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Published in: Skeletal Radiology 2/2024

11-07-2023 | Carpal Tunnel Syndrome | Scientific Article

Identifying anatomic landmarks and median nerve characteristics for the analysis of persistent carpal tunnel syndrome using magnetic resonance imaging (MRI)

Authors: Christopher Warburton, Clementina Cabrera, Olivia Perez, John Capelle, Seth D. Dodds, Jean Jose

Published in: Skeletal Radiology | Issue 2/2024

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Abstract

Objective

Carpal tunnel syndrome (CTS) is the most common nerve entrapment neuropathy in the USA. In this study, we define anatomical landmarks to assess symptomatic and asymptomatic cohorts with persistent CTS using MRI imaging.

Materials and methods

Distal vs proximal incomplete release was determined using the distal most aspect of the hook of hamate and the distal wrist crease. An incomplete release showed the transverse carpal ligament (TCL) intact at either boundary. Twenty-one patients with persistent CTS were analyzed for incomplete release, median nerve enlargement and T2 signal hyperintensity, and flattening ratio using postoperative wrist MRI. These findings were compared to a ten-patient asymptomatic persistent CTS control group. Fisher’s exact and a Student’s two-tailed t-tests were used to determine statistical significance.

Results

In the symptomatic persistent CTS group, 13 (61.9%) incomplete releases were identified, 5 (38.5%) incomplete distally, and 1 (7.7%) incomplete proximally. There was no statistical significance in the rate of incomplete releases when compared to the asymptomatic group (p = 1.00). T2 signal hyperintensity and enlargement at the site of release showed no statistical significance, (p = 0.319 and p = 0.999, respectively). The mean flattening ratio at the site of release in the symptomatic group (2.45 ± 0.7) was statistically significant compared to the asymptomatic group (1.48 ± 0.46), (p = 0.007).

