Published in:
01-11-2014 | Prevention (L Sperling and D Gaita, Section Editors)
Cardiovascular Disease Associated with the Human Immunodeficiency Virus: An Update
Authors:
Thomas S. Metkus Jr., MD, Todd T. Brown, MD, PhD, Wendy S. Post, MD, MS
Published in:
Current Treatment Options in Cardiovascular Medicine
|
Issue 11/2014
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Opinion statement
With the advent of increasingly available antiretroviral therapy (ART), the life expectancy of HIV-infected persons is increasing. As they age, HIV-infected persons have increased propensity to typical diseases of aging including cardiovascular disease and accelerated atherosclerosis. The pathogenesis of HIV-associated atherosclerosis is complex and involves a state of chronic inflammation, exposure to traditional risk factors, and metabolic side effects of ART. Treatment of HIV-associated atherosclerosis should include special attention to drug-drug interactions and is best accomplished by a multidisciplinary team experienced in the care of HIV-infected persons.