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01-10-2021 | Care | Editorial

Preempting critical care services for patients with hematological malignancies

Authors: Élie Azoulay, Marcio Soares, Étienne Lengliné

Published in: Intensive Care Medicine | Issue 10/2021

Excerpt

An increasing number of critically ill patients is immunocompromised [1, 2], and half of them are treated for hematological malignancies [3]. In hematology patients, admission in an intensive care unit (ICU) might be required at different time points throughout the disease trajectory: organ infiltration and compression by aggressive or bulky malignancies [4], tumor lysis syndrome and metabolic complications of diseases with high tumoral burden [5], bacterial or non-bacterial infections [6], drugs, chimeric antigen receptor T cells (CAR-T) therapy or stem cell transplantation-related toxicity, disease progression, as well as decompensation of associated comorbidities [7]. Even though mortality rate of critically ill patients with hematological malignancies is twice as high compared to non-immunocompromised patients [7, 8], critical care services are used as a bridge to cure. For instance, in ICU survivors, response to chemotherapy, remission, quality of life and 1-year survival, are substantial, and not significantly lower than those in patients who did not require ICU admission [7, 9‐13]. …

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Title: Preempting critical care services for patients with hematological malignancies
Authors: Élie Azoulay
Marcio Soares
Étienne Lengliné
Publication date: 01-10-2021
Publisher: Springer Berlin Heidelberg
Keywords: Care
Hematology
Published in: Intensive Care Medicine / Issue 10/2021
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-021-06521-z

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