Conclusion

Utilizing the established landmarks, the full length of the TCL can be assessed via MRI. Additionally, evaluation of the median nerve flattening ratio at the level of the incomplete release may be utilized as an aid to the clinical management of persistent CTS.
Literature
1.
go back to reference Hubbard ZS, Law TY, Rosas S, Jernigan SC, Chim H. Economic benefit of carpal tunnel release in the Medicare patient population. Neurosurg Focus. 2018;44(5):E16.CrossRefPubMedPubMedCentral Hubbard ZS, Law TY, Rosas S, Jernigan SC, Chim H. Economic benefit of carpal tunnel release in the Medicare patient population. Neurosurg Focus. 2018;44(5):E16.CrossRefPubMedPubMedCentral
2.
go back to reference Sevy JO, Varacallo M. Carpal tunnel syndrome. Treasure Island (FL): StatPearls; 2022. Sevy JO, Varacallo M. Carpal tunnel syndrome. Treasure Island (FL): StatPearls; 2022.
3.
go back to reference Spielman AF, Sankaranarayanan S, Skowronski P, Lessard AS, Panthaki Z. Recurrent and persistent carpal tunnel syndrome: “Triple-therapy approach.” J Orthop. 2020;22:431–5.CrossRefPubMedPubMedCentral Spielman AF, Sankaranarayanan S, Skowronski P, Lessard AS, Panthaki Z. Recurrent and persistent carpal tunnel syndrome: “Triple-therapy approach.” J Orthop. 2020;22:431–5.CrossRefPubMedPubMedCentral
4.
go back to reference Jimenez DF, Gibbs SR, Clapper AT. Endoscopic treatment of carpal tunnel syndrome: a critical review. J Neurosurg. 1998;88(5):817–26.CrossRefPubMed Jimenez DF, Gibbs SR, Clapper AT. Endoscopic treatment of carpal tunnel syndrome: a critical review. J Neurosurg. 1998;88(5):817–26.CrossRefPubMed
5.
go back to reference Malhotra R, Kiran EK, Dua A, Mallinath SG, Bhan S. Endoscopic versus open carpal tunnel release: a short-term comparative study. Indian J Orthop. 2007;41(1):57–61.CrossRefPubMedPubMedCentral Malhotra R, Kiran EK, Dua A, Mallinath SG, Bhan S. Endoscopic versus open carpal tunnel release: a short-term comparative study. Indian J Orthop. 2007;41(1):57–61.CrossRefPubMedPubMedCentral
6.
go back to reference Karthik K, Nanda R, Stothard J. Recurrent carpal tunnel syndrome–analysis of the impact of patient personality in altering functional outcome following a vascularised hypothenar fat pad flap surgery. J Hand Microsurg. 2012;4(1):1–6.CrossRefPubMed Karthik K, Nanda R, Stothard J. Recurrent carpal tunnel syndrome–analysis of the impact of patient personality in altering functional outcome following a vascularised hypothenar fat pad flap surgery. J Hand Microsurg. 2012;4(1):1–6.CrossRefPubMed
7.
go back to reference Jones NF, Ahn HC, Eo S. Revision surgery for persistent and recurrent carpal tunnel syndrome and for failed carpal tunnel release. Plast Reconstr Surg. 2012;129(3):683–92.CrossRefPubMed Jones NF, Ahn HC, Eo S. Revision surgery for persistent and recurrent carpal tunnel syndrome and for failed carpal tunnel release. Plast Reconstr Surg. 2012;129(3):683–92.CrossRefPubMed
8.
go back to reference Coady-Fariborzian L, McGreane A. Comparison of carpal tunnel release methods and complications. Fed Pract. 2015;32(6):40–4.PubMedPubMedCentral Coady-Fariborzian L, McGreane A. Comparison of carpal tunnel release methods and complications. Fed Pract. 2015;32(6):40–4.PubMedPubMedCentral
9.
go back to reference Gelberman RH, Pfeffer GB, Galbraith RT, Szabo RM, Rydevik B, Dimick M. Results of treatment of severe carpal-tunnel syndrome without internal neurolysis of the median nerve. J Bone Joint Surg Am. 1987;69(6):896–903.CrossRefPubMed Gelberman RH, Pfeffer GB, Galbraith RT, Szabo RM, Rydevik B, Dimick M. Results of treatment of severe carpal-tunnel syndrome without internal neurolysis of the median nerve. J Bone Joint Surg Am. 1987;69(6):896–903.CrossRefPubMed
10.
go back to reference Kulick MI, Gordillo G, Javidi T, Kilgore ES Jr, Newmayer WL 3rd. Long-term analysis of patients having surgical treatment for carpal tunnel syndrome. J Hand Surg Am. 1986;11(1):59–66.CrossRefPubMed Kulick MI, Gordillo G, Javidi T, Kilgore ES Jr, Newmayer WL 3rd. Long-term analysis of patients having surgical treatment for carpal tunnel syndrome. J Hand Surg Am. 1986;11(1):59–66.CrossRefPubMed
11.
go back to reference Chung KC. Operative techniques in hand and wrist surgery. 4th ed. Amsterdam: Elsevier; 2022. Chapter 55, Open carpal tunnel release; p. 426–32. Chung KC. Operative techniques in hand and wrist surgery. 4th ed. Amsterdam: Elsevier; 2022. Chapter 55, Open carpal tunnel release; p. 426–32.
12.
13.
go back to reference Seiler JG 3rd, Daruwalla JH, Payne SH, Faucher GK. Normal palmar anatomy and variations that impact median nerve decompression. J Am Acad Orthop Surg. 2017;25(9):e194–203.CrossRefPubMed Seiler JG 3rd, Daruwalla JH, Payne SH, Faucher GK. Normal palmar anatomy and variations that impact median nerve decompression. J Am Acad Orthop Surg. 2017;25(9):e194–203.CrossRefPubMed
15.
