Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on medication adherence

LIVE: Thursday 27th June 2024, 18:00-19:30 (CEST)
Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
ADVANCED SEARCH
Log in
Top
Supportive Care in Cancer
Published in: Supportive Care in Cancer 9/2019

01-09-2019 | Care | Review Article

End-of-life care preferences for people with advanced cancer and their families in intensive care units: a systematic review

Authors: Hanan M. Alyami, Raymond Javan Chan, Karen New

Published in: Supportive Care in Cancer | Issue 9/2019

Login to get access

Abstract

Background

Advanced cancer patients’ end-of-life care preferences in oncology units, medical-surgical units, nursing homes and palliative care services have been established. However, less is known about end-of-life care preferences of patients with advanced cancer in intensive care units and their families.

Aim

To explore end-of-life care preferences of patients with advanced cancer and their families in intensive care units and if these align with essential elements for end-of-life care.

Design

Electronic databases were searched up to February 2018. Reference lists of retrieved articles were screened for potential studies.

Results

A total of 112 full text articles were retrieved. Of these, 12 articles reporting outcomes from 10 studies were eligible for inclusion. The majority were retrospective chart reviews (n = 7) and conducted in developed countries (n = 9). Care preferences change over time with deteriorating physical condition. Ongoing patient-centred communication and shared decision-making are critical as is teamwork and involvement of a palliative care team. Marital status, gender and ethnicity appear to influence care preferences. Of those studies examining patient preferences and/or the receiving of their preferences, these could be aligned with approximately half of the Australian essential elements for end-of-life care.

