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Cancer Chemotherapy and Pharmacology

Issue 6/2001

Content (12 Articles)

Original Article

Phase I/II and pharmacologic study of irinotecan and carboplatin for patients with lung cancer

Mitsuo Sato, Masahiko Ando, Hironobu Minami, Yuichi Ando, Maki Ando, Masashi Yamamoto, Shuzo Sakai, Atsushi Watanabe, Takuya Ikeda, Yoshitaka Sekido, Hideo Saka, Kaoru Shimokata, Yoshinori Hasegawa

Original Article

Phase I clinical and pharmacokinetic trial of irofulven

James P. Thomas, Rhoda Arzoomanian, Dona Alberti, Chris Feierabend, Kimberly Binger, Kendra D. Tutsch, Thomas Steele, Rebecca Marnocha, Charlotte Smith, Sheri Smith, John MacDonald, George Wilding, Howard Bailey

Original Article

Phase I trial of capecitabine in combination with interferon alpha in patients with metastatic renal cancer: toxicity and pharmacokinetics

David Z. Chang, Thomas Olencki, Thomas G. Budd, David Peereboom, R. Ganapathi, Bruno Osterwalder, Ronald Bukowski

Original Article

A comparison of limited sampling strategies for prediction of Ecteinascidin 743 clearance when administered as a 24-h infusion

Charlotte van Kesteren, R. Mathôt, L. López-Lázaro, E. Cvitkovic, A. Taamma, J. Jimeno, C. Guzman, J. Schellens, J. Misset, E. Brain, M. Hillebrand, H. Rosing, J. Beijnen

Original Article

Phase I study of second-line chemotherapy with docetaxel and carboplatin in advanced non-small-cell lung cancer

Mikio Oka, Minoru Fukuda, Seiji Nagashima, Masaaki Fukuda, Akitoshi Kinoshita, Hiroshi Soda, Seiji Doi, Fumihiko Narasaki, Mitsuhiro Suenaga, Hiroshi Takatani, Yo-ichi Nakamura, Shigeru Kawabata, Junji Tsurutani, Tetsuro Kanda, Shigeru Kohno

Original Article

Gemcitabine activity in cervical cancer cell lines

Patricia Hernández, Primitivo Olivera, Alfonso Dueñas-Gonzalez, Miguel A. Pérez-Pastenes, Adolfo Zárate, Vilma Maldonado, Jorge Meléndez-Zajgla

Original Article

Antiangiogenic and antitumor effects of a protein kinase Cβ inhibitor in murine Lewis lung carcinoma and human Calu-6 non-small-cell lung carcinoma xenografts

Beverly A. Teicher, Krishna Menon, Enrique Alvarez, Elizabeth Galbreath, Chuan Shih, Margaret M. Faul

Clinical Trial Report

A phase II study of paclitaxel plus cisplatin for advanced non-small-cell lung cancer in Japanese patients

Hiroshi Sakai, Shuichi Yoneda, Tomohide Tamura, Yutaka Nishiwaki, Akira Yokoyama, Koshiro Watanabe, Nagahiro Saijo

Original Article

Stereospecific antitumor activity of radicicol oxime derivatives

Shiro Soga, Sreenath V. Sharma, Yukimasa Shiotsu, Makiko Shimizu, Harunobu Tahara, Kazuo Yamaguchi, Yoji Ikuina, Chikara Murakata, Tatsuya Tamaoki, Junichi Kurebayashi, Theodor W. Schulte, Leonard M. Neckers, Shiro Akinaga

Original Article

Doxorubicin-induced apoptosis in caspase-8-deficient neuroblastoma cells is mediated through direct action on mitochondria

Abdelhadi Rebbaa, Pauline M. Chou, Mohammad Emran, Bernard L. Mirkin

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Keynote webinar | Spotlight on antibody–drug conjugates in cancer

Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.

Dr. Véronique Diéras
Prof. Fabrice Barlesi
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