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Published in: BMC Health Services Research 1/2021

Open Access 01-12-2021 | Cancer of Unknown Primary | Research article

Mono-institutional retrospective cohort analysis of the insurance status dependent access to ENT-professionals and survival in head and neck squamous cell carcinoma

Authors: Andreas Knopf, Simon Teutsch, Henning Bier

Published in: BMC Health Services Research | Issue 1/2021

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Abstract

Background

To access the influence of insurance status on time of diagnosis, quality of treatment and survival in head and neck squamous cell carcinoma (HNSCC).

Methods

This mono-institutional retrospective cohort analysis included all HNSCC patients (n = 1,054) treated between 2001 and 2011, and subdivided the cohort according to the insurance status. Differences between the groups were analyzed using the Chi square and the unpaired student’s t-test. Survival rates were calculated by Kaplan-Meier and Cox regression for forward selection.

Results

Nine hundred twenty-five patients showed general, 129 private insurance. The 2 groups were equal regarding age, gender, tumor localization, therapy, and N/M/G/R-status. The T-status differed significantly between the groups showing more advanced tumors in patients with general insurance (p = 0.002). While recurrence-free survival was comparable in both groups, overall survival was significantly better in private patients (p = 0.009). The time frame between first symptom and diagnosis was equal in both groups.

