Skip to main content
Top
Published in: BMC Medical Informatics and Decision Making 1/2019

Open Access 01-12-2019 | Care | Research article

Considering patient safety in autonomous e-mental health systems – detecting risk situations and referring patients back to human care

Authors: Myrthe L. Tielman, Mark A. Neerincx, Claudia Pagliari, Albert Rizzo, Willem-Paul Brinkman

Published in: BMC Medical Informatics and Decision Making | Issue 1/2019

Login to get access

Abstract

Background

Digital health interventions can fill gaps in mental healthcare provision. However, autonomous e-mental health (AEMH) systems also present challenges for effective risk management. To balance autonomy and safety, AEMH systems need to detect risk situations and act on these appropriately. One option is sending automatic alerts to carers, but such ‘auto-referral’ could lead to missed cases or false alerts. Requiring users to actively self-refer offers an alternative, but this can also be risky as it relies on their motivation to do so.
This study set out with two objectives. Firstly, to develop guidelines for risk detection and auto-referral systems. Secondly, to understand how persuasive techniques, mediated by a virtual agent, can facilitate self-referral.

Methods

In a formative phase, interviews with experts, alongside a literature review, were used to develop a risk detection protocol. Two referral protocols were developed – one involving auto-referral, the other motivating users to self-refer. This latter was tested via crowd-sourcing (n = 160). Participants were asked to imagine they had sleeping problems with differing severity and user stance on seeking help. They then chatted with a virtual agent, who either directly facilitated referral, tried to persuade the user, or accepted that they did not want help. After the conversation, participants rated their intention to self-refer, to chat with the agent again, and their feeling of being heard by the agent.

Results

Whether the virtual agent facilitated, persuaded or accepted, influenced all of these measures. Users who were initially negative or doubtful about self-referral could be persuaded. For users who were initially positive about seeking human care, this persuasion did not affect their intentions, indicating that a simply facilitating referral without persuasion was sufficient.

