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Health and Quality of Life Outcomes
Published in: Health and Quality of Life Outcomes 1/2020

01-12-2020 | Care | Research

Unmet supportive care needs and its relation to quality of life among adult acute leukaemia patients in China: a cross-sectional study

Authors: Yan Jie, Ying Wang, Jingyi Chen, Chunfeng Wang, Yingchun Lin, Rong Hu, Yong Wu

Published in: Health and Quality of Life Outcomes | Issue 1/2020

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Abstract

Background

Patients with acute leukaemia (AL) usually require prolonged periods of hospitalisation. The treatment and clinical symptoms may lead to patients’ supportive care needs (SCNs) not being met and impairs their quality of life (QoL). Studies on QoL and SCNs among AL patients are limited. This study aimed to identify the unmet SCNs and its relation to QoL of adult AL patients in China.

Methods

This multicentre cross-sectional study recruited 346 participants to complete a self-developed questionnaire, detailing demographic information and disease-related variables. A 34-item Supportive Care Needs Survey (SCNS-SF34) was used to identify unmet SCNs, and the Functional Assessment of Cancer Therapy-Leukaemia (FACT-Leu) questionnaire measured patients’ QoL.

Results

Unmet SCN rates for the 34 items ranged from17.6 to 81.7%. Patients’ needs were high for health systems and information, but low in the sexual domain. The results reveal nine factors associated with the unmet SCNs of adult AL patients, including marital status, original residence, age, education, occupation, other diseases, chemotherapy course, disease course, and treatment stage (p < 0.05). The total score of the FACT-Leu negatively correlated with the SCNS-SF34 in the physical/daily living (r = − 0.527, p < 0.01), psychological (r = − 0.688, p < 0.01), sexual (r = − 0.170, p < 0.01), patient care and support (r = − 0.352, p < 0.01), and health systems and information (r = − 0.220, p < 0.01) domains.