Conclusions

The time frame between subjective percipience of first symptom and final therapy did not differ between the groups. In our cohort, access to otorhinolaryngological specialists is favorable in both, patients with general and private insurance. Recurrence-free survival was comparable in both groups, indicating successful HNSCC treatment both groups. However, overall survival was significantly better in patients with private insurance suggesting other socioeconomic factors influencing survival.
Literature
1.
go back to reference Gesellschaft RK.-I.H.u.d. and d.e.K.i.D.e.V, Herausgeber, Krebs in Deutschland 2013–2014. 11: p. 24–26. Gesellschaft RK.-I.H.u.d. and d.e.K.i.D.e.V, Herausgeber, Krebs in Deutschland 2013–2014. 11: p. 24–26.
2.
go back to reference Panth N, et al. Insurance status, stage of presentation, and survival among female patients with head and neck cancer. Laryngoscope. 2020;130(2):385–91.PubMedCrossRef Panth N, et al. Insurance status, stage of presentation, and survival among female patients with head and neck cancer. Laryngoscope. 2020;130(2):385–91.PubMedCrossRef
4.
go back to reference Rohlfing ML, et al. Insurance status as a predictor of mortality in patients undergoing head and neck cancer surgery. Laryngoscope. 2017;127(12):2784–9.PubMedPubMedCentralCrossRef Rohlfing ML, et al. Insurance status as a predictor of mortality in patients undergoing head and neck cancer surgery. Laryngoscope. 2017;127(12):2784–9.PubMedPubMedCentralCrossRef
5.
go back to reference Gupta A, et al. Impact of the insurance type of head and neck cancer patients on their hospitalization utilization patterns. Cancer. 2018;124(4):760–8.PubMedCrossRef Gupta A, et al. Impact of the insurance type of head and neck cancer patients on their hospitalization utilization patterns. Cancer. 2018;124(4):760–8.PubMedCrossRef
6.
go back to reference Takenaka Y, et al. Health insurance status and survival among patients with head and neck cancer in Japan. Int J Clin Oncol. 2016;21(3):517–22.PubMedCrossRef Takenaka Y, et al. Health insurance status and survival among patients with head and neck cancer in Japan. Int J Clin Oncol. 2016;21(3):517–22.PubMedCrossRef
7.
go back to reference Montoro JR, et al. Prognostic factors in squamous cell carcinoma of the oral cavity. Braz J Otorhinolaryngol. 2008;74(6):861–6.PubMedCrossRef Montoro JR, et al. Prognostic factors in squamous cell carcinoma of the oral cavity. Braz J Otorhinolaryngol. 2008;74(6):861–6.PubMedCrossRef
8.
go back to reference Massano J, et al. Oral squamous cell carcinoma: review of prognostic and predictive factors. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006;102(1):67–76.PubMedCrossRef Massano J, et al. Oral squamous cell carcinoma: review of prognostic and predictive factors. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006;102(1):67–76.PubMedCrossRef
9.
go back to reference Murphy CT, et al. Survival Impact of Increasing Time to Treatment Initiation for Patients With Head and Neck Cancer in the United States. J Clin Oncol. 2016;34(2):169–78.PubMedCrossRef Murphy CT, et al. Survival Impact of Increasing Time to Treatment Initiation for Patients With Head and Neck Cancer in the United States. J Clin Oncol. 2016;34(2):169–78.PubMedCrossRef
10.
go back to reference Brouha X, et al. Role of alcohol and smoking in diagnostic delay of head and neck cancer patients. Acta Otolaryngol. 2005;125(5):552–6.PubMedCrossRef Brouha X, et al. Role of alcohol and smoking in diagnostic delay of head and neck cancer patients. Acta Otolaryngol. 2005;125(5):552–6.PubMedCrossRef
11.
go back to reference Dekate KN. Why head and neck squamous cell carcinoma diagnosed so late? Influence of health care disparities and socio-economic factor. Oral Oncol. 2014;50(11):e63.PubMedCrossRef Dekate KN. Why head and neck squamous cell carcinoma diagnosed so late? Influence of health care disparities and socio-economic factor. Oral Oncol. 2014;50(11):e63.PubMedCrossRef
12.
go back to reference Noonan B. Understanding the reasons why patients delay seeking treatment for oral cancer symptoms from a primary health care professional: an integrative literature review. Eur J Oncol Nurs. 2014;18(1):118–24.PubMedCrossRef Noonan B. Understanding the reasons why patients delay seeking treatment for oral cancer symptoms from a primary health care professional: an integrative literature review. Eur J Oncol Nurs. 2014;18(1):118–24.PubMedCrossRef
13.
go back to reference Shafer WG. Initial mismanagement and delay in diagnosis of oral cancer. J Am Dent Assoc. 1975;90(6):1262–4.PubMedCrossRef Shafer WG. Initial mismanagement and delay in diagnosis of oral cancer. J Am Dent Assoc. 1975;90(6):1262–4.PubMedCrossRef
14.