Conclusion

This paper presents a protocol that elucidates the steps and decisions involved in risk detection, something that is relevant for all types of AEMH systems. In the case of self-referral, our study shows that a virtual agent can increase users’ intention to self-refer. Moreover, the strategy of the agent influenced the intentions of the user afterwards. This highlights the importance of a personalised approach to promote the user’s access to appropriate care.
Appendix
Available only for authorised users
Literature
1.
go back to reference WHO. Global burden of mental disorders and the need for a comprehensive, coordinated response from health and social sectors at the country level. 2012.. WHO. Global burden of mental disorders and the need for a comprehensive, coordinated response from health and social sectors at the country level. 2012..
2.
go back to reference Cartreine JA, Ahern DK, Locke SE. A roadmap to computer-based psychotherapy in the United States. Harv Rev Psychiatry. 2011;18(2):80–95.CrossRef Cartreine JA, Ahern DK, Locke SE. A roadmap to computer-based psychotherapy in the United States. Harv Rev Psychiatry. 2011;18(2):80–95.CrossRef
3.
go back to reference Lyons C, Hopley P, Horrocks J. A decade of stigma and discrimination in mental health:plus ça change, plus c’est la même chose (the morethings change, the more they stay the same). J Psychiatr Ment Health Nurs. 2009;16:501–7.CrossRef Lyons C, Hopley P, Horrocks J. A decade of stigma and discrimination in mental health:plus ça change, plus c’est la même chose (the morethings change, the more they stay the same). J Psychiatr Ment Health Nurs. 2009;16:501–7.CrossRef
4.
go back to reference Donker T, Blankers M, Hedman E, Ljótsson B, Petrie K, Christensen H. Economic evaluations of Internet interventions for mental health: a systematic review. Psychological Medicine. 2015:1–20. Donker T, Blankers M, Hedman E, Ljótsson B, Petrie K, Christensen H. Economic evaluations of Internet interventions for mental health: a systematic review. Psychological Medicine. 2015:1–20.
5.
go back to reference Bower P, Gilbody S. Stepped care in psychological therapies: access, effectiveness and efficiency. Br J Psychiatry. 2005;186(1):11–7.CrossRef Bower P, Gilbody S. Stepped care in psychological therapies: access, effectiveness and efficiency. Br J Psychiatry. 2005;186(1):11–7.CrossRef
6.
go back to reference Luxton DD. Recommendations for the ethical use and design of artificial intelligent care providers. Artif Intell Med. 2014;62(1):1–10.CrossRef Luxton DD. Recommendations for the ethical use and design of artificial intelligent care providers. Artif Intell Med. 2014;62(1):1–10.CrossRef
7.
go back to reference Gratch J, Morency LP, Scherer S, Stratou G, Boberg J, Koenig S, et al. User-state sensing for virtual health agents and TeleHealth applications. Studies in Health Technology Informaticts. 2013;184:151–7. Gratch J, Morency LP, Scherer S, Stratou G, Boberg J, Koenig S, et al. User-state sensing for virtual health agents and TeleHealth applications. Studies in Health Technology Informaticts. 2013;184:151–7.
8.
go back to reference DeVault D, Artstein R, Benn G, Dey T, Fast E, Gainer A, et al. SimSensei Kiosk: A Virtual Human Interviewer for HealHealth Decision Support. In AAMAS; 2014. DeVault D, Artstein R, Benn G, Dey T, Fast E, Gainer A, et al. SimSensei Kiosk: A Virtual Human Interviewer for HealHealth Decision Support. In AAMAS; 2014.
9.
go back to reference Rizzo AA, Lange B, Buckwalter JG, Forbell E, Kim J, Sagae K, et al. An Intelligent Virtual Human System for Providing Healthcare Information and Support. Medicine meets Virtual Reality. 2011. Rizzo AA, Lange B, Buckwalter JG, Forbell E, Kim J, Sagae K, et al. An Intelligent Virtual Human System for Providing Healthcare Information and Support. Medicine meets Virtual Reality. 2011.
10.
go back to reference Pagliari C, Burton C, McKinstry B, Szentatotai A, David D. Blanco AS, et al. psychosocial implications of avatar use in supporting therapy for depression. Stud Health Technol Inform. 2012;181:329–33.PubMed Pagliari C, Burton C, McKinstry B, Szentatotai A, David D. Blanco AS, et al. psychosocial implications of avatar use in supporting therapy for depression. Stud Health Technol Inform. 2012;181:329–33.PubMed
11.
go back to reference Wolters M, Martinez-Miranda J, Hastie H, Matheson C. Managing Data in Help4Mood. In 2nd International Workshop on Computing Paradigms for Mental Health - MindCare 2012; 2012. Wolters M, Martinez-Miranda J, Hastie H, Matheson C. Managing Data in Help4Mood. In 2nd International Workshop on Computing Paradigms for Mental Health - MindCare 2012; 2012.
