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BMC Oral Health

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Open Access 01-12-2016 | Research article

Cariogenicity features of Streptococcus mutans in presence of rubusoside

Authors: Jinpu Chu, Tieting Zhang, Kexin He

Published in: BMC Oral Health | Issue 1/2016

Abstract

Background

One promising way of reducing caries is by using sucrose substitutes in food. rubusoside is a prototype sweet substance isolated from the leaves of the plant Rubrus suavissimus S. Lee. (Rosaceae), and is rated sweeter than sucrose. The purpose of this study was to investigate the effects of rubusoside on Streptococcus mutans growth, acidogenicity, and adherence to glass in vitro.

Methods

The effects of rubusoside on the growth and glass surface adhering of Streptococcus mutans were investigated by measuring the optical density of the culture at 540 nm with a spectrophotometer. Rubusoside influence on Streptococcus mutans acidogenicity was determined by measuring the pH of the culture. Sucrose, glucose, maltose, fructose and xylitol were designed to compare with rubusoside.

Results

S. mutans growth in the rubusoside-treated group was significantly lower than that in the sucrose, glucose, maltose and fructose groups (p < 0.05) except for xylitol group (p > 0.05). Sucrose-treated S. mutans exhibited the highest adherence to glass, and rubusoside-treated S. mutans exhibited the lowest. S. mutans adherence to a glass surface and acidogenicity with sucrose were significantly reduced by rubusoside.

Conclusions

Rubusoside may have some potential as a non-cariogenic, non-caloric sweetener.

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Title: Cariogenicity features of Streptococcus mutans in presence of rubusoside
Authors: Jinpu Chu
Tieting Zhang
Kexin He
Publication date: 01-12-2016
Publisher: BioMed Central
Published in: BMC Oral Health / Issue 1/2016
Electronic ISSN: 1472-6831
DOI: https://doi.org/10.1186/s12903-016-0212-1

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Cariogenicity features of Streptococcus mutans in presence of rubusoside

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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