go back to reference Gomez I, et al. Is early diagnosis of oral cancer a feasible objective? Who is to blame for diagnostic delay? Oral Dis. 2010;16(4):333–42.PubMedCrossRef Gomez I, et al. Is early diagnosis of oral cancer a feasible objective? Who is to blame for diagnostic delay? Oral Dis. 2010;16(4):333–42.PubMedCrossRef
15.
go back to reference Knopf A, Fritsche MK, Li Y, CXCR4. A New Player in an Old Scene? ORL J Otorhinolaryngol Relat Spec. 2017;79(1–2):34–42.PubMedCrossRef Knopf A, Fritsche MK, Li Y, CXCR4. A New Player in an Old Scene? ORL J Otorhinolaryngol Relat Spec. 2017;79(1–2):34–42.PubMedCrossRef
16.
go back to reference Hoffmann TK, et al. Response Evaluation in Head and Neck Oncology: Definition and Prediction. ORL J Otorhinolaryngol Relat Spec. 2017;79(1–2):14–23.PubMedCrossRef Hoffmann TK, et al. Response Evaluation in Head and Neck Oncology: Definition and Prediction. ORL J Otorhinolaryngol Relat Spec. 2017;79(1–2):14–23.PubMedCrossRef
17.
go back to reference Singer S, et al. Socio-economic disparities in long-term cancer survival-10 year follow-up with individual patient data. Support Care Cancer. 2017;25(5):1391–9.PubMedCrossRef Singer S, et al. Socio-economic disparities in long-term cancer survival-10 year follow-up with individual patient data. Support Care Cancer. 2017;25(5):1391–9.PubMedCrossRef
18.
go back to reference Welch HG, Fisher ES. Income and Cancer Overdiagnosis - When Too Much Care Is Harmful. N Engl J Med. 2017;376(23):2208–9.PubMedCrossRef Welch HG, Fisher ES. Income and Cancer Overdiagnosis - When Too Much Care Is Harmful. N Engl J Med. 2017;376(23):2208–9.PubMedCrossRef
19.
go back to reference Polesel J, et al. The impact of time to treatment initiation on survival from head and neck cancer in north-eastern Italy. Oral Oncol. 2017;67:175–82.PubMedCrossRef Polesel J, et al. The impact of time to treatment initiation on survival from head and neck cancer in north-eastern Italy. Oral Oncol. 2017;67:175–82.PubMedCrossRef
20.
21.
go back to reference Steenland K, Henley J, Thun M. All-cause and cause-specific death rates by educational status for two million people in two American Cancer Society cohorts, 1959–1996. Am J Epidemiol. 2002;156(1):11–21.PubMedCrossRef Steenland K, Henley J, Thun M. All-cause and cause-specific death rates by educational status for two million people in two American Cancer Society cohorts, 1959–1996. Am J Epidemiol. 2002;156(1):11–21.PubMedCrossRef
22.
go back to reference Choi SH, et al. Socioeconomic and Other Demographic Disparities Predicting Survival among Head and Neck Cancer Patients. PLoS One. 2016;11(3):e0149886.PubMedPubMedCentralCrossRef Choi SH, et al. Socioeconomic and Other Demographic Disparities Predicting Survival among Head and Neck Cancer Patients. PLoS One. 2016;11(3):e0149886.PubMedPubMedCentralCrossRef
23.
go back to reference Conway DI, et al. Estimating and explaining the effect of education and income on head and neck cancer risk: INHANCE consortium pooled analysis of 31 case-control studies from 27 countries. Int J Cancer. 2015;136(5):1125–39.PubMedCrossRef Conway DI, et al. Estimating and explaining the effect of education and income on head and neck cancer risk: INHANCE consortium pooled analysis of 31 case-control studies from 27 countries. Int J Cancer. 2015;136(5):1125–39.PubMedCrossRef
24.
go back to reference Rieke K, et al. Depression and survival in head and neck cancer patients. Oral Oncol. 2017;65:76–82.CrossRefPubMed Rieke K, et al. Depression and survival in head and neck cancer patients. Oral Oncol. 2017;65:76–82.CrossRefPubMed
25.
go back to reference Kim SA, et al. Pretreatment depression as a prognostic indicator of survival and nutritional status in patients with head and neck cancer. Cancer. 2016;122(1):131–40.PubMedCrossRef Kim SA, et al. Pretreatment depression as a prognostic indicator of survival and nutritional status in patients with head and neck cancer. Cancer. 2016;122(1):131–40.PubMedCrossRef
26.
go back to reference Barber B, et al. Depression as a predictor of postoperative functional performance status (PFPS) and treatment adherence in head and neck cancer patients: a prospective study. J Otolaryngol Head Neck Surg. 2015;44:38.PubMedPubMedCentralCrossRef Barber B, et al. Depression as a predictor of postoperative functional performance status (PFPS) and treatment adherence in head and neck cancer patients: a prospective study. J Otolaryngol Head Neck Surg. 2015;44:38.PubMedPubMedCentralCrossRef
Metadata
Title
Mono-institutional retrospective cohort analysis of the insurance status dependent access to ENT-professionals and survival in head and neck squamous cell carcinoma
Authors
Andreas Knopf
Simon Teutsch
Henning Bier
Publication date
01-12-2021
Publisher
BioMed Central
Published in
BMC Health Services Research / Issue 1/2021
Electronic ISSN: 1472-6963
DOI
https://doi.org/10.1186/s12913-020-06035-2

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