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BMC Pediatrics

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Open Access 01-12-2013 | Research article

Cardiometabolic risk factors and quality of life in severely obese children and adolescents in the Netherlands

Authors: Sabine Makkes, Carry M Renders, Judith E Bosmans, Olga H van der Baan-Slootweg, Jacob C Seidell

Published in: BMC Pediatrics | Issue 1/2013

Abstract

Background

The prevalence of severe obesity in children and adolescents is increasing. However, little is known about cardiometabolic risk factors and quality of life of children with severe obesity.

Therefore, the aim of this study was to assess the demographic characteristics and the prevalence of cardiometabolic risk factors and quality of life in severely obese children and adolescents undergoing intensive inpatient treatment for obesity.

Methods

Data were collected between August 2009 and April 2011 on 16 children (8-13y) and 64 adolescents (13-19y) with severe obesity (SDS-BMI >= 3.0 or SDS-BMI >= 2.3 and comorbidity) participating in an RCT evaluating two intensive inpatient treatment programs for obesity. Demographic, anthropometric, clinical characteristics and two components of the EuroQol for the assessment of quality of life are described.

Results

Eighty percent of participants in this study had at least one cardiometabolic risk factor in addition to severe obesity. Low HDL-cholesterol and hypertension were most prevalent (65.0% respectively 31.2%). The highest significant correlations were found between SDS-BMI and SDS-waist circumference, fasting plasma insulin and HOMA-IR (correlation coefficients respectively 0.80, 0.49, and 0.48). With regard to quality of life, the mean utility score of the participants was 0.79 on a scale of 0.0 to 1.0 on the EuroQol questionnaire and their mean individual valuation was 69.1 on a scale of 0 to100.

Conclusion

Cardiometabolic risk factors are already highly prevalent in this group of severely obese children and adolescents. The score of 69.1 found for quality of life in this study suggests that participants experience important limitations in their quality of life. However, quality of life is not associated with the prevalence of cardiometabolic risk factors.

Trial registration

Netherlands Trial Register (NTR1678, registered 20-Feb-2009)

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The pre-publication history for this paper can be accessed here:http://www.biomedcentral.com/1471-2431/13/62/prepub

Title: Cardiometabolic risk factors and quality of life in severely obese children and adolescents in the Netherlands
Authors: Sabine Makkes
Carry M Renders
Judith E Bosmans
Olga H van der Baan-Slootweg
Jacob C Seidell
Publication date: 01-12-2013
Publisher: BioMed Central
Published in: BMC Pediatrics / Issue 1/2013
Electronic ISSN: 1471-2431
DOI: https://doi.org/10.1186/1471-2431-13-62

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Cardiometabolic risk factors and quality of life in severely obese children and adolescents in the Netherlands

Abstract

Background

Methods

Results

Conclusion

Trial registration

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

Trial registration

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