Conclusions

Providing end-of-life care for patients with advanced cancer in intensive care units is challenging. No studies have investigated prospectively the end-of-life care preferences of patients and their families in this acute setting. Further research is required to determine the elements of care preferences for patients with advanced cancer and their families in intensive care units in developing countries.
Appendix
Available only for authorised users
Literature
1.
Sharma N, Sharma AM, Wojtowycz MA, Wang D, Gajra A (2016) Utilization of palliative care and acute care services in older adults with advanced cancer. J Geriatr Oncol 7(1):39–46CrossRefPubMed
2.
Jang RW, Krzyzanowska MK, Zimmermann C, Taback N, Alibhai SM (2015) Palliative care and the aggressiveness of end-of-life care in patients with advanced pancreatic cancer. J Natl Cancer Inst 107(3)
3.
Kim YJ, Kim MJ, Cho YJ, Park JS, Kim JW, Chang H, Lee JO, Lee KW, Kim JH, Yoon HI, Bang SM, Lee JH, Lee CT, Lee JS (2014) Who should be admitted to the intensive care unit? The outcome of intensive care unit admission in stage IIIB-IV lung cancer patients. Med Oncol 31(3):847CrossRefPubMed
4.
5.
Tosi P, Barosi G, Lazzaro C, Liso V, Marchetti M, Morra E, Pession A, Rosti G, Santoro A, Zinzani PL, Tura S (2008) Consensus conference on the management of tumor lysis syndrome. Haematologica. 93(12):1877–1885CrossRefPubMed
6.
Greer JA, Pirl WF, Jackson VA, Muzikansky A, Lennes IT, Heist RS, Gallagher ER, Temel JS (2012) Effect of early palliative care on chemotherapy use and end-of-life care in patients with metastatic non–small-cell lung cancer. J Clin Oncol 30(4):394–400CrossRefPubMed
7.
8.
Australian Commission on Safety and Quality in Health Care (2015) National Consensus Statement: essential elements for safe and high-quality end-of-life care. ACSQHC, Sydney
9.
Canadian Nurses Association.2018 The palliative approach to care and the role of the nurse. Ottawa
10.
The National Institute for health and care excellence. 2015 Care of dying adults in the last days of life.
11.
Kwak J, Haley WE, Chiriboga DA (2008) Racial differences in hospice use and in-hospital death among Medicare and Medicaid dual-eligible nursing home residents. Gerontologist. 48(1):32–41CrossRefPubMed
12.
Levy C, Hutt E, Pointer L (2012) Site of death among veterans living in veterans affairs nursing homes. J Am Med Dir Assoc 13(3):199–201CrossRefPubMed
13.
Ng CW, Cheong SK, Govinda Raj A, Teo W, Leong I (2016) End-of-life care preferences of nursing home residents: results of a cross-sectional study. Palliat Med 30(9):843–853CrossRefPubMed
14.
Shin JA, Parkes A, El-Jawahri A, Traeger L, Knight H, Gallagher ER et al (2016) Retrospective evaluation of palliative care and hospice utilization in hospitalized patients with metastatic breast cancer. Palliat Med 30(9):854–861CrossRefPubMedPubMedCentral
15.
Moher D, Liberati A, Tetzlaff J, Altman DG, Group P (2009) Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med 6(7):e1000097CrossRefPubMedPubMedCentral
16.
17.
18.
Truog RD, Campbell ML, Curtis JR, Haas CE, Luce JM, Rubenfeld GD, Rushton CH, Kaufman DC, American Academy of Critical Care Medicine (2008) Recommendations for end-of-life care in the intensive care unit: a consensus statement by the American College [corrected] of Critical Care Medicine. Crit Care Med 36(3):953–963CrossRefPubMed
19.
Romano AM, Gade KE, Nielsen G, Havard R, Harrison JH, Barclay J et al (2017) Early palliative care reduces end-of-life intensive care unit (ICU) use but not ICU course in patients with advanced cancer. Oncologist. 22(3):318–323CrossRefPubMedPubMedCentral
20.
Cruz VM, Camalionte L, Caruso P (2015) Factors associated with futile end-of-life intensive care in a cancer hospital. Am J Hosp Palliat Care 32(3):329–334CrossRefPubMed
21.
Miller SJ, Desai N, Pattison N, Droney JM, King A, Farquhar-Smith P, Gruber PC (2015) Quality of transition to end-of-life care for cancer patients in the intensive care unit. Ann Intensive Care 5(1):59CrossRefPubMed
22.
Blechman JA, Rizk N, Stevens MM, Periyakoil VS (2013) Unmet quality indicators for metastatic cancer patients admitted to intensive care unit in the last two weeks of life. J Palliat Med 16(10):1285–1289CrossRefPubMedPubMedCentral
23.
Fu S, Hong DS, Naing A, Wheler J, Falchook G, Wen S, Howard A, Barber D, Nates J, Price K, Kurzrock R (2011) Outcome analyses after the first admission to an intensive care unit in patients with advanced cancer referred to a phase I clinical trials program. J Clin Oncol 29(26):3547–3552CrossRefPubMed
24.
Cesta MA, Cardenas-Turanzas M, Wakefield C, Price KJ, Nates JL (2009) Life-supportive therapy withdrawal and length of stay in a large oncologic intensive care unit at the end of life. J Palliat Med 12(8):713–718CrossRefPubMed
25.
Delgado-Guay MO, Parsons HA, Li Z, Palmer LJ, Bruera E (2009) Symptom distress, interventions, and outcomes of intensive care unit cancer patients referred to a palliative care consult team. Cancer. 115(2):437–445CrossRefPubMed
26.
