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BMC Medical Informatics and Decision Making

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Open Access 01-12-2019 | Care | Research article

Patient centred variables with univariate associations with unplanned ICU admission: a systematic review

Authors: James Malycha, Timothy Bonnici, David A. Clifton, Guy Ludbrook, J. Duncan Young, Peter J. Watkinson

Published in: BMC Medical Informatics and Decision Making | Issue 1/2019

Abstract

Background

Multiple predictive scores using Electronic Patient Record data have been developed for hospitalised patients at risk of clinical deterioration. Methods used to select patient centred variables for inclusion in these scores varies. We performed a systematic review to describe univariate associations with unplanned Intensive Care Unit (ICU) admission with the aim of assisting model development for future scores that predict clinical deterioration.

Methods

Data sources were MEDLINE, EMBASE, CINAHL, CENTRAL and the Cochrane Database of Systematic Reviews. Included studies were published since 2000 describing an association between patient centred variables and unplanned ICU admission determined using univariate analysis. Two authors independently screened titles, abstracts and full texts against inclusion and exclusion criteria. DistillerSR (Evidence Partners, Canada, Ottawa, Ontario) software was used to manage the data and identify duplicate search results. All screening and data extraction forms were implemented within DistillerSR. Study quality was assessed using an adapted version of the Newcastle-Ottawa Scale. Variables were analysed for strength of association with unplanned ICU admission.

Results

The database search yielded 1520 unique studies; 1462 were removed after title and abstract review; 57 underwent full text screening; 16 studies were included. One hundred and eighty nine variables with an evaluated univariate association with unplanned ICU admission were described.

Discussion

Being male, increasing age, a history of congestive cardiac failure or diabetes, a diagnosis of hepatic disease or having abnormal vital signs were all strongly associated with ICU admission.

Conclusion

These findings will assist variable selection during the development of future models predicting unplanned ICU admission.

Trial registration

This study is a component of a larger body of work registered in the ISRCTN registry (ISRCTN12518261).

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Title: Patient centred variables with univariate associations with unplanned ICU admission: a systematic review
Authors: James Malycha
Timothy Bonnici
David A. Clifton
Guy Ludbrook
J. Duncan Young
Peter J. Watkinson
Publication date: 01-12-2019
Publisher: BioMed Central
Keyword: Care
Published in: BMC Medical Informatics and Decision Making / Issue 1/2019
Electronic ISSN: 1472-6947
DOI: https://doi.org/10.1186/s12911-019-0820-1

At a glance: The STEP trials

Springer Medicine

Patient centred variables with univariate associations with unplanned ICU admission: a systematic review

Abstract

Background

Methods

Results

Discussion

Conclusion

Trial registration

At a glance: The STEP trials

Springer Medicine

Abstract

Background

Methods

Results

Discussion

Conclusion

Trial registration

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