Issue 1/2017
Content (14 Articles)
Tumor-directed immunotherapy can generate tumor-specific T cell responses through localized co-stimulation
Peter Ellmark, Sara M. Mangsbo, Christina Furebring, Per Norlén, Thomas H. Tötterman
Low-dose interleukin-2 impairs host anti-tumor immunity and inhibits therapeutic responses in a mouse model of melanoma
Andrew Zloza, Neal D. Dharmadhikari, Erica J. Huelsmann, Joseph R. Broucek, Tasha Hughes, Frederick J. Kohlhapp, Howard L. Kaufman
Effective induction of cytotoxic T cells recognizing an epitope peptide derived from hypoxia-inducible protein 2 (HIG2) in patients with metastatic renal cell carcinoma
Wataru Obara, Takashi Karashima, Kazuyoshi Takeda, Renpei Kato, Yoichiro Kato, Mitsugu Kanehira, Ryo Takata, Keiji Inoue, Toyomasa Katagiri, Taro Shuin, Yusuke Nakamura, Tomoaki Fujioka
A case of pembrolizumab-induced type-1 diabetes mellitus and discussion of immune checkpoint inhibitor-induced type 1 diabetes
Young Kwang Chae, Lauren Chiec, Nisha Mohindra, Ryan Gentzler, Jyoti Patel, Francis Giles
Heterogeneity of CD8+ tumor-infiltrating lymphocytes in non-small-cell lung cancer: impact on patient prognostic assessments and comparison of quantification by different sampling strategies
Joseph M. Obeid, Nolan A. Wages, Yinin Hu, Donna H. Deacon, Craig L. Slingluff Jr.
Cardiac allograft rejection as a complication of PD-1 checkpoint blockade for cancer immunotherapy: a case report
Taofeek K. Owonikoko, Mukesh Kumar, Shu Yang, Alice O. Kamphorst, Rathi N. Pillai, Rama Akondy, Vivek Nautiyal, Monica S. Chatwal, Wendy M. Book, Anurag Sahu, Gabriel L. Sica, Rafi Ahmed, Suresh S. Ramalingam
High-efficiency lysis of cervical cancer by allogeneic NK cells derived from umbilical cord progenitors is independent of HLA status
John P. Veluchamy, A. Marijne Heeren, Jan Spanholtz, Jaap D. H. van Eendenburg, Daniëlle A. M. Heideman, Gemma G. Kenter, Henk M. Verheul, Hans J. van der Vliet, Ekaterina S. Jordanova, Tanja D. de Gruijl
Alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 can support immune responses toward tumors overexpressing ganglioside D3 in mice
Jonathan M. Eby, Levi Barse, Steven W. Henning, Martijn J. W. E. Rabelink, Jared Klarquist, Emily R. Gilbert, Adam M. Hammer, Manuel F. Fernandez, Nathan Yung, Safia Khan, Hannah G. Miller, Edward R. Kessler, Elizabeth Garrett-Mayer, Daniel F. Dilling, Rob C. Hoeben, I. Caroline Le Poole
Neutrophils from chronic lymphocytic leukemia patients exhibit an increased capacity to release extracellular traps (NETs)
Enrique Podaza, Florencia Sabbione, Denise Risnik, Mercedes Borge, María B. Almejún, Ana Colado, Horacio Fernández-Grecco, María Cabrejo, Raimundo F. Bezares, Analía Trevani, Romina Gamberale, Mirta Giordano
Phase I–II study of lenalidomide and alemtuzumab in refractory chronic lymphocytic leukemia (CLL): effects on T cells and immune checkpoints
Maria Winqvist, Fariba Mozaffari, Marzia Palma, Sandra Eketorp Sylvan, Lotta Hansson, Håkan Mellstedt, Anders Österborg, Jeanette Lundin
Immunological effects of a novel RNA-based adjuvant in liver cancer patients
Luisa Circelli, Annacarmen Petrizzo, Maria Tagliamonte, Regina Heidenreich, Maria Lina Tornesello, Franco M. Buonaguro, Luigi Buonaguro
Efficacy and toxicity of rechallenge with combination immune checkpoint blockade in metastatic melanoma: a case series
Lavinia Spain, Gerard Walls, Christina Messiou, Samra Turajlic, Martin Gore, James Larkin
Increased PD-L1 and T-cell infiltration in the presence of HLA class I expression in metastatic high-grade osteosarcoma: a rationale for T-cell-based immunotherapy
Yayan T. Sundara, Marie Kostine, Arjen H. G. Cleven, Judith V. M. G. Bovée, Marco W. Schilham, Anne-Marie Cleton-Jansen
A novel three-dimensional heterotypic spheroid model for the assessment of the activity of cancer immunotherapy agents
Sylvia Herter, Laura Morra, Ramona Schlenker, Jitka Sulcova, Linda Fahrni, Inja Waldhauer, Steffi Lehmann, Timo Reisländer, Irina Agarkova, Jens M. Kelm, Christian Klein, Pablo Umana, Marina Bacac