after iris-claw phakic intraocular lens implantation. Invest Ophthalmol Vis Sci 51:811–815. https://doi.org/10.1167/iovs.09-3981 CrossRefPubMed

49.

MacRae S, Holladay JT, Hilmantel G, Calogero D, Masket S, Stark W, Glasser A, Rorer E, Tarver ME, Nguyen T, Eydelman M (2017) Special report: American Academy of Ophthalmology Task Force Recommendations for specular microscopy for phakic intraocular lenses. Ophthalmology 124:141–142. https://doi.org/10.1016/j.ophtha.2016.09.034 CrossRefPubMed

50.

Bernard P, Fournier M (2006) Definitive stop of marketing, product recall and follow-up of implanted patients. Presbyopia intraocular lenses NEWLIFE/VIVARTE PRESBYOPIC. Agence Française de Sécurité Sanitaire des Produits de Santé (AFSSAPS), V8. 21/12/06. Available in; https://ansm.sante.fr/content/download/14109/169659/version/1/file/dm070101.pdf.

51.

Titiyal JS, Sharma N, Mannan R, Pruthi A, Vajpayee RB (2012) Iris-fixated intraocular lens implantation to correct moderate to high myopia in Asian-Indian eyes: five-year results. J Cataract Refract Surg 38:1446–1452. https://doi.org/10.1016/j.jcrs.2012.03.029 CrossRefPubMed

52.

Yuan X, Ping HZ, Hong WC, Yin D, Ting Z (2012) Five-year follow-up after anterior iris-claw intraocular lens implantation in phakic eyes to correct high myopia. Eye (Lond) 26:321–326. https://doi.org/10.1038/eye.2011.292 CrossRef

53.

Wilson SE (1989) The correction of myopia by lens implantation into phakic eyes. Am J Ophthalmol 108:465–466CrossRef

54.

Fechner PU (1990) Intraocular lenses for the correction of myopia in phakic eyes: short-term success and long-term caution. Refract Corneal Surg 6:242–244PubMed

55.

Fechner PU, van der Heijde GL, Worst JG (1989) The correction of myopia by lens implantation into phakic eyes. Am J Ophthalmol 107:659–663CrossRef

56.

Fechner PU, Strobel J, Wichmann W (1991) Correction of myopia by implantation of a concave Worst-iris claw lens into phakic eyes. Refract Corneal Surg 7:286–298PubMed

57.

Fechner PU (2010) Late loss of corneal endothelial density with refractive iris-claw IOLs. J Cataract Refract Surg 36:352–353. https://doi.org/10.1016/j.jcrs.2009.09.020 CrossRefPubMed

58.

Fechner PU (2010) The status of follow-up treatment for patients with refractive anterior chamber IOLs in phakic eyes. Klin Monatsbl Augenheilkd 227:228. https://doi.org/10.1055/s-0028-1110012 CrossRefPubMed

59.

Budo C (2010) Another view of iris-claw IOL implantation. J Cataract Refract Surg 36:1801–1802; author reply 1802. https://doi.org/10.1016/j.jcrs.2010.07.008 CrossRefPubMed

60.

Culbertson WW, Tseng SC (1994) Corneal disorders in floppy eyelid syndrome. Cornea 13:33–42CrossRef

61.

Galvis V, Tello A, Delgado J, Gutiérrez AJ, Rodríguez L, Chaparro T (2011) Reproducibility of the results of the endothelial analysis with the Topcon sp-3000p® non-contact specular microscope. Rev Sociedad Colombiana de Oftalmología 44:253–260

62.

Liang GL, Wu J, Shi JT, Liu J, He FY, Xu W (2014) Implantable collamer lens versus iris-fixed phakic intraocular lens implantation to correct myopia: a meta-analysis. PLoS One 9:e104649. https://doi.org/10.1371/journal.pone.0104649 CrossRefPubMedPubMedCentral

63.

Módis L Jr, Langenbucher A, Seitz B (2002) Corneal endothelial cell density and pachymetry measured by contact and noncontact specular microscopy. J Cataract Refract Surg 28:1763–1769CrossRef

64.

Galvis V, Tello A, Gutierrez ÁJ (2013) Human corneal endothelium regeneration: effect of ROCK inhibitor. Invest Ophthalmol Vis Sci 54:4971–4973. https://doi.org/10.1167/iovs.13-12388 CrossRefPubMed

Title: Long-term endothelial cell loss with the iris-claw intraocular phakic lenses (Artisan®)
Authors: Virgilio Galvis
John F. Villamil
María Fernanda Acuña
Paul A. Camacho
Jesús Merayo-Lloves
Alejandro Tello
Sandra Lizeth Zambrano
Juan José Rey
Juan Vicente Espinoza
Angélica María Prada
Publication date: 01-12-2019
Publisher: Springer Berlin Heidelberg
Keyword: Cataract
Published in: Graefe's Archive for Clinical and Experimental Ophthalmology / Issue 12/2019
Print ISSN: 0721-832X
Electronic ISSN: 1435-702X
DOI: https://doi.org/10.1007/s00417-019-04506-9

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Long-term endothelial cell loss with the iris-claw intraocular phakic lenses (Artisan®)

Abstract

Purpose

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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