12.
go back to reference Kordy H, Backenstrass M, Hüsing J, Wolf M, Aulich K, Bürg M, et al. Supportive monitoring and disease management through the internet: an internet-delivered intervention strategy for recurrent depression. Contemporary Clinical Trials. 2013;36(2):327–37.CrossRef Kordy H, Backenstrass M, Hüsing J, Wolf M, Aulich K, Bürg M, et al. Supportive monitoring and disease management through the internet: an internet-delivered intervention strategy for recurrent depression. Contemporary Clinical Trials. 2013;36(2):327–37.CrossRef
13.
go back to reference Robinson J, Hetrick S, Cox G, Bendall S, Yung A, Pirkis J. The safety and acceptability of delivering an online intervention to secondary students at risk of suicide: findings from a pilot study. Early Intervention in Psychiatry. 2015;9(6):498–506.CrossRef Robinson J, Hetrick S, Cox G, Bendall S, Yung A, Pirkis J. The safety and acceptability of delivering an online intervention to secondary students at risk of suicide: findings from a pilot study. Early Intervention in Psychiatry. 2015;9(6):498–506.CrossRef
14.
go back to reference Tielman ML, Neerincx MA, Bidarra R, Kybartas B, Brinkman WP. A therapy system for post-traumatic stress disorder using a virtual agent and virtual storytelling to reconstruct traumatic memories. J Med Syst. 2017;41. Tielman ML, Neerincx MA, Bidarra R, Kybartas B, Brinkman WP. A therapy system for post-traumatic stress disorder using a virtual agent and virtual storytelling to reconstruct traumatic memories. J Med Syst. 2017;41.
15.
go back to reference Spence J, Titov N, Johnston L, Jones MP, Dear BF. Internet-based trauma-focused cognitive behavioural therapy for PTSD with and without exposure components: a randomised controlled trial. J Affect Disord. 2014;162(20):73–80.CrossRef Spence J, Titov N, Johnston L, Jones MP, Dear BF. Internet-based trauma-focused cognitive behavioural therapy for PTSD with and without exposure components: a randomised controlled trial. J Affect Disord. 2014;162(20):73–80.CrossRef
16.
go back to reference Kasckow J, Zickmund S, Rotondi A, Mrkva A, Gurklis J, Chinman M, et al. Development of Telehealth Dialogues for Monitoring Suicidal Patients with Schizophrenia: Consumer Feedback. Community Mental Health Journal. 2013; Brief Report: p. 1–4. Kasckow J, Zickmund S, Rotondi A, Mrkva A, Gurklis J, Chinman M, et al. Development of Telehealth Dialogues for Monitoring Suicidal Patients with Schizophrenia: Consumer Feedback. Community Mental Health Journal. 2013; Brief Report: p. 1–4.
17.
go back to reference Kasckow J, Zickmund S, Rotondi A, Welch A, Gurklis J, Chinman M, et al. Optimizing Scripted Dialogues for an e-Health Intervention for Suicidal Veterans with Major Depression. Community Ment Health J. 2015;15(5):509–12. Kasckow J, Zickmund S, Rotondi A, Welch A, Gurklis J, Chinman M, et al. Optimizing Scripted Dialogues for an e-Health Intervention for Suicidal Veterans with Major Depression. Community Ment Health J. 2015;15(5):509–12.
18.
go back to reference Andrews G, Newby JM, Williams AD. Internet-delivered cognitive behavior therapy for anxiety disorders is here to stay. Current psychiatry reports. 2015;17:533.CrossRef Andrews G, Newby JM, Williams AD. Internet-delivered cognitive behavior therapy for anxiety disorders is here to stay. Current psychiatry reports. 2015;17:533.CrossRef
19.
go back to reference Christensen HM, Batterham PJ, O’Dea B. E-health interventions for suicide prevention. Int J Environ Res Public Health. 2014;11(8):8193–212.CrossRef Christensen HM, Batterham PJ, O’Dea B. E-health interventions for suicide prevention. Int J Environ Res Public Health. 2014;11(8):8193–212.CrossRef
20.
go back to reference van Hemert AM, Kerkhof AJFM, de Keijser J, Verwey B, van Boven C, Hummelen JW, et al. Multidisciplinaire richtlijn diagnostiek en behandeling van suïcidaal gedrag. In.; 2012. van Hemert AM, Kerkhof AJFM, de Keijser J, Verwey B, van Boven C, Hummelen JW, et al. Multidisciplinaire richtlijn diagnostiek en behandeling van suïcidaal gedrag. In.; 2012.
21.
go back to reference Knight K, BAppSci, Kenny A, Endacott R. Assessing clinical urgency via telephone in rural Australia. Nurs Health Sci. 2015;17:201–7.CrossRef Knight K, BAppSci, Kenny A, Endacott R. Assessing clinical urgency via telephone in rural Australia. Nurs Health Sci. 2015;17:201–7.CrossRef
22.
