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Published in: Neurological Sciences 5/2016

01-05-2016 | Original Article

Cardiovascular autonomic dysfunctions in elderly patients with essential tremor: comparison with healthy controls

Authors: Joong-Seok Kim, Yoon-Sang Oh, Hyung-Eun Park, Si-Hoon Lee, Jeong-Wook Park, In-Uk Song, Jae-Young An, Hun-Jun Park, Byung-Chul Son, Kwang-Soo Lee

Published in: Neurological Sciences | Issue 5/2016

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Abstracts

Questionnaire-based analyses show that patients with essential tremor (ET) may have several autonomic dysfunctions, especially in the cardiovascular and genitourinary domains; yet the laboratory correlates of autonomic dysfunction in ET are unknown and have not been studied. Herein, we explored whether sympathetic and parasympathetic functions differed between control subjects and patients with ET. Seventy-five elderly patients with ET were enrolled in this study, along with 25 age-matched controls. Orthostatic vital signs, ambulatory 24-h blood pressure monitoring and 24-h Holter monitoring values were recorded and metaiodobenzylguanidine (MIBG) uptake was assessed using the heart-to-mediastinum ratio (H/M ratio). The frequencies of orthostatic hypotension, supine hypertension, nocturnal hypertension and non-dipping were not different between the ET patients and the controls, although ET patients had more episodes of orthostatic intolerance. The ET group also had similar heart rate variations as the control group for all the time-domains. The mean H/M ratios for the ET group were not statistically different from that of the control group. This result proves that the autonomic control of the cardiovascular system is normal in ET.
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Metadata
Title
Cardiovascular autonomic dysfunctions in elderly patients with essential tremor: comparison with healthy controls
Authors
Joong-Seok Kim
Yoon-Sang Oh
Hyung-Eun Park
Si-Hoon Lee
Jeong-Wook Park
In-Uk Song
Jae-Young An
Hun-Jun Park
Byung-Chul Son
Kwang-Soo Lee
Publication date
01-05-2016
Publisher
Springer Milan
Published in
Neurological Sciences / Issue 5/2016
Print ISSN: 1590-1874
Electronic ISSN: 1590-3478
DOI
https://doi.org/10.1007/s10072-015-2465-x

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