Balboni TA, Balboni M, Enzinger AC, Gallivan K, Paulk ME, Wright A, Steinhauser K, VanderWeele TJ, Prigerson HG (2013) Provision of spiritual support to patients with advanced cancer by religious communities and associations with medical care at the end of life. JAMA Intern Med 173(12):1109–1117CrossRefPubMedPubMedCentral
27.
Loggers ET, Maciejewski PK, Paulk E, DeSanto-Madeya S, Nilsson M, Viswanath K, Wright AA, Balboni TA, Temel J, Stieglitz H, Block S, Prigerson HG (2009) Racial differences in predictors of intensive end-of-life care in patients with advanced cancer. J Clin Oncol 27(33):5559–5564CrossRefPubMedPubMedCentral
28.
Hwang IC, Keam B, Yun YH, Ahn HY, Kim YA (2015) Quality of life changes and intensive care preferences in terminal cancer patients. Palliat Support Care 13(5):1309–1316CrossRefPubMed
29.
Sharma RK, Prigerson HG, Penedo FJ, Maciejewski PK (2015) Male-female patient differences in the association between end-of-life discussions and receipt of intensive care near death. Cancer. 121(16):2814–2820CrossRefPubMed
30.
Kinoshita S, Miyashita M (2012) Evaluation of end-of-life cancer care in the ICU: perceptions of the bereaved family in Japan. Am J Hosp Palliat Care 30(3):225–230CrossRefPubMed
31.
Dennis BK (2014) Understanding participant experiences: reflections of a novice research participant. Int J Qual Methods 13(1):395–410CrossRef
32.
Wickson-Griffiths A, Kaasalainen S, Ploeg J, McAiney C (2014) Revisiting retrospective chart review: an evaluation of nursing home palliative and end-of-life care research. Palliat Med Care 1(2):8
33.
Sutton J, Austin Z (2015) Qualitative research: data collection, analysis, and management. Can J Hosp Pharm 68(3):226–231PubMedPubMedCentral
34.
Kastbom L, Milberg A, Karlsson M (2017) A good death from the perspective of palliative cancer patients. Support Care Cancer 25(3):933–939CrossRefPubMed
35.
Miyashita M, Morita T, Sato K, Hirai K, Shima Y, Uchitomi Y (2008) Good death inventory: a measure for evaluating good death from the bereaved family member’s perspective. J Pain Symptom Manag 35(5):486–498CrossRef
36.
Hammami MM, Al-Jawarneh Y, Hammami MB, Al Qadire M (2014) Information disclosure in clinical informed consent: "reasonable" patient's perception of norm in high-context communication culture. BMC Med Ethics 15:3CrossRefPubMedPubMedCentral
37.
Mohan D, Alexander SC, Garrigues SK, Arnold RM, Barnato AE (2010) Communication practices in physician decision-making for an unstable critically ill patient with end-stage cancer. J Palliat Med 13(8):949–956CrossRefPubMedPubMedCentral
38.
Virdun C, Luckett T, Lorenz K, Davidson PM, Phillips J (2017) Dying in the hospital setting: a meta-synthesis identifying the elements of end-of-life care that patients and their families describe as being important. Palliat Med 31(7):587–601CrossRefPubMed
39.
Phelps AC, Lauderdale KE, Alcorn S, Dillinger J, Balboni MT, Van Wert M et al (2012) Addressing spirituality within the care of patients at the end of life: perspectives of patients with advanced cancer, oncologists, and oncology nurses. J Clin Oncol 30(20):2538–2544CrossRefPubMedPubMedCentral
40.
Virdun C, Luckett T, Davidson PM, Phillips J (2015) Dying in the hospital setting: a systematic review of quantitative studies identifying the elements of end-of-life care that patients and their families rank as being most important. Palliat Med 29(9):774–796CrossRefPubMedPubMedCentral
41.
UK Department of Health (2008) End of life care strategy. In: Life PHQCfAAatEo, editor. London: UK Department of Health
Metadata
Title
End-of-life care preferences for people with advanced cancer and their families in intensive care units: a systematic review
Authors
Hanan M. Alyami
Raymond Javan Chan
Karen New
Publication date
01-09-2019
Publisher
Springer Berlin Heidelberg
Keyword
Care
Published in
Supportive Care in Cancer / Issue 9/2019
Print ISSN: 0941-4355
Electronic ISSN: 1433-7339
DOI
https://doi.org/10.1007/s00520-019-04844-8

Other articles of this Issue 9/2019

Supportive Care in Cancer 9/2019 Go to the issue

Original Article

A new model of early, integrated palliative care: palliative rehabilitation for newly diagnosed patients with non-resectable cancer

Commentary

Advancing supportive oncology care via collaboration between psycho-oncology and integrative medicine

Original Article

Need and demand for nutritional counselling and their association with quality of life, nutritional status and eating-related distress among patients with cancer receiving outpatient chemotherapy: a cross-sectional study

Original Article

Fear of disease progression in adult ambulatory patients with brain cancer: prevalence and clinical correlates

Original Article

Improving spiritual well-being among cancer patients: implications for clinical care

Original Article

Respectful encounters from healthcare professionals and return to work among 9032 long-term sick-listed due to cancer or due to other diagnoses: results from a Swedish population-based survey
Webinar | 19-02-2024 | 17:30 (CET)

Keynote webinar | Spotlight on antibody–drug conjugates in cancer

Watch now

Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.

Dr. Véronique Diéras
Prof. Fabrice Barlesi
Developed by: Springer Medicine
Image Credits