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Journal of General Internal Medicine
Published in: Journal of General Internal Medicine 12/2015

01-12-2015 | Capsule Commentary

Capsule Commentary on Al-Khatib et al., Future Research Prioritization: Implantable Cardioverter Defibrillator Therapy in Older Patients

Authors: Nicoletta Riva, MD, Christian Borg Xuereb, PhD

Published in: Journal of General Internal Medicine | Issue 12/2015

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Excerpt

Implantable cardioverter defibrillators (ICDs) have been consistently shown to reduce mortality rates in patients who survive ventricular arrhythmias or cardiac arrest (secondary prevention). In primary prevention of sudden cardiac death (SCD), the use of an ICD is recommended in selected patients with systolic heart failure (ischemic or non-ischemic cardiomyopathy with New York Heart Association [NYHA] functional class II or III and left ventricular eject fraction [LVEF] ≤ 35 %, or post-ischemic heart disease with NYHA class I and LVEF ≤ 30 %), receiving optimal medical therapy and with life expectancy of more than 1 year.1 …
Literature
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Yancy CW, Jessup M, Bozkurt B, Butler J, Casey DE Jr, Drazner MH, et al. American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. 2013 ACCF/AHA guideline for the management of heart failure: a report of the American College of Cardiology Foundation/American Heart Association Task Force on practice guidelines. Circulation. 2013;128(16):e240–327.CrossRefPubMed
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Shah RU, Chang TI, Fonarow GC. Comparative effectiveness research in heart failure therapies: women, elderly patients, and patients with kidney disease. Heart Fail Clin. 2013;9(1):79–92.PubMedCentralCrossRefPubMed
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Hess PL, Al-Khatib SM, Han JY, Edwards R, Bardy GH, Bigger JT, et al. Survival benefit of the primary prevention implantable cardioverter-defibrillator among older patients: does age matter? An analysis of pooled data from 5 clinical trials. Circ Cardiovasc Qual Outcomes. 2015;8(2):179–86.CrossRefPubMed
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Al-Khatib SM, Gierisch JM, Crowley MJ, Coeytaux RR, Myers ER, Kendrick A, Sanders GD. Future Research Prioritization: Implantable Cardioverter Defibrillator Therapy in Older Patients. J Gen Intern Med. 2015. doi:10.​1007/​s11606-015-3411-6.PubMed
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Chalmers I, Bracken MB, Djulbegovic B, Garattini S, Grant J, Gülmezoglu AM, Howells DW, Ioannidis JP, Oliver S. How to increase value and reduce waste when research priorities are set. Lancet. 2014;383(9912):156–65.CrossRefPubMed
Metadata
Title
Capsule Commentary on Al-Khatib et al., Future Research Prioritization: Implantable Cardioverter Defibrillator Therapy in Older Patients
Authors
Nicoletta Riva, MD
Christian Borg Xuereb, PhD
Publication date
01-12-2015
Publisher
Springer US
Published in
Journal of General Internal Medicine / Issue 12/2015
Print ISSN: 0884-8734
Electronic ISSN: 1525-1497
DOI
https://doi.org/10.1007/s11606-015-3432-1

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