go back to reference Sands N, Elsom S, Gerdtz M, Henderson K, Keppich-Arnold S, Droste N, et al. Identifying the core competencies of mental health telephone triage. J Clin Nurs. 2013;22:3203–16.CrossRef Sands N, Elsom S, Gerdtz M, Henderson K, Keppich-Arnold S, Droste N, et al. Identifying the core competencies of mental health telephone triage. J Clin Nurs. 2013;22:3203–16.CrossRef
23.
go back to reference Belnap BH, Schulberg HC, He F, Mazumdar S, Reynolds CF, Rollman BL. Electronic protocol for suicide risk management in research participants. J Psychosom Res. 2015;78:340–5.CrossRef Belnap BH, Schulberg HC, He F, Mazumdar S, Reynolds CF, Rollman BL. Electronic protocol for suicide risk management in research participants. J Psychosom Res. 2015;78:340–5.CrossRef
24.
go back to reference Rollman BL, Belnap BH, Mazumdar S, Abebe KZ, Karp JF, Lenze EJ, et al. Telephone-delivered stepped collaborative Care for Treating Anxiety in primary care: a randomized controlled trial. J Gen Intern Med. 2017;32:245–55.CrossRef Rollman BL, Belnap BH, Mazumdar S, Abebe KZ, Karp JF, Lenze EJ, et al. Telephone-delivered stepped collaborative Care for Treating Anxiety in primary care: a randomized controlled trial. J Gen Intern Med. 2017;32:245–55.CrossRef
25.
go back to reference Tielman M, Pagliari C, Brinkman WP. Risk detection in smart mental-health applications; 2015. Tielman M, Pagliari C, Brinkman WP. Risk detection in smart mental-health applications; 2015.
26.
go back to reference Pompili M, Sher L, Serafini G, Forte A, Innamorati M, Dominici G, et al. Posttraumatic Stress Disorder and Suicide Risk Among Veterans. J Nervous and Mental Disease. 2013. Pompili M, Sher L, Serafini G, Forte A, Innamorati M, Dominici G, et al. Posttraumatic Stress Disorder and Suicide Risk Among Veterans. J Nervous and Mental Disease. 2013.
27.
go back to reference Grant BF, Stinson FS, Dawson DA, Chou SP, Dufour MC, Compton W, et al. Prevalence and co-occurrence of substance use disorders and IndependentMood and anxiety disorders results from the National Epidemiologic Survey on alcohol and RelatedConditions. Arch Gen Psychiatry. 2004;61:807–16.CrossRef Grant BF, Stinson FS, Dawson DA, Chou SP, Dufour MC, Compton W, et al. Prevalence and co-occurrence of substance use disorders and IndependentMood and anxiety disorders results from the National Epidemiologic Survey on alcohol and RelatedConditions. Arch Gen Psychiatry. 2004;61:807–16.CrossRef
28.
go back to reference Simon GE, Rutter CM, Peterson D, Oliver M, Whiteside U, Operskalski B, et al. Do PHQ depression questionnaires completed during outpatient visits predict subsequent suicide attempt or suicide death? Psychiatr Serv. 2013;64(12):1195–202.CrossRef Simon GE, Rutter CM, Peterson D, Oliver M, Whiteside U, Operskalski B, et al. Do PHQ depression questionnaires completed during outpatient visits predict subsequent suicide attempt or suicide death? Psychiatr Serv. 2013;64(12):1195–202.CrossRef
29.
go back to reference Gould MS. Suicide and the media. In Annals of the New York Academy of Sciences; 2001. Gould MS. Suicide and the media. In Annals of the New York Academy of Sciences; 2001.
30.
go back to reference Koocher GP, Keith-Speigel P. Ethics in psychology and the mental health professions: standards and cases (oxford textbooks in clinical psychology): Oxford University press; 2008. Koocher GP, Keith-Speigel P. Ethics in psychology and the mental health professions: standards and cases (oxford textbooks in clinical psychology): Oxford University press; 2008.
31.
go back to reference Shevat A. Designing Bots Rufino A, editor.: O'Reilly; 2015. Shevat A. Designing Bots Rufino A, editor.: O'Reilly; 2015.
32.
go back to reference Kampmann IL, Emmelkamp PMG, Hartanto D, Brinkman WP, Zijlstra BJH, Morina N. Exposure to virtual social interactions in the treatment of social anxiety disorder: a randomized controlled trial. Behav Res Ther. 2016;77:147–56.CrossRef Kampmann IL, Emmelkamp PMG, Hartanto D, Brinkman WP, Zijlstra BJH, Morina N. Exposure to virtual social interactions in the treatment of social anxiety disorder: a randomized controlled trial. Behav Res Ther. 2016;77:147–56.CrossRef
33.
go back to reference Simons HW, Jones JG. Persuasion in society: Routledge; 2011. Simons HW, Jones JG. Persuasion in society: Routledge; 2011.
34.
go back to reference Fogg BJ. A behavior model for persuasive design. In Proceedings of the 4th International Conference on Persuasive Technology; 2009. Fogg BJ. A behavior model for persuasive design. In Proceedings of the 4th International Conference on Persuasive Technology; 2009.
35.
