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Strahlentherapie und Onkologie
Published in: Strahlentherapie und Onkologie 12/2018

01-12-2018 | Literatur kommentiert

Carboplatin verbessert nicht die Wirksamkeit der adjuvanten Radiotherapie bei fortgeschrittenen kutanen Plattenepithelkarzinomen der Kopf-Hals-Region

Authors: Prof. Dr. med. Robert Michael Hermann, Prof. Dr. med. Hans Christiansen

Published in: Strahlentherapie und Onkologie | Issue 12/2018

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Auszug

Die optimale postoperative Behandlung von Patienten mit lokal fortgeschrittenen kutanen Plattenepithelkarzinomen der Kopf-Hals-Region ist noch ungeklärt. Bei erhöhten Risiken für ein Rezidiv ist die adjuvante Radiotherapie (RT) etabliert. In Analogie zur Therapie der mukosalen Plattenepithelkarzinome dieser Region wird aber auch eine adjuvante Radiochemotherapie (RCT) empfohlen. Die kommentierte Arbeit publiziert die Ergebnisse der ersten prospektiv randomisierten Studie zur Frage, ob Patienten in dieser Situation von einer adjuvanten RCT im Vergleich zur alleinigen adjuvanten RT profitieren. …
Literature
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Veness MJ, Morgan GJ, Palme CE et al (2005) Surgery and adjuvant radiotherapy in patients with cutaneous head and neck squamous cell carcinoma metastatic to lymph nodes: combined treatment should be considered best practice. Laryngoscope 115:870–875CrossRef
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Amoils M, Lee CS, Sunwoo J et al (2017) Node-positive cutaneous squamous cell carcinoma of the head and neck: Survival, high-risk features, and adjuvant chemoradiotherapy outcomes. Head Neck 39:881–885CrossRef
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Metadata
Title
Carboplatin verbessert nicht die Wirksamkeit der adjuvanten Radiotherapie bei fortgeschrittenen kutanen Plattenepithelkarzinomen der Kopf-Hals-Region
Authors
Prof. Dr. med. Robert Michael Hermann
Prof. Dr. med. Hans Christiansen
Publication date
01-12-2018
Publisher
Springer Berlin Heidelberg
Published in
Strahlentherapie und Onkologie / Issue 12/2018
Print ISSN: 0179-7158
Electronic ISSN: 1439-099X
DOI
https://doi.org/10.1007/s00066-018-1375-2

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