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European Radiology

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01-12-2019 | Cardiomyopathy | Cardiac

Inter-vendor reproducibility and accuracy of segmental left ventricular strain measurements using CMR feature tracking

Authors: Monica Dobrovie, Manuel Barreiro-Pérez, Davide Curione, Rolf Symons, Piet Claus, Jens-Uwe Voigt, Jan Bogaert

Published in: European Radiology | Issue 12/2019

Abstract

Objectives

Our aim was to evaluate the inter-vendor reproducibility of cardiovascular MR feature tracking (CMR-FT) for the measurement of segmental strain (SS) of the left ventricle (LV) as well as to test the accuracy of CMR-FT to detect regional myocardial pathology.

Methods

We selected 45 patients: 15 with normal CMR findings, 15 with dilated cardiomyopathy, and 15 with acute myocardial infarction. Segmental longitudinal, circumferential, and radial strains were assessed with 4 different software. The inter-vendor difference as well as intra- and inter-observer variability was investigated. Furthermore, the accuracy of CMR-FT for the detection of structural (infarcted segments) as well as functional pathology (septal vs. lateral wall strain in left bundle branch block) was tested.

Results

Between vendors, there were significant differences in values for all strains (p < 0.001). The software using a non-rigid algorithm for image registration and segmentation demonstrated the best intra- as well as inter-observer variability with interclass correlation coefficient (ICC) > 0.962 and coefficient of variation (CV) < 24%. For infarct location, the same software yielded the highest area under the curve values for radial and circumferential SS (0.872 and 0.859, respectively). One of the other three software using optical flow technology performed best for longitudinal SS (0.799) and showed the largest differences in SS between septum and lateral wall in the dilated cardiomyopathy group.

Conclusion

SS values obtained by CMR-FT are not interchangeable between vendors, and intra- and inter-observer reproducibility shows substantial variability among vendors. Overall, the different packages score relatively well to depict focal structural or functional LV pathology.

Key Points

• Segmental myocardial strain values obtained by CMR feature tracking are not interchangeable between different vendors.

• Intra- and inter-observer reproducibility shows substantial variability among vendors.

• Segmental myocardial strains measured by CMR feature tracking score relatively well to depict focal structural or functional LV pathology.

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Title: Inter-vendor reproducibility and accuracy of segmental left ventricular strain measurements using CMR feature tracking
Authors: Monica Dobrovie
Manuel Barreiro-Pérez
Davide Curione
Rolf Symons
Piet Claus
Jens-Uwe Voigt
Jan Bogaert
Publication date: 01-12-2019
Publisher: Springer Berlin Heidelberg
Keywords: Cardiomyopathy
Left Bundle Branch Block
Myocardial Infarction
Published in: European Radiology / Issue 12/2019
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-019-06315-4

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Inter-vendor reproducibility and accuracy of segmental left ventricular strain measurements using CMR feature tracking

Abstract

Objectives

Methods

Results

Conclusion

Key Points

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objectives

Methods

Results

Conclusion

Key Points

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