Conclusions

Adult AL patients exhibit a high demand for unmet SCNs, especially in the domain of health systems and information. There was a significant association between patients’ unmet SCNs and QoL. Future research should develop tailored interventions to address the unmet SCNs of adult AL patients, to further improve their QoL.
Appendix
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Literature
1.
Miranda-Filho A, Piñeros M, Ferlay J, Soerjomataram I, Monnereau A, Bray F. Epidemiological patterns of leukaemia in 184 countries: a population-based study. Lancet Haematol. 2018;5:e14–24.PubMedCrossRef
2.
Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68:394–424.PubMed
3.
Chen W, Zheng R, Baade PD, Zhang S, Zeng H, Bray F, et al. Cancer statistics in China, 2015. CA Cancer J Clin. 2016;66:115–32.CrossRefPubMed
4.
5.
Albrecht TA. Physiologic and psychological symptoms experienced by adults with acute leukemia: an integrative literature review. Oncol Nurs Forum. 2014;41:286–95.PubMedPubMedCentralCrossRef
6.
Leak Bryant A, Walton AL, Pergolotti M, Phillips B, Bailey C, Mayer DK, et al. Perceived benefits and barriers to exercise for recently treated adults with acute leukemia. Oncol Nurs Forum. 2017;44:413–20.PubMedCrossRef
7.
Cameron K. Review:chemotherapy plus supportive care improves survival and quality of life in advanced or metastatic gastrointestinal cancer more than supportive care alone. Evid Based Nurs. 2005;8:18.PubMedCrossRef
8.
Albrecht TA, Boyiadzis M, Elswick RK Jr, Starkweather A, Rosenzweig M. Symptom management and psychosocial needs of adults with acute myeloid leukemia during induction treatment: a pilot study. Cancer Nurs. 2017;40:E31–8.PubMedPubMedCentralCrossRef
9.
Leak Bryant A, Lee Walton A, Shaw-Kokot J, Mayer DK, Reeve BB. Patient-reported symptoms and quality of life in adults with acute leukemia: a systematic review. Oncol Nurs Forum. 2015;42:E91–E101.PubMedCrossRef
10.
Jarrett N, Scott I, Addington-Hall J, Amir Z, Brearley S, Hodges L, et al. Informing future research priorities into the psychological and social problems faced by cancer survivors: a rapid review and synthesis of the literature. Eur J Oncol Nurs. 2013;17:510–20.PubMedCrossRef
11.
Stein KD, Syrjala KL, Andrykowski MA. Physical and psychological long-term and late effects of cancer. Cancer. 2008;112:2577–92.PubMedCrossRef
12.
13.
Yu FF, Bai YN, He H, Zhu L, Zhang RL, Jiao HX, et al. Identifying the unmet supportive care needs, with concomitant influencing factors, in adult acute leukemia patients in China. Eur J Oncol Nurs. 2017;30:67–74.PubMedCrossRef
14.
Lam WWT, Tsang J, Yeo W, Suen J, Ho WM, Yau TK, et al. The evolution of supportive care needs trajectories in women with advanced breast cancer during the 12 months following diagnosis. Support Care Cancer. 2013;22:635–44.PubMedCrossRef
15.
Chen SC, Chiou SC, Yu CJ, Lee YH, Liao WY, Hsieh PY, et al. The unmet supportive care needs-what advanced lung cancer patients' caregivers need and related factors. Support Care Cancer. 2016;24:2999–3009.PubMedCrossRef
16.
Umezawa S, Fujisawa D, Fujimori M, Ogawa A, Matsushima E, Miyashita M. Prevalence, associated factors and source of support concerning supportive care needs among Japanese cancer survivors. Psycho-Oncology. 2015;24:635–42.PubMedCrossRef
17.
Richardson A. Improving supportive and palliative care for adults with cancer. Nurs Times. 2003;99:49.PubMed
18.
So WK, Chow KM, Chan HY, Choi KC, Wan RW, Mak SS, et al. Quality of life and most prevalent unmet needs of Chinese breast cancer survivors at one year after cancer treatment. Eur J Oncol Nurs. 2014;18:323–8.PubMedCrossRef
19.
Galvão DA, Newton RU, Gardiner RA, Girgis A, Lepore SJ, Stiller A, et al. Compliance to exercise-oncology guidelines in prostate cancer survivors and associations with psychological distress, unmet supportive care needs, and quality of life. Psycho-Oncology. 2015;24(10):1241-9.
20.
Wang C, Yan J, Chen J, Wang Y, Lin YC, Hu R, et al. Factors associated with quality of life of adult patients with acute leukemia and their family caregivers in China: a cross-sectional study. Health Qual Life Outcomes. 2020;18:8.PubMedPubMedCentralCrossRef
21.
Cramarossa G, Chow E, Zhang L, Bedard G, Zeng L, Sahgal A, et al. Predictive factors for overall quality of life in patients with advanced cancer. Support Care Cancer. 2013;21:1709–16.PubMedCrossRef
22.
Simon AE, Thompson MR, Flashman K, Wardle J. Disease stage and psychosocial outcomes in colorectal cancer. Colorectal Dis. 2009;11:19–25.PubMedCrossRef
23.
Siddiqi A, Given CW, Given B, Sikorskii A. Quality of life among patients with primary, metastatic and recurrent cancer. Eur J Cancer Care (Engl). 2009;18:84–96.CrossRef
24.
Doubova SV, Casales-Hernandez MG, Perez-Cuevas R. Supportive care needs and association with quality of life of Mexican adults with solid cancers. Cancer Nurs. 2018;41:E1–E12.PubMedCrossRef
25.
Galvao DA, Newton RU, Gardiner RA, Girgis A, Lepore SJ, Stiller A, et al. Compliance to exercise-oncology guidelines in prostate cancer survivors and associations with psychological distress, unmet supportive care needs, and quality of life. Psychooncology. 2015;24:1241–9.PubMedCrossRef
26.
Jordan K, Aapro M, Kaasa S, Ripamonti CI, Scotte F, Strasser F, et al. European Society for Medical Oncology (ESMO) position paper on supportive and palliative care. Ann Oncol. 2018;29:36–43.PubMedCrossRef
27.
Smith AB, King M, Butow P, Luckett T, Grimison P, Toner GC, et al. The prevalence and correlates of supportive care needs in testicular cancer survivors: a cross-sectional study. Psychooncology. 2013;22:2557–64.PubMedCrossRef
28.
