Published in:
Open Access
01-12-2023 | Cardiopulmonary Resuscitation | Research
Skeletal muscle oxygenation during cardiopulmonary resuscitation as a predictor of return of spontaneous circulation: a pilot study
Authors:
Miha Košir, Hugon Možina, Matej Podbregar
Published in:
European Journal of Medical Research
|
Issue 1/2023
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Abstract
Background
Near-infrared spectroscopy (NIRS) provides regional tissue oxygenation (rSO2) even in pulseless states, such as out-of-hospital cardiac arrest (OHCA). Brain rSO2 seems to be important predictor of return of spontaneous circulation (ROSC) during cardiopulmonary resuscitation (CPR). Aim of our study was to explore feasibility for monitoring and detecting changes of skeletal muscle rSO2 during resuscitation.
Methods
Skeletal muscle and brain rSO2 were measured by NIRS (SenSmart Model X-100, Nonin, USA) during CPR in adult patient with OHCA. Start (basal) rSO2, maximal during CPR (maximal) and difference between maximal–minimal rSO2 (delta-rSO2), were recorded. Patients were divided into ROSC and NO-ROSC group.
Results
20 patients [age: 66.0ys (60.5–79.5), 65% male] with OHCA [50% witnessed, 70% BLS, time to ALS 13.5 min (11.0–19.0)] were finally analyzed. ROSC was confirmed in 5 (25%) patients. Basal and maximal skeletal muscle rSO2 were higher in ROSC compared to NO-ROSC group [49.0% (39.7–53.7) vs. 15.0% (12.0–25.2), P = 0.006; 76.0% (52.7–80.5) vs. 34.0% (18.0–49.5), P = 0.005, respectively]. There was non-linear cubic relationship between time of collapse and basal skeletal muscle rSO2 in witnessed OHCA and without BLS (F-ratio = 9.7713, P = 0.0261). There was correlation between maximal skeletal muscle and brain rSO2 (n = 18, rho: 0.578, P = 0.0121).
Conclusions
Recording of skeletal muscle rSO2 during CPR in patients with OHCA is feasible. Basal and maximal skeletal muscle rSO2 were higher in ROSC compared to NO-ROSC group.