go back to reference Michie S, van Stralen MM, West R. The behaviour change wheel: A new method for characterising and designing behaviour change intervention. Implementation Science. 2011;6:42.CrossRef Michie S, van Stralen MM, West R. The behaviour change wheel: A new method for characterising and designing behaviour change intervention. Implementation Science. 2011;6:42.CrossRef
36.
go back to reference Thaler RH, Sunstein CR. Nudge: improving decisions about health, wealth, and happiness: Yale University press; 2008. Thaler RH, Sunstein CR. Nudge: improving decisions about health, wealth, and happiness: Yale University press; 2008.
37.
go back to reference M.Ohayon M. Epidemiology of insomnia: what we know and what we still need to learn. Sleep Medicine Reviews. 2002; 6: p. 97–111. M.Ohayon M. Epidemiology of insomnia: what we know and what we still need to learn. Sleep Medicine Reviews. 2002; 6: p. 97–111.
38.
go back to reference Thayaparan AJ, Mahdi E. The patient satisfaction questionnaire short form (PSQ-18) as an adaptable, reliable, and validated tool for use in various settings. Med Educ Online. 2013;18. Thayaparan AJ, Mahdi E. The patient satisfaction questionnaire short form (PSQ-18) as an adaptable, reliable, and validated tool for use in various settings. Med Educ Online. 2013;18.
39.
go back to reference Hall MA, Zheng B, Dugan E, Camacho F, Kidd KE. Measuring patients’ Trust in Their Primary Care Providers. Med Care Res Rev. 2002;59:293–318.CrossRef Hall MA, Zheng B, Dugan E, Camacho F, Kidd KE. Measuring patients’ Trust in Their Primary Care Providers. Med Care Res Rev. 2002;59:293–318.CrossRef
41.
go back to reference McFadden D. In: Zarembka P, editor. Frontiers in Econometrics. New York: Academic Press; 1974. p. 105–42. McFadden D. In: Zarembka P, editor. Frontiers in Econometrics. New York: Academic Press; 1974. p. 105–42.
42.
go back to reference Cohen J. A power primer. Quantative Methods in Psychology. 1992;112:155–9. Cohen J. A power primer. Quantative Methods in Psychology. 1992;112:155–9.
43.
go back to reference Prochaska JO, DiClemente CC. In: Norcross JC, Goldfried MR, editors. The transtheoretical approach: Oxford University Press; 2005. p. 147–71. Prochaska JO, DiClemente CC. In: Norcross JC, Goldfried MR, editors. The transtheoretical approach: Oxford University Press; 2005. p. 147–71.
44.
go back to reference Provoost S, Lau HM, Ruwaard J, Riper H. Embodied conversational agents in clinical psychology: a scoping review. J Med Internet Res. 2017;19:e151.CrossRef Provoost S, Lau HM, Ruwaard J, Riper H. Embodied conversational agents in clinical psychology: a scoping review. J Med Internet Res. 2017;19:e151.CrossRef
45.
go back to reference Schmidt U, Wykes T. E-mental health – a land of unlimited possibilities. J Ment Health. 2012;21:327–31.CrossRef Schmidt U, Wykes T. E-mental health – a land of unlimited possibilities. J Ment Health. 2012;21:327–31.CrossRef
46.
go back to reference Blenkinsopp A, Bond C, Britten N, Feely M, Green P, George C, et al. From compliance to concordance : achieving shared goals in medicine taking Sharp M, Dohme RPSoGB, editors.; 1997. Blenkinsopp A, Bond C, Britten N, Feely M, Green P, George C, et al. From compliance to concordance : achieving shared goals in medicine taking Sharp M, Dohme RPSoGB, editors.; 1997.
47.
go back to reference Zivin K, Kim HM, McCarthy JF, Austin KL, Hoggatt KJ, Walters H, et al. Suicide mortality among individuals receiving treatment for depression in the veterans affairs health system: associations with patient and treatment setting characteristics. Am J Public Health. 2007;97(12):2193–8.CrossRef Zivin K, Kim HM, McCarthy JF, Austin KL, Hoggatt KJ, Walters H, et al. Suicide mortality among individuals receiving treatment for depression in the veterans affairs health system: associations with patient and treatment setting characteristics. Am J Public Health. 2007;97(12):2193–8.CrossRef
48.
go back to reference Turecki G, Brent DA. Suicide and suicidal behaviour. Lancet. 2016;387:1227–39.CrossRef Turecki G, Brent DA. Suicide and suicidal behaviour. Lancet. 2016;387:1227–39.CrossRef
Metadata
Title
Considering patient safety in autonomous e-mental health systems – detecting risk situations and referring patients back to human care
Authors
Myrthe L. Tielman
Mark A. Neerincx
Claudia Pagliari
Albert Rizzo
Willem-Paul Brinkman
Publication date
01-12-2019
Publisher
BioMed Central
Keyword
Care
Published in
BMC Medical Informatics and Decision Making / Issue 1/2019
Electronic ISSN: 1472-6947
DOI
https://doi.org/10.1186/s12911-019-0796-x

Other articles of this Issue 1/2019

BMC Medical Informatics and Decision Making 1/2019 Go to the issue