Lam WW, Au AH, Wong JH, Lehmann C, Koch U, Fielding R, et al. Unmet supportive care needs: a cross-cultural comparison between Hong Kong Chinese and German Caucasian women with breast cancer. Breast Cancer Res Treat. 2011;130:531–41.PubMedCrossRef
29.
Cossich T, Schofield P, McLachlan SA. Validation of the cancer needs questionnaire (CNQ) short-form version in an ambulatory cancer setting. Qual Life Res. 2004;13:1225–33.PubMedCrossRef
30.
ML W. Statistical analysis of questionnaires: SPSS operation and application. Chongqing: Chongqing University Press; 2010.
31.
Fayers PM. MD: quality of life: assessment, analysis and interpretation. Chichester: Wiley; 2000.CrossRef
32.
Kerr LM, Harrison MB, Medves J, Tranmer J. Supportive care needs of parents of children with cancer: transition from diagnosis to treatment. Oncol Nurs Forum. 2004;31:E116–26.PubMedCrossRef
33.
34.
Boyes A, Girgis A, Lecathelinais C. Brief assessment of adult cancer patients' perceived needs: development and validation of the 34-item supportive care needs survey (SCNS-SF34). J Eval Clin Pract. 2009;15:602–6.PubMedCrossRef
35.
Au A, Lam W, Tsang J, Yau TK, Soong I, Yeo W, et al. Supportive care needs in Hong Kong Chinese women confronting advanced breast cancer. Psychooncology. 2013;22:1144–51.PubMedCrossRef
36.
Meng Q, Yang Z, Wu Y, Xiao Y, Gu X, Zhang M, et al. Reliability analysis of the Chinese version of the functional assessment of cancer therapy - leukemia (FACT-Leu) scale based on multivariate generalizability theory. Health Qual Life Outcomes. 2017;15:93.PubMedPubMedCentralCrossRef
37.
Cheng KKF, Wong WH, Koh C. Unmet needs mediate the relationship between symptoms and quality of life in breast cancer survivors. Support Care Cancer. 2016;24:2025–33.PubMedCrossRef
38.
Armes J, Crowe M, Colbourne L, Morgan H, Murrells T, Oakley C, et al. Patients' supportive care needs beyond the end of cancer treatment: a prospective, longitudinal survey. J Clin Oncol. 2009;27:6172–9.PubMedCrossRef
39.
Rutten LJ, Arora NK, Bakos AD, Aziz N, Rowland J. Information needs and sources of information among cancer patients: a systematic review of research (1980-2003). Patient Educ Couns. 2005;57:250–61.PubMedCrossRef
40.
Schmid-Buchi S, Halfens RJ, Muller M, Dassen T, van den Borne B. Factors associated with supportive care needs of patients under treatment for breast cancer. Eur J Oncol Nurs. 2013;17:22–9.PubMedCrossRef
41.
Williams LAGA, Ahaneku HO, Cortes JE, Garciamanero G, Kantarjian HM, Mendoza TR, et al. A patient-reported outcome measure for symptoms and symptom burden of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). Blood. 2015;126:2094.CrossRef
42.
43.
Voogt E, van der Heide A, van Leeuwen AF, Visser AP, Cleiren MP, Passchier J, et al. Positive and negative affect after diagnosis of advanced cancer. Psychooncology. 2005;14:262–73.PubMedCrossRef
44.
Ream E, Quennell A, Fincham L, Faithfull S, Khoo V, Wilson-Barnett J, et al. Supportive care needs of men living with prostate cancer in England: a survey. Br J Cancer. 2008;98:1903–9.PubMedPubMedCentralCrossRef
45.
Li Q, Lin Y, Zhou H, Xu Y, Xu Y. Supportive care needs and associated factors among Chinese cancer survivors: a cross-sectional study. Support Care Cancer. 2019;27:287–95.PubMedCrossRef
46.
Sanson-Fisher RGA, Boyes A, Bonevski B, Burton L, Cook P. The unmet supportive care needs of patients with cancer. Supportive care review group. Cancer. 2015;88:226–37.CrossRef
47.
Beesley VWL, Rourke P, Janda M, Goldstein D, Gooden H, Merrett N, et al. Risk factors for current and future unmet supportive care needs of people with pancreatic cancer. A longitudinal study. Support Care Cancer. 2016;24:3589–99.PubMedCrossRef
48.
Chen SC, Lai YH, Liao CT, Chang JT, Lin CY, Fan KH, et al. Supportive care needs in newly diagnosed oral cavity cancer patients receiving radiation therapy. Psychooncology. 2013;22:1220–8.PubMedCrossRef
49.
So WK, Chan CW, Choi KC, Wan RW, Mak SS, Chair SY. Perceived unmet needs and health-related quality of life of Chinese cancer survivors at 1 year after treatment. Cancer Nurs. 2013;36:E23–32.PubMedCrossRef
50.
Piazza MF, Galletta M, Portoghese I, Pilia I, Ionta MT, Contu P, et al. Meeting psychosocial and health information needs to ensure quality of cancer care in outpatients. Eur J Oncol Nurs. 2017;29:98–105.PubMedCrossRef
51.
Akechi T, Okuyama T, Endo C, Sagawa R, Uchida M, Nakaguchi T, et al. Patient's perceived need and psychological distress and/or quality of life in ambulatory breast cancer patients in Japan. Psychooncology. 2011;20:497–505.PubMedCrossRef
52.
Oh J, Kim SH, Kim JA. Unmet supportive care needs mediate the relationship betweenfunctional status and quality of life in patients with amyotrophic lateral sclerosis. Palliat Support Care. 2019;17(6):650-4.
53.
Holm LV, Hansen DG, Larsen PV, Johansen C, Vedsted P, Bergholdt SH, et al. Social inequality in cancer rehabilitation: a population-based cohort study. Acta Oncol. 2013;52:410–22.PubMedCrossRef
54.
Snyder CFBA, Brahmer JR, Carducci MA, Pili R, Stearns V, Wolff AC, et al. Needs assessments can identify scores on HRQOL questionnaires that represent problems for patients_ an illustration with the supportive care needs survey and the QLQ-C30. Qual Life Res. 2010;19:837–45.PubMedPubMedCentralCrossRef
Metadata
Title
Unmet supportive care needs and its relation to quality of life among adult acute leukaemia patients in China: a cross-sectional study
Authors
Yan Jie
Ying Wang
Jingyi Chen
Chunfeng Wang
Yingchun Lin
Rong Hu
Yong Wu
Publication date
01-12-2020
Publisher
BioMed Central
Published in
Health and Quality of Life Outcomes / Issue 1/2020
Electronic ISSN: 1477-7525
DOI
https://doi.org/10.1186/s12955-020-01454-5

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