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Cancer Immunology, Immunotherapy

Issue 5/2016

Content (12 Articles)

Editorial

Anti-CD137 monoclonal antibodies and adoptive T cell therapy: a perfect marriage?

Bettina Weigelin, Elixabet Bolaños, Maria E. Rodriguez-Ruiz, Ivan Martinez-Forero, Peter Friedl, Ignacio Melero

Original Article

MHC class I chain-related molecule A and B expression is upregulated by cisplatin and associated with good prognosis in patients with non-small cell lung cancer

Riki Okita, Takuro Yukawa, Yuji Nojima, Ai Maeda, Shinsuke Saisho, Katsuhiko Shimizu, Masao Nakata

Original Article

Systemic delivery of chTNT-3/CpG immunoconjugates for immunotherapy in murine solid tumor models

Julie K. Jang, Leslie A. Khawli, David C. Canter, Peisheng Hu, Tian H. Zhu, Brian W. Wu, Trevor E. Angell, Zhongjun Li, Alan L. Epstein

Open Access Original Article

Poxvirus-based active immunotherapy synergizes with CTLA-4 blockade to increase survival in a murine tumor model by improving the magnitude and quality of cytotoxic T cells

Susan P. Foy, Stefanie J. Mandl, Tracy dela Cruz, Joseph J. Cote, Evan J. Gordon, Erica Trent, Alain Delcayre, James Breitmeyer, Alex Franzusoff, Ryan B. Rountree

Original Article

The tumor antigen N-glycolyl-GM3 is a human CD1d ligand capable of mediating B cell and natural killer T cell interaction

M. Virginia Gentilini, M. Eugenia Pérez, Pablo Mariano Fernández, Leonardo Fainboim, Eloísa Arana

Original Article

Human papillomavirus type 16 viral load is decreased following a therapeutic vaccination

Hannah N. Coleman, William W. Greenfield, Shawna L. Stratton, Rita Vaughn, Alexander Kieber, Andrea M. Moerman-Herzog, Horace J. Spencer, Wilbur. C. Hitt, Charles Matthew Quick, Laura F. Hutchins, Samuel G. Mackintosh, Ricky D. Edmondson, Stephen W. Erickson, Mayumi Nakagawa

Open Access Original Article

Oropharyngeal squamous cell carcinomas differentially express granzyme inhibitors

Pauline M. W. van Kempen, Rob Noorlag, Justin E. Swartz, Niels Bovenschen, Weibel W. Braunius, Jeroen F. Vermeulen, Ellen M. Van Cann, Wilko Grolman, Stefan M. Willems

Original Article

Non-small-cell lung cancer-induced immunosuppression by increased human regulatory T cells via Foxp3 promoter demethylation

Xing Ke, Shuping Zhang, Jian Xu, Genyan Liu, Lixia Zhang, Erfu Xie, Li Gao, Daqian Li, Ruihong Sun, Fang Wang, Shiyang Pan

Original Article

Enhanced local and systemic anti-melanoma CD8+ T cell responses after memory T cell-based adoptive immunotherapy in mice

Amanda Contreras, Siddhartha Sen, Andrew J. Tatar, David A. Mahvi, Justin V. Meyers, Prakrithi Srinand, Marulasiddappa Suresh, Clifford S. Cho

Original Article

Anti-tumor effects of DNA vaccine targeting human fibroblast activation protein α by producing specific immune responses and altering tumor microenvironment in the 4T1 murine breast cancer model

Qiu Xia, Fang-Fang Zhang, Fei Geng, Chen-Lu Liu, Ping Xu, Zhen-Zhen Lu, Bin Yu, Hui Wu, Jia-Xin Wu, Hai-Hong Zhang, Wei Kong, Xiang-Hui Yu

Webinar | 19-02-2024 | 17:30 (CET)

Keynote webinar | Spotlight on antibody–drug conjugates in cancer

Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.

Dr. Véronique Diéras
Prof. Fabrice Barlesi
Developed by: Springer Medicine