go back to reference Ng AWH, Griffith JF, Ng ISH. MRI of carpal tunnel syndrome: before and after carpal tunnel release. Clin Radiol. 2021;76(12):940 e929-940 e935.CrossRef Ng AWH, Griffith JF, Ng ISH. MRI of carpal tunnel syndrome: before and after carpal tunnel release. Clin Radiol. 2021;76(12):940 e929-940 e935.CrossRef
16.
go back to reference Ghasemi-Rad M, Nosair E, Vegh A, Mohammadi A, Akkad A, Lesha E, et al. A handy review of carpal tunnel syndrome: from anatomy to diagnosis and treatment. World J Radiol. 2014;6(6):284–300.CrossRefPubMedPubMedCentral Ghasemi-Rad M, Nosair E, Vegh A, Mohammadi A, Akkad A, Lesha E, et al. A handy review of carpal tunnel syndrome: from anatomy to diagnosis and treatment. World J Radiol. 2014;6(6):284–300.CrossRefPubMedPubMedCentral
17.
go back to reference Campagna R, Pessis E, Feydy A, Guerini H, Le Viet D, Corlobe P, et al. MRI assessment of recurrent carpal tunnel syndrome after open surgical release of the median nerve. AJR Am J Roentgenol. 2009;193(3):644–50.CrossRefPubMed Campagna R, Pessis E, Feydy A, Guerini H, Le Viet D, Corlobe P, et al. MRI assessment of recurrent carpal tunnel syndrome after open surgical release of the median nerve. AJR Am J Roentgenol. 2009;193(3):644–50.CrossRefPubMed
18.
go back to reference Uchiyama S, Itsubo T, Yasutomi T, Nakagawa H, Kamimura M, Kato H. Quantitative MRI of the wrist and nerve conduction studies in patients with idiopathic carpal tunnel syndrome. J Neurol Neurosurg Psychiatry. 2005;76(8):1103–8.CrossRefPubMedPubMedCentral Uchiyama S, Itsubo T, Yasutomi T, Nakagawa H, Kamimura M, Kato H. Quantitative MRI of the wrist and nerve conduction studies in patients with idiopathic carpal tunnel syndrome. J Neurol Neurosurg Psychiatry. 2005;76(8):1103–8.CrossRefPubMedPubMedCentral
19.
go back to reference Yao L, Gai N. Median nerve cross-sectional area and MRI diffusion characteristics: normative values at the carpal tunnel. Skeletal Radiol. 2009;38(4):355–61.CrossRefPubMed Yao L, Gai N. Median nerve cross-sectional area and MRI diffusion characteristics: normative values at the carpal tunnel. Skeletal Radiol. 2009;38(4):355–61.CrossRefPubMed
20.
go back to reference El-Karabaty H, Hetzel A, Galla TJ, Horch RE, Lucking CH, Glocker FX. The effect of carpal tunnel release on median nerve flattening and nerve conduction. Electromyogr Clin Neurophysiol. 2005;45(4):223–7.PubMed El-Karabaty H, Hetzel A, Galla TJ, Horch RE, Lucking CH, Glocker FX. The effect of carpal tunnel release on median nerve flattening and nerve conduction. Electromyogr Clin Neurophysiol. 2005;45(4):223–7.PubMed
21.
go back to reference Cudlip SA, Howe FA, Clifton A, Schwartz MS, Bell BA. Magnetic resonance neurography studies of the median nerve before and after carpal tunnel decompression. J Neurosurg. 2002;96(6):1046–51.CrossRefPubMed Cudlip SA, Howe FA, Clifton A, Schwartz MS, Bell BA. Magnetic resonance neurography studies of the median nerve before and after carpal tunnel decompression. J Neurosurg. 2002;96(6):1046–51.CrossRefPubMed
22.
go back to reference MacDonald RI, Lichtman DM, Hanlon JJ, Wilson JN. Complications of surgical release for carpal tunnel syndrome. J Hand Surg Am. 1978;3(1):70–6.CrossRefPubMed MacDonald RI, Lichtman DM, Hanlon JJ, Wilson JN. Complications of surgical release for carpal tunnel syndrome. J Hand Surg Am. 1978;3(1):70–6.CrossRefPubMed
23.
go back to reference Lee DH, Masear VR, Meyer RD, Stevens DM, Colgin S. Endoscopic carpal tunnel release: a cadaveric study. J Hand Surg Am. 1992;17(6):1003–8.CrossRefPubMed Lee DH, Masear VR, Meyer RD, Stevens DM, Colgin S. Endoscopic carpal tunnel release: a cadaveric study. J Hand Surg Am. 1992;17(6):1003–8.CrossRefPubMed
24.
go back to reference Brown MG, Keyser B, Rothenberg ES. Endoscopic carpal tunnel release. J Hand Surg Am. 1992;17(6):1009–11.CrossRefPubMed Brown MG, Keyser B, Rothenberg ES. Endoscopic carpal tunnel release. J Hand Surg Am. 1992;17(6):1009–11.CrossRefPubMed
25.
go back to reference Ng AWH, Griffith JF, Tsai CSC, Tse WL, Mak M, Ho PC. MRI of the carpal tunnel 3 and 12 months after endoscopic carpal tunnel release. AJR Am J Roentgenol. 2021;216(2):464–70.CrossRefPubMed Ng AWH, Griffith JF, Tsai CSC, Tse WL, Mak M, Ho PC. MRI of the carpal tunnel 3 and 12 months after endoscopic carpal tunnel release. AJR Am J Roentgenol. 2021;216(2):464–70.CrossRefPubMed
Metadata
Title
Identifying anatomic landmarks and median nerve characteristics for the analysis of persistent carpal tunnel syndrome using magnetic resonance imaging (MRI)
Authors
Christopher Warburton
Clementina Cabrera
Olivia Perez
John Capelle
Seth D. Dodds
Jean Jose
Publication date
11-07-2023
Publisher
Springer Berlin Heidelberg
Published in
Skeletal Radiology / Issue 2/2024
Print ISSN: 0364-2348
Electronic ISSN: 1432-2161
DOI
https://doi.org/10.1007/s00256-023-04397-2

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