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18-03-2024 | Editorial

Caring for frail patients in the ICU: a multidimensional approach

Authors: Maurizio Cecconi, Susannah Leaver, Christian Jung

Published in: Intensive Care Medicine | Issue 4/2024

Excerpt

Frailty is a state of high vulnerability for adverse health outcomes, including disability, dependency, falls, need for long-term care, and mortality. This condition is associated with geriatric symptoms such as sarcopenia, cognitive impairment and dementia. Whilst it is more frequent in older age, it is not synonymous with old age and should, therefore, be considered separately. …

Fried LP, Ferrucci L, Darer J, Williamson JD, Anderson G (2004) Untangling the concepts of disability, frailty, and comorbidity: implications for improved targeting and care. J Gerontol A Biol Sci Med Sci 59:255–263CrossRefPubMed

Rockwood K, Song X, MacKnight C, Bergman H, Hogan DB, McDowell I, Mitnitski A (2005) A global clinical measure of fitness and frailty in elderly people. CMAJ 173:489–495CrossRefPubMedPubMedCentral

Muscedere J, Waters B, Varambally A, Bagshaw SM, Boyd JG, Maslove D, Sibley S, Rockwood K (2017) The impact of frailty on intensive care unit outcomes: a systematic review and meta-analysis. Intensive Care Med 43:1105–1122CrossRefPubMedPubMedCentral

Guidet B, de Lange DW, Boumendil A, Leaver S, Watson X, Boulanger C, Szczeklik W, Artigas A, Morandi A, Andersen F, Zafeiridis T, Jung C, Moreno R, Walther S, Oeyen S, Schefold JC, Cecconi M, Marsh B, Joannidis M, Nalapko Y, Elhadi M, Fjolner J, Flaatten H, Group VIPs (2020) The contribution of frailty, cognition, activity of daily life and comorbidities on outcome in acutely admitted patients over 80 years in European ICUs: the VIP2 study. Intensive Care Med 46:57–69CrossRefPubMed

Ibarz M, Boumendil A, Haas LEM, Irazabal M, Flaatten H, de Lange DW, Morandi A, Andersen FH, Bertolini G, Cecconi M, Christensen S, Faraldi L, Fjolner J, Jung C, Marsh B, Moreno R, Oeyen S, Ohman CA, Bollen Pinto B, Soliman IW, Szczeklik W, Valentin A, Watson X, Zaferidis T, Guidet B, Artigas A, Study VIP (2020) Sepsis at ICU admission does not decrease 30-day survival in very old patients: a post-hoc analysis of the VIP1 multinational cohort study. Ann Intensive Care 10:56CrossRefPubMedPubMedCentral

Jung C, Wernly B, Muessig JM, Kelm M, Boumendil A, Morandi A, Andersen FH, Artigas A, Bertolini G, Cecconi M, Christensen S, Faraldi L, Fjolner J, Lichtenauer M, Bruno RR, Marsh B, Moreno R, Oeyen S, Ohman CA, Pinto BB, Soliman IW, Szczeklik W, Valentin A, Watson X, Zafeiridis T, De Lange DW, Guidet B, Flaatten H (2019) A comparison of very old patients admitted to intensive care unit after acute versus elective surgery or intervention. J Crit Care 52:141–148CrossRefPubMed

Fronczek J, Flaatten H, Guidet B, Polok K, Andersen FH, Andrew BY, Artigas A, Beil M, Cecconi M, Christensen S, de Lange DW, Fjolner J, Gorka J, Joannidis M, Jung C, Kusza K, Leaver S, Marsh B, Morandi A, Moreno R, Oeyen S, Owczuk R, Agvald-Ohman C, Pinto BB, Rhodes A, Schefold JC, Soliman IW, Valentin A, Walther S, Watson X, Zafeiridis T, Szczeklik W, Vip, Group VIPs (2022) Short-term mortality of patients ≥ 80 years old admitted to European intensive care units: an international observational study. Br J Anaesth 129:58–66CrossRefPubMed

Guidet B, Jung C, Flaatten H, Fjolner J, Artigas A, Pinto BB, Schefold JC, Beil M, Sigal S, van Heerden PV, Szczeklik W, Joannidis M, Oeyen S, Kondili E, Marsh B, Andersen FH, Moreno R, Cecconi M, Leaver S, De Lange DW, Boumendil A, Vip, Groups Cs (2022) Increased 30-day mortality in very old ICU patients with COVID-19 compared to patients with respiratory failure without COVID-19. Intensive Care Med 48:435–447CrossRefPubMedPubMedCentral

Jung C, Flaatten H, Fjolner J, Bruno RR, Wernly B, Artigas A, Bollen Pinto B, Schefold JC, Wolff G, Kelm M, Beil M, Sviri S, van Heerden PV, Szczeklik W, Czuczwar M, Elhadi M, Joannidis M, Oeyen S, Zafeiridis T, Marsh B, Andersen FH, Moreno R, Cecconi M, Leaver S, Boumendil A, De Lange DW, Guidet B, Group Cs (2021) The impact of frailty on survival in elderly intensive care patients with COVID-19: the COVIP study. Crit Care 25:149CrossRefPubMedPubMedCentral

10.

Bagshaw M, Majumdar SR, Rolfson DB, Ibrahim Q, McDermid RC, Stelfox HT (2016) A prospective multicenter cohort study of frailty in younger critically ill patients. Crit Care 20:175CrossRefPubMedPubMedCentral

11.

Guidet B, Vallet H, Flaatten H, Joynt G, Bagshaw SM, Leaver SK, Beil M, Du B, Forte DN, Angus DC, Sviri S, de Lange D, Herridge MS, Jung C (2024) The trajectory of very old critically ill patients. Intensive Care Med 50(2):181–194CrossRefPubMed

12.

Bagshaw SM, Stelfox HT, McDermid RC, Rolfson DB, Tsuyuki RT, Baig N, Artiuch B, Ibrahim Q, Stollery DE, Rokosh E, Majumdar SR (2014) Association between frailty and short- and long-term outcomes among critically ill patients: a multicentre prospective cohort study. CMAJ 186:E95-102CrossRefPubMedPubMedCentral

13.

Vink EE, Azoulay E, Caplan A, Kompanje EJO, Bakker J (2018) Time-limited trial of intensive care treatment: an overview of current literature. Intensive Care Med 44:1369–1377CrossRefPubMed

14.

Kim SW, Han HS, Jung HW, Kim KI, Hwang DW, Kang SB, Kim CH (2014) Multidimensional frailty score for the prediction of postoperative mortality risk. JAMA Surg 149:633–640CrossRefPubMed

15.

Guidet B, Jung C, Flaatten H, Fjolner J, Artigas A, Pinto BB, Schefold JC, Beil M, Sigal S, van Heerden PV, Szczeklik W, Joannidis M, Oeyen S, Kondili E, Marsh B, Andersen FH, Moreno R, Cecconi M, Leaver S, De Lange DW, Boumendil A, Vip, groups Cs (2022) Correction to: Increased 30-day mortality in very old ICU patients with COVID-19 compared to patients with respiratory failure without COVID-19. Intensive Care Med 48:797–799CrossRefPubMedPubMedCentral

Title: Caring for frail patients in the ICU: a multidimensional approach
Authors: Maurizio Cecconi
Susannah Leaver
Christian Jung
Publication date: 18-03-2024
Publisher: Springer Berlin Heidelberg
Published in: Intensive Care Medicine / Issue 4/2024
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-024-07364-0

2024 ASCO Annual Meeting

Springer Medicine

Caring for frail patients in the ICU: a multidimensional approach

Excerpt

2024 ASCO Annual Meeting

Springer Medicine

Excerpt

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