Skip to main content
Top
Published in: Clinical Rheumatology 1/2007

01-01-2007 | Brief Report

Carnitine: a therapeutic option for childhood psoriatic onycho-pachydermo-periostitis (POPP)

Authors: Pieranna Fietta, Paolo Manganelli

Published in: Clinical Rheumatology | Issue 1/2007

Login to get access

Abstract

Psoriatic onycho-pachydermo-periostitis (POPP) is a rare subset of psoriatic arthritis, characterized by onychopathy, painful thickening of the periungual soft tissues, and radiological features consisting of an exuberant periosteal reaction of the terminal phalanx. The POPP treatment is debated, and side effect risk of therapies may not be offset by their benefits. We report on a successful treatment with carnitine in a 15-year old boy suffering from POPP.
Literature
1.
go back to reference Fietta P, Manganelli P (2005) Childhood onset of psoriatic onycho-pachydermo-periostitis (POPP). J Eur Acad Dermatol Venereol 19:780–782PubMedCrossRef Fietta P, Manganelli P (2005) Childhood onset of psoriatic onycho-pachydermo-periostitis (POPP). J Eur Acad Dermatol Venereol 19:780–782PubMedCrossRef
2.
go back to reference Afeltra A, Amoroso A, Sgro P, Gandini L, Lenzi A (2004) Clinical improvement in psoriatic arthritis symptoms during treatment for infertility with carnitine. Clin Exp Rheumatol 22:138PubMed Afeltra A, Amoroso A, Sgro P, Gandini L, Lenzi A (2004) Clinical improvement in psoriatic arthritis symptoms during treatment for infertility with carnitine. Clin Exp Rheumatol 22:138PubMed
3.
go back to reference Fournié B, Viraben R, Durroux R, Lassoued S, Gay R, Fournié A (1989) Psoriatic onycho-pachydermo-periostitis of the big toe. Anatomo-clinical study and physiopathogenic approach apropos of 4 cases. Rev Rhum Mal Osteoartic 56:579–582PubMed Fournié B, Viraben R, Durroux R, Lassoued S, Gay R, Fournié A (1989) Psoriatic onycho-pachydermo-periostitis of the big toe. Anatomo-clinical study and physiopathogenic approach apropos of 4 cases. Rev Rhum Mal Osteoartic 56:579–582PubMed
4.
go back to reference Boisseau-Garsaud AM, Beylot-Barry M, Doutre MS, Beylot C, Baran R (1996) Psoriatic onycho-pachydermo-periostitis. A variant of psoriatic distal interphalangeal arthritis? Arch Dermatol 132:176–180PubMedCrossRef Boisseau-Garsaud AM, Beylot-Barry M, Doutre MS, Beylot C, Baran R (1996) Psoriatic onycho-pachydermo-periostitis. A variant of psoriatic distal interphalangeal arthritis? Arch Dermatol 132:176–180PubMedCrossRef
5.
go back to reference De Pontville M, Dompmartin A, De Raucourt S, Macro M, Remond B, Leroy D (1993) Psoriatic onycho-pachydermo-periostitis. Ann Dermatol Venereol 120:229–232PubMed De Pontville M, Dompmartin A, De Raucourt S, Macro M, Remond B, Leroy D (1993) Psoriatic onycho-pachydermo-periostitis. Ann Dermatol Venereol 120:229–232PubMed
6.
go back to reference Goupille P, Laulan J, Vedérè V, Kaplan G, Valat JP (1995) Psoriatic onycho-periostitis. Scand J Rheumatol 24:53–54PubMed Goupille P, Laulan J, Vedérè V, Kaplan G, Valat JP (1995) Psoriatic onycho-periostitis. Scand J Rheumatol 24:53–54PubMed
7.
go back to reference Bauza A, Redondo P, Aquerreta D (2000) Psoriatic onycho-pachydermo-periostitis: treatment with methotrexate. Br J Dermatol 143:901–902PubMedCrossRef Bauza A, Redondo P, Aquerreta D (2000) Psoriatic onycho-pachydermo-periostitis: treatment with methotrexate. Br J Dermatol 143:901–902PubMedCrossRef
8.
go back to reference Jury CS, Fleming C, Kemmett D (2000) Severe nail dystrophy associated with painful fingertips. Diagnosis: psoriatic onychopachydermoperiostitis (POPP). Arch Dermatol 136:925–930PubMedCrossRef Jury CS, Fleming C, Kemmett D (2000) Severe nail dystrophy associated with painful fingertips. Diagnosis: psoriatic onychopachydermoperiostitis (POPP). Arch Dermatol 136:925–930PubMedCrossRef
9.
go back to reference Dosik JS (2001) Psoriatic onycho-pachydermo-periostitis. Dermatol Online J 7:11PubMed Dosik JS (2001) Psoriatic onycho-pachydermo-periostitis. Dermatol Online J 7:11PubMed
10.
go back to reference Kroiss MM, Vogt T, Finkenzeller T, Landthaler M, Stolz W (2002) Psoriatic onycho-pachydermo-periostitis. Z Rheumatol 61:598–600PubMedCrossRef Kroiss MM, Vogt T, Finkenzeller T, Landthaler M, Stolz W (2002) Psoriatic onycho-pachydermo-periostitis. Z Rheumatol 61:598–600PubMedCrossRef
11.
go back to reference Anders HJ, Sanden S, Kruger K (2002) Psoriatic onycho-pachydermo-periostitis. Z Rheumatol 61:601–604PubMedCrossRef Anders HJ, Sanden S, Kruger K (2002) Psoriatic onycho-pachydermo-periostitis. Z Rheumatol 61:601–604PubMedCrossRef
12.
go back to reference Bongartz T, Härle P, Friedrich S, Karrer S, Vogt T, Seitz A et al (2005) Successful treatment of psoriatic onycho-pachydermo periostitis (POPP) with adalimumab. Arthritis Rheum 52:280–282PubMedCrossRef Bongartz T, Härle P, Friedrich S, Karrer S, Vogt T, Seitz A et al (2005) Successful treatment of psoriatic onycho-pachydermo periostitis (POPP) with adalimumab. Arthritis Rheum 52:280–282PubMedCrossRef
13.
go back to reference Kiziltunc A, Cogalgil S, Cerrahoglu L (1998) Carnitine and antioxidant levels in patients with rheumatoid arthritis. Scand J Rheumatol 27:441–445PubMedCrossRef Kiziltunc A, Cogalgil S, Cerrahoglu L (1998) Carnitine and antioxidant levels in patients with rheumatoid arthritis. Scand J Rheumatol 27:441–445PubMedCrossRef
14.
go back to reference Azzini M, Girelli D, Olivieri O et al (1995) Fatty acids and anti-oxidant micronutrients in psoriatic arthritis. J Rheumatol 22:103–108PubMed Azzini M, Girelli D, Olivieri O et al (1995) Fatty acids and anti-oxidant micronutrients in psoriatic arthritis. J Rheumatol 22:103–108PubMed
Metadata
Title
Carnitine: a therapeutic option for childhood psoriatic onycho-pachydermo-periostitis (POPP)
Authors
Pieranna Fietta
Paolo Manganelli
Publication date
01-01-2007
Publisher
Springer-Verlag
Published in
Clinical Rheumatology / Issue 1/2007
Print ISSN: 0770-3198
Electronic ISSN: 1434-9949
DOI
https://doi.org/10.1007/s10067-006-0322-2

Other articles of this Issue 1/2007

Clinical Rheumatology 1/2007 Go to the issue
Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine